Results 21 to 30 of about 13,120 (243)

Evaluation of the inhibitory effect of Gingerol on bacteria and fungi isolated from the vagina

open access: yesMedical Journal of Babylon
Background: Gingerol is extracted from the rhizomes of ginger. It showed a clear effect on the bacteria and the Candida isolation from the vagina, and the highest effect was at a concentration of 30 mg/mL.
Heba Hadid Rashed   +2 more
doaj   +2 more sources

Progress in Research on the Health Effects and Mechanisms of 6-Gingerol and in Development of Oral Delivery Systems for It [PDF]

open access: yesShipin Kexue, 2023
6-Gingerol is the major pungent component in ginger. It possesses a variety of health benefits including antitumor, anti-inflammatory and antioxidant, hypoglycemic, hypolipidemic and hypotensive activities as well as colitis prevention and treatment ...
TIAN Wenni, SONG Mingyue, LÜ Muwen, WANG Qun, CAO Yong, XIAO Jie
doaj   +1 more source

6-Gingerol attenuates subarachnoid hemorrhage-induced early brain injury via GBP2/PI3K/AKT pathway in the rat model

open access: yesFrontiers in Pharmacology, 2022
Numerous studies have elucidated the neuroprotective effect of 6-gingerol in central nervous system diseases. However, the potential role and mechanism of 6-gingerol on early brain injury (EBI) after subarachnoid hemorrhage (SAH) remains poorly ...
Hui Tang   +11 more
doaj   +1 more source

The effects of 6-gingerol on proliferation, differentiation, and maturation of osteoblast-like MG-63 cells [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 2015
We investigated whether 6-gingerol affects the maturation and proliferation of osteoblast-like MG63 cells in vitro. Osteoblast-like MG63 cells were treated with 6-gingerol under control conditions, and experimental inflammation was induced by tumor ...
J.Z. Fan, X. Yang, Z.G. Bi
doaj   +3 more sources

Pharmacokinetics of 6-Gingerol, 8-Gingerol, 10-Gingerol, and 6-Shogaol and Conjugate Metabolites in Healthy Human Subjects [PDF]

open access: yesCancer Epidemiology, Biomarkers & Prevention, 2008
Abstract Background: Ginger shows promising anticancer properties. No research has examined the pharmacokinetics of the ginger constituents 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol in humans. We conducted a clinical trial with 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol, examining the pharmacokinetics and tolerability of
Suzanna M, Zick   +7 more
openaire   +2 more sources

Antineutrophil properties of natural gingerols in models of lupus [PDF]

open access: yesJCI Insight, 2021
Ginger is known to have antiinflammatory and antioxidative effects and has traditionally been used as an herbal supplement in the treatment of various chronic diseases. Here, we report antineutrophil properties of 6-gingerol, the most abundant bioactive compound of ginger root, in models of lupus and antiphospholipid syndrome (APS).
Ramadan A. Ali   +8 more
openaire   +3 more sources

6-Gingerol Alleviates Ferroptosis and Inflammation of Diabetic Cardiomyopathy via the Nrf2/HO-1 Pathway

open access: yesOxidative Medicine and Cellular Longevity, 2022
Background. Diabetes mellitus (DM) can induce cardiomyocyte injury and lead to diabetic cardiomyopathy (DCM) which presently has no specific treatments and consequently increase risk of mortality. Objective.
Sheng-fa Wu   +7 more
semanticscholar   +1 more source

Cardioprotection by 6-gingerol in diabetic rats [PDF]

open access: yesBiochemical and Biophysical Research Communications, 2016
The current study was conducted to evaluate the effect of 6-gingerol (6G) on cardiac complications in streptozotocin (STZ)-induced diabetic (DM) rats. STZ-induced DM rats (single 50 mg/kg i.p. injection, 15 days prior to drug treatment) or time-matched controls were treated with 6G (75 mg/day route orally).
El-Bassossy, Hany M.   +5 more
openaire   +3 more sources

Molecular mechanism of inhibition of 8-gingerol on proliferation of breast cancer cells

open access: yesDi-san junyi daxue xuebao, 2019
Objective To investigate the effect of cell cycle on breast cancer cells by 8-gingerol. Methods The cell viability of breast cancer cells MDA-MB-231 and MCF-7 after treated by 8-gingerol at the doses of 0, 10, 20, 30 or 40 μmol/L for 24, 48 or 72 h was ...
YANG Chong, FU Ruoqiu, GAO Ning
doaj   +1 more source

Drying ginger and preserving 6-gingerol content [PDF]

open access: yes, 2017
Ginger rhizome (Zingiber officinale Roscoe) is widely used as a spice or a folk medicine. 6-gingerol is the major bioactive component in fresh ginger and has numerous physiological effects.
Li, Lizhuo
core   +1 more source

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