Results 141 to 150 of about 41,073 (260)
Fatty Acid Metabolism in Health and Cancer: From Fundamental Mechanisms to Therapeutic Application
The modulation of the TME by fatty acid metabolism primarily occurs through four key pathways: inflammation regulation, signal transduction, translation to TME, and oxidative stress. ABSTRACT Fatty acid metabolism (FAM) plays a vital role in maintaining health by supporting energy production, cellular structure, and signaling processes.
Na Hang +12 more
wiley +1 more source
Ginseng consumption and risk of cancer: A meta-analysis
BackgroundThe findings of currently available studies are not consistent with regard to the association between the risk of cancer and ginseng consumption.
Jia, Xiao-bin +11 more
core +1 more source
Encephalopathy: Cause, Pathogenesis, and Treatment
Various encephalopathies (sepsis‐associated, hepatic, hypoxic–ischemic, diabetic, uremic, toxic) have incompletely elucidated pathogenesis, which severely restricts targeted therapy development. Small molecule drugs show unique multitarget potential but face toxicity, poor blood–brain barrier penetration and unclear specificity.
Shimeng Lv +7 more
wiley +1 more source
Effectiveness of korean red ginseng in male erectile dysfunction
Ginseng has been used in maintaining physical vitality throughout the far-eastern countries and recently its metabolism and actions on neurologic, cardiovascular, and endocrinologic systems are studied.
최영득
core
ABSTRACT Tolvaptan is widely used as an adjunct oral diuretic to loop and thiazide diuretics for the management of fluid overload in patients with congestive heart failure. Recently, tolvaptan sodium phosphate (TSP), a water‐soluble prodrug of tolvaptan, was developed for intravenous administration and has demonstrated efficacy and safety in clinical ...
Takaya Uno +10 more
wiley +1 more source
ABSTRACT Kaempferol has been shown to be beneficial in the treatment of Alzheimer's disease (AD) in animal models. However, the action mechanism remains unclear. AKR1B1 has been identified as a target of kaempferol, initially suggested by the Therapeutic Target Database, DrugBank, and PubChem, and subsequently confirmed through experimental validation.
Le Li +5 more
wiley +1 more source
Effects of biogas residue addition, as cultivation substrate, on ginseng growth
The effects of biogas residue as a substrate on ginseng growth and its feasibility for ginseng cultivation are unclear. The present study used biogas residue at different concentrations and maturity levels to cultivate ginseng.
Zhijie Qiu +5 more
core +1 more source
Emerging Treatments for Erectile Dysfunction
ABSTRACT Erectile dysfunction (ED) is a prevalent condition that can significantly affect men's sexual health and quality of life, and for which there are many well‐studied effective treatments. In spite of this, many individuals still seek out alternative therapies.
Resa Magill +3 more
wiley +1 more source
Analytical development for analysis of American ginseng and multiple agriculturual chemicals from soil [PDF]
Ginseng has been used for thousands of years as an herbal remedy for many common ailments. Ginsenosides from ginseng have shown a wide range of biological effects, including antioxidant and anti-cancer properties.
Conine, Michael B. +1 more
core
This study investigated spexin in high‐glucose–induced insulin‐resistant C2C12 myotubes, focusing on its ability to modulate insulin‐signaling pathways and the glucose transporter GLUT4. These findings highlight spexin's potential role in improving peripheral insulin sensitivity by regulating key molecular targets involved in glucose homeostasis ...
Ann Sze Cheah +3 more
wiley +1 more source

