Results 221 to 230 of about 2,070,727 (280)
Abstract Objective We have established a comprehensive sample handling protocol designed for the multiscale assessment of epileptogenic tissue. This protocol aims to identify novel therapeutic targets and enhance the diagnosis and stratification of patients with drug‐resistant epilepsy, thereby optimizing their treatment with anti‐seizure medications ...
Jenni Kyyriäinen +24 more
wiley +1 more source
We outline the diversity of pests, weeds and plant pathogens absent from New Zealand that threaten forage production, examine their potential import pathways, and outline the challenges of managing them should they arrive. The number and diversity of threats and pathways indicates ongoing incursions are inevitable.
Craig B. Phillips +9 more
wiley +1 more source
Novel Z-DNA binding domains in giant viruses. [PDF]
Romero MF +9 more
europepmc +1 more source
Applications of Multifunctional Hydrogel in Tissue Engineering and Regenerative Medicine
Schematic illustration showing multifunctional hydrogels in the application of tissue engineering and regenerative medicine. ABSTRACT Hydrogels, with excellent hydrophilicity and high‐water content, have emerged as highly versatile biomaterials for tissue engineering and regenerative medicine.
Jieran Lyu +4 more
wiley +1 more source
Complex transcriptional regulations of a hyperparasitic quadripartite system in giant viruses infecting protists. [PDF]
Bessenay A +8 more
europepmc +1 more source
Inflammation and Cancer: Molecular Mechanisms and Therapeutic Targets
Chronic inflammation fuels tumorigenesis via “internal drivers” and “external attractions.” Targeting these core mechanisms with combined therapies/novel deliveries enables precise, potent anti‐inflammatory–antitumor treatment. ABSTRACT Inflammation is a core pathological factor regulating tumor initiation, progression, and therapeutic resistance, and ...
Xiaodie Liu +4 more
wiley +1 more source
Progress in RNA‐Targeted Therapeutics for Human Diseases
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang +10 more
wiley +1 more source
Age of innovation: Progress in systematic botany in the 20th century
Abstract Systematic botany can be regarded as the oldest of the botanical sciences, having originated with the ancient Greeks. Although much progress has been achieved in systematic botany over nearly two millennia, in the 20th century, many significant innovations took place in revealing processes of evolution, principles and methods of classification,
Tod F. Stuessy
wiley +1 more source
Genetic Pigmentary Disorders: From Molecular Mechanisms to Clinical Manifestations
ABSTRACT Genetic pigmentary disorders represent a diverse group of genetic conditions characterized by alterations in melanin production and transport and melanocyte development, resulting from single‐gene pathological variants. These disorders encompass both hypopigmentary and hyperpigmentary phenotypes, affecting not only skin pigmentation but also ...
Ken Okamura, Tamio Suzuki
wiley +1 more source

