Results 191 to 200 of about 6,513 (215)

[Pharmacokinetics of ginsenosides Rg1 and Re in Shenmai injection].

Yao xue xue bao = Acta pharmaceutica Sinica, 2006
To study the pharmacokinetics of ginsenosides Rg1 and Re after iv infusion of Shenmai injection in human.Ginsenosides Rg1 and Re in plasma were determined by LC/MS/MS and the pharmacokinetic parameters were calculated.The linear regressive curves were obtained in the range of 1.023-1023 microg x L(-1) for Rg1 and 1.05-1050 microg x L(-1) for Re ...
Yi-ming, Liu, Liu, Yang, Xing, Zeng, Yuan-hui, Deng, Yi, Feng, Wei-xiong, Liang   +5 more
openaire   +1 more source

Optimization of combinations of ginsenoside-Rg1, ginsenoside-Rb1, evodiamine and rutaecarpine for effective therapy of mouse migraine

Journal of Natural Medicines, 2015
Wuzhuyu decoction (WZYD) is a classic traditional Chinese medicine (TCM) formula. It has been extensively used for treating migraine for thousands of years in TCM. Four potential active ingredients from WZYD, ginsenoside-Rg1 (Rg1), ginsenoside-Rb1 (Rb1), evodiamine (Ev) and rutaecarpine (Ru), were found to have positive correlations with ...
Yanchuan, Wu, Xueqiang, Pan, Yongsong, Xu, Xuran, Lu, Shida, He, Rui, He, Muxin, Gong   +6 more
openaire   +2 more sources

[Pharmacokinetics of ginsenosides Rg1 and its metabolites in rats].

Yao xue xue bao = Acta pharmaceutica Sinica, 2012
To study the pharmacokinetics of ginsenosides Rg1 and its metabolites after iv and oral administration in Wistar rats, the LC-MS/MS method was selected to determine ginsenosides Rg1 and its metabolites in plasma and their pharmacokinetic parameters were calculated.
Liang, Feng, Chang-Jiang, Hu, Ling-Ying, Yu   +2 more
openaire   +1 more source

[Research on the transformation of ginsenoside Rg1 by intestinal flora].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2003
The decomposition of Ginsenoside Rg1(Rg1) by intestinal bacteria in rats or human was investigated both in vitro and in vivo.The decompositions were investigated by means of thin-layer chromatography and Electron spurt ion mass.It was found that Rg1 was converted into two metabolites [Rh1 and 20(S)-protopanaxatriol(20S-Ppt)] by human intestinal ...
Y, Wang, T H, Liu, W, Wang, B X, Wang
openaire   +1 more source

Feasibility study of ginsenoside Rg1 administrated via intranasal route

China Journal of Chinese Matera Medica, 2010
To study the feasibility of ginsenoside Rg1 administrated from nasal route.The safty of ginsenoside Rg1 was evaluated by testing cilia movement of the in situ toad palate model. The stability of ginsenoside Rg1 to nasal enzymes and pH was evaluated by HPLC method.
openaire   +2 more sources

Ginsenoside Rg1 Prevents Doxorubicin-Induced Cardiotoxicity through the Inhibition of Autophagy and Endoplasmic Reticulum Stress in Mice

International Journal of Molecular Sciences, 2018
Zhi-Meng Xu, Ping Li
exaly  

Ginsenoside Rg1 Prevents PTSD-Like Behaviors in Mice Through Promoting Synaptic Proteins, Reducing Kir4.1 and TNF-α in the Hippocampus

Molecular Neurobiology, 2020
Juan Wang, Guoqi Zhu, Zhu Guoqi
exaly  

Antidepressant‐like effects of ginsenoside Rg1 are due to activation of the BDNF signalling pathway and neurogenesis in the hippocampus

British Journal of Pharmacology, 2012
Bo Jiang, Zhe Xiong, Zhuang-Li Hu
exaly  

Ginsenoside-Rg1, one of the major active molecules from Panax ginseng, is a functional ligand of glucocorticoid receptor

Molecular and Cellular Endocrinology, 1997
Kwang Youl Lee, Yong Hee Lee, Seung Ki Lee   +2 more
exaly  

Ginsenoside Rg1 promotes cerebral angiogenesis via the PI3K/Akt/mTOR signaling pathway in ischemic mice

European Journal of Pharmacology, 2019
Xiangjian Zhang, Xiaoxia Liu, Renhao Xu   +2 more
exaly