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Giants among larges: how gigantism impacts giant virus entry into amoebae
Current Opinion in Microbiology, 2016The proposed order Megavirales comprises the nucleocytoplasmic large DNA viruses (NCLDV), infecting a wide range of hosts. Over time, they co-evolved with different host cells, developing various strategies to penetrate them. Mimiviruses and other giant viruses enter cells through phagocytosis, while Marseillevirus and other large viruses explore ...
Rodrigo Araújo Lima, Rodrigues +3 more
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Giant-cell pneumonia caused by parainfluenza virus
The Journal of Pediatrics, 1979IN 1959, Enders and collaborators I isolated measles virus from the lungs of patients dying of giant cell pneumonia. Since then, this virus has been firmly established as a causative agent of this disease in patients with leukemia ~ or immunodeficiency diseases? A recent pathology textbook describes measles virus as the sole agent responsible for giant
G, Delage +4 more
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Chemical & Engineering News Archive, 2014
Thirty thousand years ago mammoths and other giant fauna roamed Earth. So, too, did a kind of giant virus that is so large it can be seen under a light microscope. Yet unlike many giant land animals this megavirus, Pithovirus sibericum, is still around. It is not the first megavirus discovered, but at 1.5 µm in length, it is the largest.
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Thirty thousand years ago mammoths and other giant fauna roamed Earth. So, too, did a kind of giant virus that is so large it can be seen under a light microscope. Yet unlike many giant land animals this megavirus, Pithovirus sibericum, is still around. It is not the first megavirus discovered, but at 1.5 µm in length, it is the largest.
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The evolution of giant virus genomes
Science, 2017Viral Genomics Some giant viruses encode a genome larger than that of some bacteria, but their evolutionary history is a mystery. Examining the genomes within a sample from a wastewater treatment plant in Austria, Schulz et al. assembled a previously undiscovered giant virus genome, which they used to mine genetic databases for related viruses.
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Hepatis C Virus: A Giant Leap Forward
Hepatology, 1990A random–primed complementary DNA library was constructed from plasma containing the uncharacterized non–A, non–B hepatitis (NANBH) agent and screened with serum from a patient diagnosed with NANBH. A complementary DNA clone was isolated that was shown to encode an antigen associated specifically with NANBH infections.
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Measles virus giant cell inducing factor (fusion factor)
Virology, 1965Abstract Treatment of a line of human amnion cells (AV3) with high titers of measles virus resulted in a rapid sequence of morphological alterations. Cell limits became less distinct within 30 minutes, and cytoplasmic fusion was complete within 5 hours. Measles virus rendered incapable of replication by irradiation with ultraviolet light retained the
M R, CASCARDO, D T, KARZON
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Host–virus interactions and defense mechanisms for giant viruses
Annals of the New York Academy of Sciences, 2020AbstractGiant viruses, with virions larger than 200 nm and genomes larger than 340 kilobase pairs, modified the now outdated perception of the virosphere. With virions now reported reaching up to 1.5 μm in size and genomes of up to 2.5 Mb encoding components shared with cellular life forms, giant viruses exhibit a complexity similar to microbes, such ...
Chelkha, Nisrine +3 more
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Microbe makes a virus to fight a giant virus
New Scientist, 2016A voracious marine predator plagued by a giant virus has a defense system people have never seen before--it fights back by making its very own virus. The individuals that make these bioweapons sacrifice themselves to save their fellow predators. The single-celled predator, Cafeteria roenbergensis, swims in coastal waters catching bacteria.
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Search for varicella zoster virus in giant cell arteritis
Annals of Neurology, 1998AbstractPolymerase chain reaction and immunohistochemical analyses of formalin‐fixed temporal arteries from 10 pathologically verified cases of giant cell arteritis did not reveal varicella zoster virus antigen or DNA.
C, Nordborg +6 more
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Giant Cell Myocarditis due to Coxsackie B2 Virus Infection
Cardiology, 1997Giant cell myocarditis is a rare disorder characterized by the histologic hallmark of diffuse inflammatory infiltrates with the appearance of multinucleated giant cells. We report on a 52-year-old man who died of rapidly progressive cardiogenic shock due to giant cell myocarditis.
T, Meyer +3 more
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