Results 41 to 50 of about 87,692 (274)

Cholesterol-modulating effects of Korean red ginseng (KRG) targeting PCSK9 in hyperlipidemia

Scientific Reports
Hyperlipidemia represents a major global health concern, closely linked to cardiovascular disease (CVD) and metabolic syndrome. Effective regulation of blood lipid and cholesterol (CHO) is essential for preventing and managing this condition.
Chang Hwan Lee, Yong Yook Lee, Jin Sun Jung, Sun Hee Hyun, Jaehoon Lee, Ji-Hye Park, Soo Kyung Park, Seung Ho Lee   +7 more
doaj   +1 more source

UHPLC-MS-Based Serum and Urine Metabolomics Reveals the Anti-Diabetic Mechanism of Ginsenoside Re in Type 2 Diabetic Rats

Molecules, 2021
Panax ginseng was employed in the treatment of “Xiao-Ke” symptom, which nowadays known as diabetes mellitus, in traditional Chinese medicine for more than a thousand years. Ginsenoside Re was the major pharmacologic ingredient found abundantly in ginseng.
Heyu Wang, Yaran Teng, Shinan Li, Ying Li, Hui Li, Lili Jiao, Wei Wu   +6 more
doaj   +1 more source

Complementary music therapy for cancer patients in at-home palliative care and their caregivers: protocol for a multicentre randomised controlled trial [PDF]

, 2020
Background Patients with advanced cancer, receiving at-home palliative care, are subject to numerous symptoms that are changeable and often require attention, a stressful situation that also impacts on the family caregiver.
Barón López, Francisco Javier, Casals Vázquez, Cristina, Espinar Toledo, Milagrosa, Martínez Valero, Francisco Javier, Valero Cantero, Inmaculada, Vázquez Sánchez, María Ángeles   +5 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Ginseng-derived nanoparticles induce skin cell proliferation and promote wound healing

Journal of Ginseng Research, 2023
Background: Past studies suggested that ginseng extracts and ginseng-derived molecules exerted significant regulatory effects on skin. However, no reports have described the effects of ginseng-derived nanoparticles (GDNPs) on skin cell proliferation and ...
Song Yang, Shuyan Lu, Limei Ren, Shuai Bian, Daqing Zhao, Meichen Liu, Jiawen Wang   +6 more
doaj   +1 more source

Microneedle‐Based Biofertilizer Delivery Improves Plant Growth Through Microbiome Engineering

Advanced Functional Materials, EarlyView.
This figure shows how microneedles are used to deliver biofertilizers to enhance plant growth through microbial migration, metabolic reprogramming, and changes in plant endogenous microbiome. Abstract This study presents a microneedle‐based system for the delivery of rhizospheric biofertilizers into plant tissues to enhance growth.
Zhicheng Le, Sevugan Mayalagu, Cheng‐Yen Chen, Raktim Bhattacharya, Abhishek Gupta, Jingyuan Li, Zhi Wei Norman Teo, Yufeng Shou, Arya Gopinath MP, Danni Zhong, Tedrick Thomas Salim Lew, Hao Yu, Naweed I. Naqvi, Sanjay Swarup, Andy Tay   +14 more
wiley   +1 more source

Simultaneous determination and difference evaluation of 14 ginsenosides in Panax ginseng roots cultivated in different areas and ages by high-performance liquid chromatography coupled with triple quadrupole mass spectrometer in the multiple reaction–monitoring mode combined with multivariate statistical analysis

Journal of Ginseng Research, 2019
Background: Ginsenosides are not only the principal bioactive components but also the important indexes to the quality assessment of Panax ginseng Meyer. Their contents in cultivated ginseng vary with the growth environment and age.
Yang Xiu, Xue Li, Xiuli Sun, Dan Xiao, Rui Miao, Huanxi Zhao, Shuying Liu   +6 more
doaj   +1 more source

Pharmacogenomics and the Yin/Yang actions of ginseng: anti-tumor, angiomodulating and steroid-like activities of ginsenosides. [PDF]

, 2007
In Chinese medicine, ginseng (Panax ginseng C.A. Meyer) has long been used as a general tonic or an adaptogen to promote longevity and enhance bodily functions.
Cheng, Yuen Kit, Fan, David Tai Ping, Leung, Kar Wah, Mak, Nai Ki, Ng, Tzi Bun, Wong, Ricky Ngok Shun, Yeung, Hin Wing, Yue, Patrick Ying Kit   +7 more
core   +1 more source

Acute and Chronic Effects of Green Oat (Avena sativa) Extract on Cognitive Function and Mood during a Laboratory Stressor in Healthy Adults: A Randomised, Double-Blind, Placebo-Controlled Study in Healthy Humans [PDF]

, 2020
Green oat (Avena sativa) extracts contain several groups of potentially psychoactive phytochemicals. Previous research has demonstrated improvements in cognitive function following a single dose of these extracts, but not following chronic ...
Bonnländer, Bernd, Forster, Joanne, Jackson, Philippa, Kennedy, David, Khan, Julie, Lang, Stefanie C., Pischel, Ivo, Wightman, Emma   +7 more
core   +2 more sources