Results 51 to 60 of about 4,991 (245)

Curcumin inhibits TGF-β1-induced connective tissue growth factor expression through the interruption of Smad2 signaling in human gingival fibroblasts

Journal of the Formosan Medical Association, 2018
Background/Purpose: Many fibrotic processes are associated with an increased level of transforming growth factor-β1 (TGF-β1). TGF-β1 can increase synthesis of matrix proteins and enhance secretion of protease inhibitors, resulting in matrix accumulation.
Jung-Tsu Chen, Chen-Ying Wang, Min-Huey Chen   +2 more
doaj   +1 more source

Drug-Induced Gingival Overgrowth - A Review

, 1970
Drug-induced gingival overgrowth is a side effect associated with 3 types of drugs: anticonvulsants (phenytoin), immunosuppressive agents (cyclosporine A), and various calcium channel blockers for cardiovascular diseases.
Zia Mamoon, Afrin Bintal Ali, Shaheen Lipika Quayum, Mst Fatema Akhter   +3 more
core   +1 more source

Comparison of Long vs. Short Concave Neck in One‐Piece Implants Inserted 1 mm Subcrestally: A Pre‐Clinical In Vivo Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives The aim was to assess the influence of one‐piece implant concave neck height on soft‐ and hard‐tissue healing on a canine model. Material and Methods Monoblock implants with a transgingival concave neck were randomly inserted 1 mm subcrestally.
Hadi Antoun, Frank Bonnet, María Permuy Mendaña, Daniele Botticelli, Giovanna Iezzi, Morena Petrini   +5 more
wiley   +1 more source

Amlodipine induced gingival enlargement

Journal of Oral Research and Review, 2016
Drug-induced gingival overgrowth or enlargement is an abnormal growth of the gingiva due to an adverse drug reaction in patients treated with anticonvulsants, immunosuppressants, and calcium channel blockers (CCBs).
Shankar Gittaboyina, Thirumalesh Kothakota Mana, Rekha Rani Koduganti, P Veerendra Nath Reddy   +3 more
doaj   +1 more source

The Complex World of Toothpaste Diversity, Meeting Patient Clinical Needs. An Umbrella Review

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Background Amidst numerous recent advancements in toothpaste formulations and active ingredients, some clinicians may believe all toothpastes are similar despite differences in their active ingredients and corresponding clinical application.
Jeanie Suvan, Crystal Marruganti
wiley   +1 more source

Effect of concomitant administration of nifedipine and tacrolimus on the development of gingival overgrowth in rats

Journal of Dental Sciences, 2015
Background/purpose: It is still controversial whether tacrolimus can induce gingival overgrowth. Calcium channel blockers of nifedipine are commonly used for lessening the side effect of high blood pressure induced by tacrolimus; however, nifedipine can ...
Sheng-Yi Chen, Cheng-Yang Chiang, Yu-Wen Yeh, Hsiao-Pei Tu, Hsien-Chung Chiu, Shin Nieh, Earl Fu   +6 more
doaj   +1 more source

Mechanism of Azithromycin Treatment on Gingival Overgrowth

Journal of Dental Research, 2008
Azithromycin is effective for the remission of cyclosporine A-induced gingival overgrowth (CIGO) in persons who have undergone renal transplant. To explain its mechanism in alleviating the clinical symptoms of these indivduals, we examined the effect of azithromycin on cell proliferation and collagen turnover modified by cyclosporin A in human gingival
J-Y, Kim, S-H, Park, K-S, Cho, H-J, Kim, C-K, Lee, K-K, Park, S-H, Choi, W-Y, Chung   +7 more
openaire   +3 more sources

Prevention of Phenytoin-Induced Gingival Overgrowth by Lovastatin in Mice

, 2015
Drug-induced gingival overgrowth is caused by the antiseizure medication phenytoin, calcium channel blockers, and ciclosporin. Characteristics of these drug-induced gingival overgrowth lesions differ.
Sume, Siddika S., Trackman, Philip C., Assaggaf, Mohammad A., Kantarci, Alpdogan   +3 more
core   +1 more source

Efficacy and Safety of an Innovative Intraoral Cleaning Device—A Randomized Controlled Clinical Trial

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Objective This two‐centre, double‐blind, randomized, parallel‐group study compared the efficacy and safety of a novel powered full‐mouth cleaning device system (FMCD) with habitual toothbrushing (CG) in patients with generalized gingivitis over 6 weeks.
Tim Steuber, Christian Graetz, Claudia Springer, Simone Sutor, Tobias Hahn, Elfriede Fritzer, Christof E. Dörfer, Sonja Sälzer   +7 more
wiley   +1 more source

Multiple External Invasive Root Resorption and Calcification in Systemic Sclerosis—Case Report

International Endodontic Journal, EarlyView.
ABSTRACT Aim There are few reports in the literature of multiple external invasive root resorption (EIRR) lesions in patients with systemic sclerosis (SSc), and an association between root resorption and SSc is not well established. We report the only case that comprehensively illustrates—with the combination of histopathology, cone beam computed ...
Jee‐Yun Leung, Geoffrey Heithersay, Richard Logan, Sharon Liberali   +3 more
wiley   +1 more source