Results 81 to 90 of about 2,070,727 (280)

Endogenous giant viruses contribute to intraspecies genomic variability in the model green alga Chlamydomonas reinhardtii

bioRxiv, 2021
Chlamydomonas reinhardtii is an important eukaryotic alga that has been studied as a model organism for decades. Despite extensive history as a model system, phylogenetic and genetic characteristics of viruses infecting this alga have remained elusive ...
M. Moniruzzaman, F. Aylward
semanticscholar   +1 more source

Discovery and Further Studies on Giant Viruses at the IHU Mediterranee Infection That Modified the Perception of the Virosphere

Viruses, 2019
The history of giant viruses began in 2003 with the identification of Acanthamoeba polyphaga mimivirus. Since then, giant viruses of amoeba enlightened an unknown part of the viral world, and every discovery and characterization of a new giant virus ...
Clara Rolland, Julien Andreani, Amina Cherif Louazani, Sarah Aherfi, Rania Francis, Rodrigo Rodrigues, Ludmila Santos Silva, Dehia Sahmi, Said Mougari, Nisrine Chelkha, Meriem Bekliz, Lorena Silva, Felipe Assis, Fábio Dornas, Jacques Yaacoub Bou Khalil, Isabelle Pagnier, Christelle Desnues, Anthony Levasseur, Philippe Colson, Jônatas Abrahão, Bernard La Scola   +20 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

A Phylogenomic Study of Acanthamoeba polyphaga Draft Genome Sequences Suggests Genetic Exchanges With Giant Viruses

Frontiers in Microbiology, 2018
Acanthamoeba are ubiquitous phagocytes predominant in soil and water which can ingest many microbes. Giant viruses of amoebae are listed among the Acanthamoeba-resisting microorganisms.
Nisrine Chelkha, Anthony Levasseur, Pierre Pontarotti, Didier Raoult, Bernard La Scola, Philippe Colson   +5 more
doaj   +1 more source

Characteristics of Wetting-Induced Bacteriophage Blooms in Biological Soil Crust. [PDF]

, 2019
Biological soil crusts (biocrusts) are photosynthetic "hot spots" in deserts and cover ∼12% of the Earth's terrestrial surface, and yet they face an uncertain future given expected shifts in rainfall events.
Northen, Trent R, Roux, Simon, Swenson, Tami L, Trubl, Gareth, Van Goethem, Marc W   +4 more
core   +2 more sources

A novel capsid protein network allows the characteristic internal membrane structure of Marseilleviridae giant viruses

bioRxiv, 2021
Marseilleviridae is a family of the new order of giant viruses, which exhibit a characteristic inner membrane. Here, we investigated the entire structure of tokyovirus, a species of Marseillevirus at 7.7 Å resolution using 1 MV high-voltage cryo-EM and ...
Akane Chihara, Raymond N. Burton-Smith, N. Kajimura, K. Mitsuoka, Kenta Okamoto, Chihong Song, K. Murata   +6 more
semanticscholar   +1 more source

Structures of giant icosahedral eukaryotic dsDNA viruses [PDF]

Current Opinion in Virology, 2011
In the last twenty years, numerous giant, dsDNA, icosahedral viruses have been discovered and assigned to the nucleocytoplasmic large dsDNA virus (NCLDV) clade. The major capsid proteins of these viruses consist of two consecutive jelly-roll domains, assembled into trimers, with pseudo 6-fold symmetry.
Chuan, Xiao, Michael G, Rossmann
openaire   +2 more sources

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Distinguishing Infections on Different Graph Topologies [PDF]

, 2013
The history of infections and epidemics holds famous examples where understanding, containing and ultimately treating an outbreak began with understanding its mode of spread.
Caramanis, Constantine, Mannor, Shie, Milling, Chris, Shakkottai, Sanjay   +3 more
core  

Recoverable prevalence in growing scale-free networks and the effective immunization [PDF]

, 2003
We study the persistent recoverable prevalence and the extinction of computer viruses via e-mails on a growing scale-free network with new users, which structure is estimated form real data.
Hayashi, Yukio, Matsukubo, Jun, Minoura, Masato   +2 more
core   +2 more sources