Results 161 to 170 of about 60,062 (314)

The Host Cell Factor Phosphatase‐2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type‐1

Advanced Science, EarlyView.
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth, Christoph F. Jacob, Alexandra Nguyen, Mandy Beyer, Andreas O. Mieland, Mario Dejung, Jia‐Xuan Chen, Walburgis Brenner, Christina Ehrhardt, Andreas Henke, Oliver H. Krämer   +10 more
wiley   +1 more source

Cognitive and Reading Profiles of Gifted Students with Learning Disabilities: Implications for Assessment and Identification. [PDF]

Behav Sci (Basel)
Padeliadu S, Voulgari A.
europepmc   +1 more source

DTX3L Inhibits the EMT, Metastasis, and Stem‐Like Features of Gastric Cancer Through Promoting GSK‐3β Dependent SNAI1 Decay

Advanced Science, EarlyView.
This research identifies DTX3L as a critical tumor suppressor that inhibits epithelial‐mesenchymal transition (EMT), invasion and metastasis in gastric cancer. By functioning as an E3 ubiquitin ligase, DTX3L targets the master EMT regulator SNAI1 for GSK‐3β‐dependent proteasomal degradation.
Yang Chen, Zhen Li, Jiajia Shen, Jingyu Lin, Xiaoli Zhao, Rui Zhang, Ying Han, Zhen Wang   +7 more
wiley   +1 more source

The importance of challenging tasks for mathematically gifted students

, 2002
This study explored how the challenge of mathematical problem solving could be increased to provide greater value and interest to gifted students. Ten pairs of gifted 11-and 12-year old students were first studied as they engaged in problem solving ...
Diezmann, Carmel M., Watters, James J.
core  

Intellectual foundations of exceptionality: An integration scheme

Revista Española de Pedagogía
Antoni Castelló Tarrida
doaj   +1 more source

Supports and Barriers in the Talent Development of Socio-Economically Disadvantaged Gifted Students: A Retrospective Narrative Inquiry. [PDF]

J Intell
Li CC.
europepmc   +1 more source

tBid‐Mediated Genetic Ablation of Connective Tissue Cells Reveals Their Key Regulatory Function During Limb Regeneration in Axolotls

Advanced Science, EarlyView.
We establish a tBid‐mediated cell ablation system in axolotls, achieve rapid and efficient ablation of multiple cell types, including muscle stem cell, spinal cord cell, and connective tissue (CT) cells. We investigate the role of CT using tBid‐mediated CT ablation and identify its essential role for limb development and regeneration.
Yan Hu, Weimin Feng, Zitian He, Jiayi Zeng, Jingyi Tang, Shulin Li, Tongbo Yu, Sulei Fu, Hui Ma, Binbin Lu, Yanmei Liu, Ji‐Feng Fei   +11 more
wiley   +1 more source

Academic self-concept of gifted students : when the big fish becomes small

, 2004
Students' self-concept is developed primarily on the basis of a sense of belonging to the group (an assimilation effect) and a 'comparison of competency with other students (a big-fish-little-pond effect).
Yeung, Alexander Seeshing, Wong, Edwin King Por, Chow, Phoebe Ching-Wa, Fai, Luk, Chow, Alan Ping-Yan   +4 more
core  

The gift [PDF]

The Lancet, 2019
openaire   +2 more sources

Kinsenoside Targets IDH1 to Restore Microglial Immune‐Metabolic Homeostasis for Alzheimer's Disease Therapy

Advanced Science, Volume 13, Issue 36, 29 June 2026.
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li, Yajin Liao, Yan‐bo Zhao, Hongxing Wu, Tong Jin, Shuoshuo Li, Yuhan Liu, Peng Li, Songying Ouyang, Zekai Li, YuTing Xia, Qian Hua, Rui‐Yuan Pan, Zengqiang Yuan   +13 more
wiley   +1 more source