Upregulation of lysyl oxidase expression in cyclosporin A-induced gingival overgrowth
Lysyl oxidase (LOX) is involved in the initial steps of converting soluble monomers of collagen and elastin into insoluble fibers in the extracellular matrix. LOX was found to be upregulated in some fibrotic diseases.
Chung-Hung Tsai +2 more
doaj +1 more source
Supra and subgingival application of antiseptics or antibiotics during periodontal therapy
Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero +5 more
wiley +1 more source
Nifedipine-Induced gingival overgrowth
Objective: The objective of the present study was to evaluate gingival overgrowth induced by nifedipine and to correlate it with plaque accumulation.
Ornella Florio +5 more
doaj +1 more source
Hereditary gingival fibromatosis: clinical and ultrastructural features of a new family [PDF]
Objective: This article describes the diagnosis, clinical and microscopic (histopathology and ultrastructural) features and treatment of a new family with hereditary gingival fibromatosis (HGF) and highlights the importance of this genetic condition ...
Alves, Lucas Rodrigues +6 more
core +1 more source
Periodontitis and metabolic diseases (diabetes and obesity): Tackling multimorbidity
Abstract Noncommunicable diseases (NCDs) are multifactorial, long‐term, chronic conditions that represent a burden to health‐care systems worldwide as they can only be controlled rather than cured; hence, they require long‐term care. With the exponential increase in NCDs, the occurrence of individuals presenting with more than one chronic disease is ...
Crystal Marruganti +2 more
wiley +1 more source
Incidence of amlodipine-induced gingival overgrowth in the rural population of Loni
Aims: Since the incidence of gingival overgrowth induced by amlodipine remains poorly defined, this study was carried out with an aim to determine the incidence.
Avneesh Tejnani +6 more
doaj +1 more source
Epithelial to Mesenchymal Transition in Gingival Overgrowth [PDF]
Epithelial to mesenchymal transition (EMT) occurs normally in development. In pathology, EMT drives cancer and fibrosis. Medication with phenytoin, nifedipine, and cyclosporine-A often causes gingival overgrowth. Based partly on the histopathology of gingival overgrowth, the present study investigates the hypothesis that EMT could contribute to its ...
Siddika Selva, Sume +4 more
openaire +2 more sources
The prominent side effect of the immunosuppressive drug cyclosporine A (CsA) is gingival overgrowth. Hypoxia-inducible factor (HIF)-1α regulates a wide variety of profibrogenic genes, which are closely associated with tissue fibrosis.
Chung-Hung Tsai +5 more
doaj +1 more source
Retrospective analysis of the correlation between the facial biotype and the inclination of the upper canine cusp axis to the occlusal plane [PDF]
Permanent maxillary canines are the second most frequently impacted teeth and the prevalence of this clinical condition is estimated to be 1-2% in the general population.
Cielo, A. +4 more
core +1 more source
Fibroblasts Collagen Production and Histological Alterations in Hereditary Gingival Fibromatosis [PDF]
Hereditary gingival fibromatosis is a disorder for which the etiology remains unknown. We aimed to evaluate the fibroblasts and histological alterations to give new clues.
Bullon, Pedro +3 more
core +1 more source

