Results 161 to 170 of about 6,513 (215)
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Ginsenoside Rg1 and ginsenoside Rh1 prevent liver injury induced by acetaminophen in mice
Journal of Food Biochemistry, 2021With the development of technology, drugs are being developed for different purposes. Thus, the rate of drug injury considerably increased worldwide. Liver is the largest detoxification organ in the human body, but it is also the organ most vulnerable to drug damage.
Yunfeng Bi +5 more
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Ginsenoside Rg1 modulates PI3K/AKT pathway for enhanced osteogenesis via GPER.
Phytomedicine, 2023BACKGROUND Osteoporosis is a systemic skeletal disorder characterized by decreased bone density and the degradation of bone tissue microarchitecture. Ginsenoside Rg1, derived from Panax ginseng, has been a part of traditional Chinese medicine in China ...
Zhongjing Jiang +5 more
semanticscholar +1 more source
Current Medicinal Chemistry, 2023
INTRODUCTION Sepsis-induced acute kidney injury is related to an increased mortality rate by modulating ferroptosis through ginsenoside Rg1. In this study, we explored the specific mechanism of it.
Jun Guo, Long Chen, Min Ma
semanticscholar +1 more source
INTRODUCTION Sepsis-induced acute kidney injury is related to an increased mortality rate by modulating ferroptosis through ginsenoside Rg1. In this study, we explored the specific mechanism of it.
Jun Guo, Long Chen, Min Ma
semanticscholar +1 more source
Chemical Biology and Drug Design, 2022
Alzheimer's disease (AD) is a chronic neurodegenerative disorder that can cause cognitive impairment. Ginsenoside Rg1 (Rg1) has a significant neuroprotective effect on animals with memory impairment.
Yi Yang +7 more
semanticscholar +1 more source
Alzheimer's disease (AD) is a chronic neurodegenerative disorder that can cause cognitive impairment. Ginsenoside Rg1 (Rg1) has a significant neuroprotective effect on animals with memory impairment.
Yi Yang +7 more
semanticscholar +1 more source
Journal of Leukocyte Biology, 2022
Acute kidney injury (AKI) represents a prevailing complication of sepsis, and its onset involves ferroptosis. Ginsenoside Rg1 exerts a positive effect on kidney diseases. This study explored the action of ginsenoside Rg1 in sepsis‐induced AKI (SI‐AKI) by
Jun Guo, Rong Wang, Fei Min
semanticscholar +1 more source
Acute kidney injury (AKI) represents a prevailing complication of sepsis, and its onset involves ferroptosis. Ginsenoside Rg1 exerts a positive effect on kidney diseases. This study explored the action of ginsenoside Rg1 in sepsis‐induced AKI (SI‐AKI) by
Jun Guo, Rong Wang, Fei Min
semanticscholar +1 more source
Phytomedicine, 2023
BACKGROUND Ischemic stroke, a severe and life-threatening neurodegenerative condition, currently relies on thrombolytic therapy with limited therapeutic window and potential risks of hemorrhagic transformation.
Junpeng Long +14 more
semanticscholar +1 more source
BACKGROUND Ischemic stroke, a severe and life-threatening neurodegenerative condition, currently relies on thrombolytic therapy with limited therapeutic window and potential risks of hemorrhagic transformation.
Junpeng Long +14 more
semanticscholar +1 more source
The American Journal of Chinese Medicine, 2006
Enzyme-linked immunosorbent assay (ELISA) systems using anti-ginsenoside Rb1 (G-Rb1) and Rg1 (G-Rg1) monoclonal antibodies (MAbs) were established for pharmacokinetic investigations of G-Rb1 and G-Rg1 in rat serum. The systems not only allowed sensitive detection of G-Rb1 at the level as low as 20 ng/ml and of G-Rg1 at 300 ng/ml, but showed strong ...
Zhi, Chao +2 more
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Enzyme-linked immunosorbent assay (ELISA) systems using anti-ginsenoside Rb1 (G-Rb1) and Rg1 (G-Rg1) monoclonal antibodies (MAbs) were established for pharmacokinetic investigations of G-Rb1 and G-Rg1 in rat serum. The systems not only allowed sensitive detection of G-Rb1 at the level as low as 20 ng/ml and of G-Rg1 at 300 ng/ml, but showed strong ...
Zhi, Chao +2 more
openaire +2 more sources
Phytotherapy Research, 2023
Diabetic cardiomyopathy (DCM) is a cardiac complication resulting from long‐term uncontrolled diabetes, characterized by myocardial fibrosis and abnormal cardiac function.
Juan Zhen +4 more
semanticscholar +1 more source
Diabetic cardiomyopathy (DCM) is a cardiac complication resulting from long‐term uncontrolled diabetes, characterized by myocardial fibrosis and abnormal cardiac function.
Juan Zhen +4 more
semanticscholar +1 more source
Ginsenoside Rg1 prevent and treat inflammatory diseases: A review
International Immunopharmacology, 2020Ginseng has been used as reinforcing drugs or for traditional Chinese medicine in aging, inflammation, stress, diabetes mellitus, hepatic diseases and cancer. The aim of this current review is to provide an integrative overview of the uses, relative human diseases and related mechanisms of ginseng.
Yan, Gao +8 more
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Biotechnology Letters, 2012
Ginsenosides Re and Rg1 were transformed by recombinant β-glucosidase (Bgp1) to ginsenosides Rg2 and Rh1, respectively. The bgp1 gene consists of 2,496 bp encoding 831 amino acids which have homology to the glycosyl hydrolase families 3 protein domain.
Lin-Hu, Quan +5 more
openaire +2 more sources
Ginsenosides Re and Rg1 were transformed by recombinant β-glucosidase (Bgp1) to ginsenosides Rg2 and Rh1, respectively. The bgp1 gene consists of 2,496 bp encoding 831 amino acids which have homology to the glycosyl hydrolase families 3 protein domain.
Lin-Hu, Quan +5 more
openaire +2 more sources