Results 71 to 80 of about 4,991 (245)

CORRELATION OF BLOOD LEVELS OF CYCLOSPORINE AND IT'S METABOLITES AND LOCAL FACTORS WITH GINGIVAL OVERGROWTH IN IRANIAN RENAL ALLOGRAFT PATIENTS

Acta Medica Iranica, 1997
Forty renal allograft patients with three months under immunosuppression by cycloserine were examined for their gingival overgrowth and it's correlation with several parameters including the trough levels of blood cyclosporine and it's metabolites ...
M. Sahebjamee ., A.R. Dehpour ., M. Davarmanesh ., F. Azordegan ., M. Abbasi M. Lesan Pezeshki   +4 more
doaj  

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Mechanism of Ciclosporin-induced gingival hyperplasia An in vitro study of the effect of ciclosporin on human gingival fibroblasts and oral keratinocytes

, 2011
PhDObjectives: Ciclosporin (CsA) is a potent and effective immuno-suppressive drug, but its use is associated with the development of gingival hyperplasia in up to 70% of patients.
Hanino, Mohammad
core  

Elevated Interleukin-17A expression in amlodipine-induced gingival overgrowth

, 2020
Background and objectives Amlodipine, a calcium channel blocker derivative, is frequently used by patients with high blood pressure. Studies reported that it can induce gingival overgrowth.
Yagmur Ilarslan, Ezel Berker, Siddika Selva Sume, GÜLTEKİN, SİBEL ELİF, Gultekin, Sibel E., Ilarslan, Yagmur, BERKER, Ayşe Ezel, Yucel, Ozlem Ozer, Goyushov, Samir, Goyusov, Samir, Samir Goyushov, Ozlem Ozer Yucel, Berker, Ezel, Cagman Tan, Ilhan Tezcan, Tan, Cagman, Sibel E. Gultekin, Tezcan, Ilhan, Ozer Yucel, Ozlem, Sume, Siddika Selva   +19 more
core   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

A Case Report of a Gingival Plasma Cell Granuloma in a Patient on Antihypertensive Therapy: Diagnostic Enigma

Frontiers in Dentistry, 2019
The aim of the present report was to discuss a unique case of gingival plasma cell granuloma (PCG) in a hypertensive patient on Amlodipine therapy. Also, we attempt to emphasize the importance of considering primary and advance investigations before ...
Ruchi Gulati, Madhu Singh Ratre, Shaleen Khetarpal, Manish Varma   +3 more
doaj   +1 more source

Epithelial to mesenchymal transition in human gingival overgrowth [PDF]

, 2011
Thesis (MSD) --Boston University, Henry M. Goldman School of Dental Medicine, 2011 (Department of Oral Biology and Periodontology).Includes bibliographic references: leaves 66-78.Drug induced gingival overgrowth is a side-effect and unwanted outcome of ...
Kim, Yong Soo
core  

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

Down-regulation of miR-200b-targeting Slug axis by cyclosporine A in human gingival fibroblasts

Journal of the Formosan Medical Association, 2018
Background/Purpose: Cyclosporine A (CsA) has been used as an immunosuppressive agent with a side effect of gingival overgrowth. It has been known that CsA-induced epithelial-mesenchymal transition (EMT) in gingiva, but the molecular mechanism has not ...
Taichen Lin, Cheng-Chia Yu, Pei-Ling Hsieh, Yi-Wen Liao, Chuan-Hang Yu, Chun-Jung Chen   +5 more
doaj   +1 more source

Drug-Induced Gingival Overgrowth

Journal of International College of Dentists
Tungare S, Paranjpe AG.
europepmc   +2 more sources