Results 111 to 120 of about 114,906 (281)

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

SEAFDEC/AQD highlights 2010 [PDF]

, 2011
The SEAFDEC Aquaculture Department is mandated to: 1) conduct scientific research to generate aquaculture technologies appropriate for Southeast Asia; 2) develop managerial, technical and skilled manpower for the aquaculture sector; and, 3) disseminate ...

core   +1 more source

HPV infection and immunochemical detection of cell-cycle markers in verrucous carcinoma of the penis [PDF]

, 2009
Penile verrucous carcinoma is a rare disease and little is known of its aetiology or pathogenesis. In this study we examined cell-cycle proteins expression and correlation with human papillomavirus infection in a series of 15 pure penile verrucous ...
A Ouban, AL Cubilla, AL Cubilla, AL Cubilla, AL Cubilla, AL Cubilla, AL Seixas, AS Masih, AS Narayana, B Kleter, C Dianzani, C Missero, Catherine Corbishley, CB Bunker, CL Haycox, Daniel M Berney, David M Prowse, DE Johnson, DM Prowse, E Ferreux, EF Velazquez, Elena Ktori, Elzbieta Stankiewicz, FT Kraus, GD Higgins, IB Roninson, Jack Cuzick, JC Noel, JR Nevins, KH Cuesta, KW Chan, KY Lam, KY Lam, L Gregoire, Laurence Ambroisine, LC Cubilla, LH Sobin, LL Villa, LV Ackerman, M Gualco, M Senba, M Serrano, M Wong, MA Rubin, MR Cupp, MT Kiyabu, Nicholas Watkin, PA Adegboyega, PA Hall, PH McKee, S Pilotti, Sakunthala C Kudahetti, SL Harris, T Sano, TH Cheung, VA Tron, VA Varma, Xiaoxi Zhang, Y Koyamatsu   +58 more
core   +1 more source

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

Epilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

Genome Characterization of the First Mimiviruses of Lineage C Isolated in Brazil

Frontiers in Microbiology, 2017
The family Mimiviridae, comprised by giant DNA viruses, has been increasingly studied since the isolation of the Acanthamoeba polyphaga mimivirus (APMV), in 2003.
Felipe L. Assis, Ana P. M. Franco-Luiz, Raíssa N. dos Santos, Fabrício S. Campos, Fábio P. Dornas, Paulo V. M. Borato, Ana C. Franco, Jônatas S. Abrahao, Philippe Colson, Bernard La Scola   +9 more
doaj   +1 more source

Influenza Virus A (H1N1) in Giant Anteaters (Myrmecophaga tridactyla)

Emerging Infectious Diseases, 2009
In February 2007, an outbreak of respiratory disease occurred in a group of giant anteaters (Myrmecophaga tridactyla) at the Nashville Zoo. Isolates from 2 affected animals were identified in March 2007 as a type A influenza virus related to human influenza subtype H1N1.
Sally Nofs, Mohamed Abd-Eldaim, Kathy V. Thomas, David Toplon, Dawn Rouse, Melissa Kennedy   +5 more
openaire   +3 more sources

Boiling Acid Mimics Intracellular Giant Virus Genome Release [PDF]

, 2019
SummarySince their discovery, giant viruses have expanded our understanding of the principles of virology. Due to their gargantuan size and complexity, little is known about the life cycles of these viruses. To answer outstanding questions regarding giant virus infection mechanisms, we set out to determine biomolecular conditions that promote giant ...
Schrad, Jason R., Abrahão, Jônatas S., Cortines, Juliana R., Parent, Kristin N.   +3 more
openaire   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Pithovirus sibericum, a new bona fide member of the Fourth TRUC club

Frontiers in Microbiology, 2015
Nucleocytoplasmic large DNA viruses, or representatives of the proposed order Megavirales, include giant viruses of Acanthamoeba that were discovered over the last 12 years and are bona fide microbes.
Vikas eSharma, Vikas eSharma, Philippe eColson, Philippe eColson, Olivier eChabrol, Pierre ePontarotti, Didier eRaoult, Didier eRaoult   +7 more
doaj   +1 more source

Continuous year-round isolation of giant viruses from brackish shoreline soils

Frontiers in Microbiology
Giant viruses, categorized under Nucleocytoviricota, are believed to exist ubiquitously in natural environments. However, comprehensive reports on isolated giant viruses remain scarce, with limited information available on unrecoverable strains, viral ...
Motohiro Akashi, Masaharu Takemura, Seiichi Suzuki   +2 more
doaj   +1 more source