Results 51 to 60 of about 30,545 (193)

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

Precision Medical Sciences, EarlyView.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

American Ginseng Acutely Regulates Contractile Function of Rat Heart

Frontiers in Pharmacology, 2014
Chronic ginseng treatments have been purported to improve cardiac performance. However reports of acute administration of ginseng on cardiovascular function remain controversial and potential mechanisms are not clear.
Mao eJiang, Mao eJiang, Juan M Murias, Tom eChrones, Stephen M Sims, Stephen M Sims, Edmund eLui, Edmund eLui, Earl G Noble, Earl G Noble   +9 more
doaj   +1 more source

Cancer Vaccine Development: Toward Artificial Intelligence‐Assisted Personalized Cell Membrane Nanovaccine

Small, EarlyView.
Cancer nanovaccines have emerged as promising alternatives to conventional cancer vaccines, which have shown limited clinical efficacy. In particular, cell membrane nanoparticle‐based nanovaccines can offer high biocompatibility and immunogenicity while preserving tumor antigens, including antigen repertoires.
Munsik Kim, Ilkoo Noh
wiley   +1 more source

miR‐522 facilitates the prosperities of endometrial carcinoma cells by directly binding to monoamine oxidase B

Kaohsiung Journal of Medical Sciences, 2019
It is well known that microRNAs (miRNAs) are crucial regulatory factors in tumorigenesis, as tumor suppressors or cancer‐promoting factors. However, the study of endometrial carcinoma relevance in miR‐522 is rare, indicating an undefined molecular ...
Hong‐Chang Zhang, Yan‐Yan Han, Xin‐Min Zhang, Nan Xiao, Tao Jiang, Shuang Zhu, En‐Peng Wang, Chang‐Bao Chen   +7 more
doaj   +1 more source

Risks of alcohol–energy drink co‐consumption: Patterns, correlates and psychological outcomes in youth

The American Journal on Addictions, EarlyView.
Abstract Background and Objectives This study examined the prevalence of alcohol mixed with energy drinks (AmED) among Spanish adolescents and young adults and analyzed its associations with sociodemographic factors, substance use, and mental health.
Roberto Secades‐Villa, Clara Iza‐Fernández, Ángel García‐Pérez, Layla Alemán‐Moussa, Alba González‐Roz   +4 more
wiley   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

A new lanostane-type triterpene with lipid-lowering activity from Ganoderma lucidum and an additional analogue

Frontiers in Chemistry
Non-alcoholic fatty liver disease (NAFLD) represents a chronic liver disorder with widespread global prevalence, primarily attributed to hepatic lipid accumulation, oxidative stress, and inflammatory responses.
Xuesheng Hu, Lu Han, Yiying Tan, Peitong Wu, Yajing Li, Wanjie Liu, Jiaming Shen, Yishan Li, Ming Yang, Chunnan Li, Jiaming Sun   +10 more
doaj   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Protective effects of extracellular vesicle‐like nanoparticles derived from Cannabis sativa adventitious roots against UVB‐induced damage in human keratinocytes

International Journal of Cosmetic Science, EarlyView.
Cannabis sativa root‐derived extracellular vesicle‐like nanoparticles (CA‐NPs) were isolated from adventitious root cultures and subjected to physicochemical characterization. Upon UVB exposure, keratinocytes exhibited increased ROS generation, apoptosis and MAPK activation, leading to oxidative stress and skin damage.
Dong Ho Bak, Su Hyun Park, Young Bae Ryu, Cha Young Kim, Jae Cheol Jeong, Woo Sik Kim   +5 more
wiley   +1 more source