Results 221 to 230 of about 2,070,727 (280)

Multimodal approach to characterize surgically removed epileptogenic zone from patients with focal drug‐resistant epilepsy: From operating room to wet lab

open access: yesEpilepsia Open, Volume 11, Issue 1, Page 347-362, February 2026.
Abstract Objective We have established a comprehensive sample handling protocol designed for the multiscale assessment of epileptogenic tissue. This protocol aims to identify novel therapeutic targets and enhance the diagnosis and stratification of patients with drug‐resistant epilepsy, thereby optimizing their treatment with anti‐seizure medications ...
Jenni Kyyriäinen   +24 more
wiley   +1 more source

The Vulnerability of New Zealand Forage Plants to Incursions by New Pests, Pathogens and Weeds, and the Case for Greater Protection

open access: yesNew Zealand Journal of Agricultural Research, Volume 69, Issue 1, February 2026.
We outline the diversity of pests, weeds and plant pathogens absent from New Zealand that threaten forage production, examine their potential import pathways, and outline the challenges of managing them should they arrive. The number and diversity of threats and pathways indicates ongoing incursions are inevitable.
Craig B. Phillips   +9 more
wiley   +1 more source

Novel Z-DNA binding domains in giant viruses. [PDF]

open access: yesJ Biol Chem
Romero MF   +9 more
europepmc   +1 more source

Applications of Multifunctional Hydrogel in Tissue Engineering and Regenerative Medicine

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Schematic illustration showing multifunctional hydrogels in the application of tissue engineering and regenerative medicine. ABSTRACT Hydrogels, with excellent hydrophilicity and high‐water content, have emerged as highly versatile biomaterials for tissue engineering and regenerative medicine.
Jieran Lyu   +4 more
wiley   +1 more source

Complex transcriptional regulations of a hyperparasitic quadripartite system in giant viruses infecting protists. [PDF]

open access: yesNat Commun
Bessenay A   +8 more
europepmc   +1 more source

Inflammation and Cancer: Molecular Mechanisms and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Chronic inflammation fuels tumorigenesis via “internal drivers” and “external attractions.” Targeting these core mechanisms with combined therapies/novel deliveries enables precise, potent anti‐inflammatory–antitumor treatment. ABSTRACT Inflammation is a core pathological factor regulating tumor initiation, progression, and therapeutic resistance, and ...
Xiaodie Liu   +4 more
wiley   +1 more source

Progress in RNA‐Targeted Therapeutics for Human Diseases

open access: yesMedComm, Volume 7, Issue 2, February 2026.
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang   +10 more
wiley   +1 more source

Age of innovation: Progress in systematic botany in the 20th century

open access: yesTAXON, Volume 75, Issue 1, Febuary 2026.
Abstract Systematic botany can be regarded as the oldest of the botanical sciences, having originated with the ancient Greeks. Although much progress has been achieved in systematic botany over nearly two millennia, in the 20th century, many significant innovations took place in revealing processes of evolution, principles and methods of classification,
Tod F. Stuessy
wiley   +1 more source

Genetic Pigmentary Disorders: From Molecular Mechanisms to Clinical Manifestations

open access: yesThe Journal of Dermatology, Volume 53, Issue 2, Page 169-179, February 2026.
ABSTRACT Genetic pigmentary disorders represent a diverse group of genetic conditions characterized by alterations in melanin production and transport and melanocyte development, resulting from single‐gene pathological variants. These disorders encompass both hypopigmentary and hyperpigmentary phenotypes, affecting not only skin pigmentation but also ...
Ken Okamura, Tamio Suzuki
wiley   +1 more source

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