Results 121 to 130 of about 70,116 (226)
Etoposide, an anticancer drug that inhibits topoisomerase II, is commonly used in combination chemotherapy. However, the impact of O‐GlcNAcylation regulation on etoposide's anticancer effects has rarely been investigated.
Jaehoon Lee +5 more
doaj +1 more source
Obesity and Natural Products: Mechanisms, Therapeutic Potential, and Future Directions
Natural products such as EGCG, berberine, curcumin, and capsaicin modulate key metabolic pathways including AMPK activation, adipogenesis inhibition, and inflammatory signaling. While clinical trials demonstrate modest benefits on body weight and metabolic parameters, translational challenges related to bioavailability, dose feasibility, and regulatory
Ohoud M. Marie +1 more
wiley +1 more source
Analysis of Ginsenoside Isomers by Inlet Ionization-High Resolution Mass Spectrometry
The ginsenoside isomers were analyzed and distinguished by using inlet ionization-high resolution mass spectrometry technology under positive and negative ion modes with optimum inlet temperatures.
Yun-long GUO +7 more
doaj +1 more source
Comparing the effects of alcoholic extract of ginseng with itraconazole against Candida albicans and Candida krusei [PDF]
Background: Candidiasis is a prevalent disease which is caused by different species of Candida. Herbal drugs (e.g. ginseng) were traditionally administrated for the treatment of different diseases.
Kazemi, A., Nowrozi, H., Tajik-Ijdan, F.
core +1 more source
Exercise and dietary polyphenols enhance hippocampal plasticity and cognitive function via complementary molecular mechanisms. Central pathways include BDNF signaling, inflammation control, and mitochondrial regulation. Although synergy is mainly supported by preclinical data, lifestyle‐based strategies show promise for brain health maintenance ...
Zhenyi Zhao, Sima‐sadat Sabihi
wiley +1 more source
Ginsenoside Rb1 Targets the HRD1‐STING Axis to Mitigate Cholesterol‐Induced VSMC Senescence
Schematic representation of the proposed mechanism of action for Ginsenoside Rb1. Suppression of HRD1 expression in VSMCs cholesterol stimulation, leading to ER stress (BiP/XBP1s upregulation), STING pathway activation, ROS accumulation (including mitochondrial ROS), and ultimately, VSMC senescence.
Haiming Niu +5 more
wiley +1 more source
Common respiratory diseases. [PDF]
The self-medication phenomenon in upper respiratory tract infections, rhinosinusitis, asthma, and chronic obstructive pulmonary disease are significant and will continue to increase.
Kilgore, David, Najm, Wadie
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ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound vesicles released by any cell type under both physiological and pathological conditions. They carry a wide array of bioactive molecules, including microRNAs (miRNAs), lipids, proteins and other small biomolecules, and therefore play a key role in intercellular communication by ...
Tamer Esmail +20 more
wiley +1 more source
The combinational effect of cardiac and biochemical markers in diabetic patients with cardiovascular disease [PDF]
Background: Clinicopathological correlations, as well as several angiographic studies, suggest that diabetic patients have more extensive atherosclerotic disease, affecting the coronary arteries in particular.
Palanisamy Pasupathi, YY Rao, Farook J, Sathiyamoorthy Subramaniyam, Babu Shankar Ponnusha, Athimoolam Ambika, Int J Cur Bio Med Sci.
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