Results 31 to 40 of about 13,120 (243)

Effect of [10]-Gingerol on [Ca2+]i and Cell Death in Human Colorectal Cancer Cells

Molecules, 2009
The effect of [10]-gingerol on cytosol free Ca2+ concentration ([Ca2+]i) and viability is large unknown. This study examines the early signaling effects of [10]-gingerol on human colorectal cancer cells.
Chung-Yi Chen, Yi-Wen Li, Soong-Yu Kuo
doaj   +1 more source

The inhibitory effect of 6-gingerol and cisplatin on ovarian cancer and antitumor activity: In silico, in vitro, and in vivo

Frontiers in Oncology, 2023
Background Epithelial ovarian cancer is very common in women and causes hundreds of deaths per year worldwide. Chemotherapy drugs including cisplatin have adverse effects on patients’ health.
Z. Salari, A. Khosravi, E. Pourkhandani, Elaheh Molaakbari, Ehsan Salarkia, A. Keyhani, I. Sharifi, H. Tavakkoli, Samira Sohbati, S. Dabiri, Guo-Gang Ren, Mohammad Shafie’ei   +11 more
semanticscholar   +1 more source

QbD-Optimized, Phospholipid-Based Elastic Nanovesicles for the Effective Delivery of 6-Gingerol: A Promising Topical Option for Pain-Related Disorders

International Journal of Molecular Sciences, 2023
In this study, elastic nanovesicles, constructed of phospholipids optimized by Quality by Design (QbD), release 6-gingerol (6-G), a natural chemical that may alleviate osteoporosis and musculoskeletal-related pain. A 6-gingerol-loaded transfersome (6-GTF)
Mohammed Y. Ghazwani, M. H. Alqarni, Umme Hani, Aftab Alam   +3 more
semanticscholar   +1 more source

Pivotal Role of Iron Homeostasis in the Induction of Mitochondrial Apoptosis by 6-Gingerol Through PTEN Regulated PD-L1 Expression in Embryonic Cancer Cells

Frontiers in Oncology, 2021
Embryonic cancer stem cells (CSCs) can differentiate into any cancer type. Targeting CSCs with natural compounds is a promising approach as it suppresses cancer recurrence with fewer adverse effects.
Nipin Sp, Dong Young Kang, Eun Seong Jo, Jin-Moo Lee, Jin-Moo Lee, Se Won Bae, Kyoung-Jin Jang   +6 more
doaj   +1 more source

6-Gingerol regulates triglyceride and cholesterol biosynthesis to improve hepatic steatosis in MAFLD by activating the AMPK-SREBPs signaling pathway.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023
Excessive synthesis of triglycerides and cholesterol accelerates the progression of hepatic steatosis in metabolic-associated fatty liver disease (MAFLD).
Qing-Song Xia, Fu-Er Lu, Yu Chen, Jing-Bin Li, Zhao-Yi Huang, Ke Fang, Meilin Hu, Yujin Guo, Hui Dong, Li-Jun Xu, Jing Gong   +10 more
semanticscholar   +1 more source

6-Gingerol Alleviates Neonatal Hypoxic-Ischemic Cerebral and White Matter Injury and Contributes to Functional Recovery

Frontiers in Pharmacology, 2021
Hypoxic-ischemic encephalopathy (HIE) is one main cause of neonatal death and disability, causing substantial injury to white and gray matter, which can lead to severe neurobehavioral dysfunction, including intellectual disability and dyskinesia ...
Man Zhao, Yuan Yao, Jingyi Du, Liang Kong, Tiantian Zhao, Dong Wu, Lajie Man, Wenjuan Zhou   +7 more
doaj   +1 more source

6-gingerol ameliorates weight gain and insulin resistance in metabolic syndrome rats by regulating adipocytokines

Saudi Pharmaceutical Journal, 2023
Metabolic syndrome (MetS) can lead to increase of insulin resistance (IR) and visceral adipose tissue production of adipocytokines. 6-gingerol is known to have antioxidant and anti-inflammatory activities.
Shirly Gunawan, Eka Munika, E. Wulandari, Frans Ferdinal, E. Purwaningsih, P. Wuyung, M. Louisa, V. Soetikno   +7 more
semanticscholar   +1 more source

PENERAPAN PARTIAL LEAST SQUARES PADA DATA GINGEROL [PDF]

, 2010
Model multivariate calibration bertujuan untuk menduga ukuran-ukuran yang mahal diperoleh dengan menggunakan ukuran-ukuran yang murah dan mudah. Ada beberapa masalah yang sering terjadi pada pemodelan kalibrasi, diantaranya dan multikolinear.
Margaretha Ohyver, Margaretha, Ohyver
core   +1 more source

Quantitative profiling of gingerol and its derivatives in Australian ginger

, 2021
Gingerols and their shogaol derivatives play an important role in determining the sensory and organoleptic properties of ginger. In this study, 6-gingerol, 8-gingerol, 10-gingerol and 6-shogaol were quantified in 98 samples of dried Australian processing-
Mani Naiker (9822011), Philip Brown (9783572), Simon White (9844901), Janice Mani (9815900), Joel Johnson (9808013)   +4 more
core   +1 more source

Gingerol ameliorates neuronal damage induced by hypoxia‐reoxygenation via the miR‐210/brain‐derived neurotrophic factor axis

Kaohsiung Journal of Medical Sciences, 2022
The specific mechanism of gingerol in cerebral ischemia remains unknown. A neuroprotective function for miR‐210 in cerebral ischemia has been identified.
Yang Zhai, Bu‐Gu Liu, Xue‐Ni Mo, Min Zou, Xiao‐Ping Mei, Wei Chen, Guo‐Dong Huang, Lin Wu   +7 more
doaj   +1 more source