Results 171 to 180 of about 6,513 (215)
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Ginsenoside Rg1 attenuates glomerular fibrosis by inhibiting CD36/TRPC6/NFAT2 signaling in type 2 diabetes mellitus mice.

Journal of Ethnopharmacology, 2022
ETHNOPHARMACOLOGICAL RELEVANCE Ginsenoside Rg1 (Rg1) is one of the main active components in Panax ginseng C. A. Meyer (ginseng), which has been widely used to delay senescence or improve health conditions for more than 2000 years.
Yu-Ze Han   +8 more
semanticscholar   +1 more source

Ginsenoside Rg1 alleviates lipopolysaccharide-induced pyroptosis in human periodontal ligament cells via inhibiting Drp1-mediated mitochondrial fission.

Archives of Oral Biology, 2023
OBJECTIVE The present study aimed to investigate whether Ginsenoside Rg1 alleviated lipopolysaccharide (LPS) - induced pyroptosis of human periodontal ligament cells (HPDLCs) and further explore the underlying mechanism.
Kefei Chu   +5 more
semanticscholar   +1 more source

Ginsenoside Rg1 activates brown adipose tissue to counteract obesity in high-fat diet-fed mice by regulating gut microbes and bile acid composition.

Food & Function, 2023
Obesity is a global health problem strongly linked to gut microbes and their metabolites. In this study, ginsenoside Rg1 (Rg1) reduced lipid droplet size and hepatic lipid accumulation by activating uncoupling protein 1 expression in brown adipose tissue
Yize Liu   +12 more
semanticscholar   +1 more source

Ginsenoside Rg1 promotes proliferation of hippocampal progenitor cells

Neurological Research, 2004
Neural progenitor cells (NPCs) exist not only in the developing brain, but also in certain areas in adult brain in mammals. Recent studies suggest that promoting neurogenesis in adult mammals might provide a therapeutic way to cure age-related neurodegenerative diseases.
Li-Hong, Shen, Jun-Tian, Zhang
openaire   +2 more sources

Neuroprotective Effects and Brain Transport of Ginsenoside Rg1

Chinese Journal of Natural Medicines, 2009
Aim Ginsenoside Rg1, one of the major ingredients of Panax notoginseng saponins (PNS), has been proven to possess protective effects on the central nerve system (CNS). However, whether ginsenoside Rg1 could efficiently be transported through the blood brain barrier to elicit its neuroprotective effects remains still unclear. The present study was thus
Rui WANG   +5 more
openaire   +2 more sources

Ginsenoside Rg1 improved learning and memory ability and reduces neuronal apoptosis in epileptic rats through ERK/CREB/BDNF signal pathway.

Biochemical and Biophysical Research Communications - BBRC, 2023
OBJECTIVE This research was devoted to estimating the outcomes of ginsenoside Rg1 on learning and memory ability and neuronal apoptosis in epileptic rats through ERK/CREB/BDNF pathway.
Jiawei Zhang   +5 more
semanticscholar   +1 more source

Ginsenoside Rg1 inhibits platelet activation and arterial thrombosis

Thrombosis Research, 2014
Derived from the root of Panax ginseng C.A.Mey, Panax notoginsenosides (PNS) is a widely used herbal medicine to treat atherothrombotic diseases in Asian medicine. Ginsenoside Rg1 is one of the main compounds responsible for the pharmaceutical actions of PNS.
Qi, Zhou   +9 more
openaire   +2 more sources

Ginsenoside Rg1 attenuates lipopolysaccharide-induced chronic liver damage by activating Nrf2 signaling and inhibiting inflammasomes in hepatic cells.

Journal of Ethnopharmacology
ETHNOPHARMACOLOGICAL RELEVANCE Ginseng (Panax ginseng C. A. Meyer) is a precious traditional Chinese medicine with multiple pharmacological effects. Ginsenoside Rg1 is a main active ingredient extracted from ginseng, which is known for its age-delaying ...
Hui-Lan Zhou   +9 more
semanticscholar   +1 more source

Modification and stability of ginsenoside Rg1 PEG

China Journal of Chinese Materia Medica, 2012
OBJECTIVE To study the stability of ginsenoside Rg1 before and after being modified by PEG (PEG-Rg1) in isolated rat stomachs. METHOD SD rats, after 18 h of fasting, were randomly divided into the Rg1 group and the PEG-Rg1 group. Rg1 stomach perfusion fluid and PEG-Rg1 infusion fluid were accurately extracted and injected into their stomachs in vitro ...
openaire   +1 more source

Ginsenoside Rg1 alleviates chronic inflammation-induced neuronal ferroptosis and cognitive impairments via regulation of AIM2 - Nrf2 signaling pathway.

Journal of Ethnopharmacology
ETHNOPHARMACOLOGICAL RELEVANCE Ginseng is a valuable herb in traditional Chinese medicine. Modern research has shown that it has various benefits, including tonifying vital energy, nourishing and strengthening the body, calming the mind, improving ...
L. Kong   +9 more
semanticscholar   +1 more source

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