Results 51 to 60 of about 1,628,791 (312)
Philanthropy: A Gift or Investment? [PDF]
CAF latest report on philanthropic habits, "Philanthropy A gift or investment?", reveals striking differences in approaches to giving between generations.
David Stead
core
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Trust and ethics: ambivalent foundations of relationship and sui generis forms of gift
Is there a circular relationship between trust and ethics? Is it possible to alter their relationship, changing the perception that social actors have of them?
Simone D'Alessandro
doaj +1 more source
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
“Here’s a Little Something for You”: How Therapists Respond to Client Gifts [PDF]
Descriptions by 12 therapists of their experiences receiving tangible gifts from clients are examined. Using consensual qualitative research (C. E. Hill, B. J. Thompson, & E. N.
Hess, Shirley A +3 more
core +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
A Corpus Analysis of Metaphorical Expressions in Covid-19 Open Research Dataset(CORD19)
Metaphors play a significant role in shaping our thoughts and processes of communication. They are extensively used in everyday language and hence are an indispensable part of shaping human thought and language structures.
Shazia Riaz Dar
doaj
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Menorah Review (No. 6, Winter, 1986) [PDF]
On How Being Jewish Is Different -- Is Good Business Good?
core +1 more source

