Results 121 to 130 of about 25,297 (234)

MicroRNAs in Methamphetamine: Addiction, Neurotoxicity, and Therapeutic Potential

MedComm – Future Medicine, Volume 5, Issue 1, March 2026.
The use of METH leads to the release of dopamine from the affected brain regions, including the nucleus accumbens (NAc), ventral tegmental area (VTA), prefrontal cortex (PFC), hippocampus (Hip), and striatum. This triggers signals that alter miRNA expression, which in turn leads to differential expression of target genes.
Yacoubou Abdoul Razak Mahaman, An‐Ping Ye, Ya‐Xian Zhang, Ming‐Yu Chen, Fang Huang, Rong Liu, Ying‐Yan Fang, Xiaochuan Wang   +7 more
wiley   +1 more source

Review of Amino Acid Foliar Application as a Stress Mitigation Strategy: Unraveling the Protective Mechanisms Against Abiotic Stress

Journal of Sustainable Agriculture and Environment, Volume 5, Issue 1, March 2026.
ABSTRACT The foliar application of amino acids offers a promising strategy to mitigate multiple abiotic stresses—drought, salinity, heat and heavy metals—by enhancing plant physiological, biochemical and molecular responses. This review synthesises recent advances in understanding how external amino acids function as bio‐stimulants, focusing on ...
Xiaoyu Ma, Mirezhatijiang Kayoumu, Yue Yin, Zewen Wang, Guilan Duan   +4 more
wiley   +1 more source

Transcriptional regulation of human NMNAT2: insights from 3D genome sequencing and bioinformatics

The FEBS Journal, Volume 293, Issue 5, Page 1433-1458, March 2026.
NMNAT2 is a valuable drug target, as low levels increase the risk of neurodegeneration. We employed 4C‐seq to identify NMNAT2 regulatory regions in the human genome, revealing distinct interactomes of the NMNAT2 promoter in undifferentiated and neuron‐like SH‐SY5Y cells. Additionally, we uncovered NMNAT2‐associated genes and transcription factors. This
Yu Chen Chang, Sen Yang, Minyoung Cho, Kwangsik Nho, José‐Manuel Baizabal, Hui‐Chen Lu   +5 more
wiley   +1 more source

Impact of combined ginsenoside‐MC1 and irisin on mitochondrial apoptosis in diabetic rats with hepatic reperfusion injury: Role of AMPK/JNK signalling

Experimental Physiology, Volume 111, Issue 3, Page 751-764, 1 March 2026.
Abstract Hepatic ischaemia–reperfusion (IR) injury is a serious clinical issue, especially in patients with type 2 diabetes mellitus (T2DM). As mitochondria play a critical role in the regulation of IR‐induced liver damage, mitochondria‐targeted treatment is of the utmost significance for improving outcomes.
Jie Lin, Lei Han, Zhigang Ma, Bo Yuan, Yabin Yu   +4 more
wiley   +1 more source

Exploring the allelopathic autotoxicity mechanism of ginsenosides accumulation under ginseng decomposition based on integrated analysis of transcriptomics and metabolomics

Frontiers in Bioengineering and Biotechnology
Continuous cropping obstacles seriously constrained the sustainable development of the ginseng industry. The allelopathic autotoxicity of ginsenosides is the key “trigger” of continuous cropping obstacles in ginseng.
Rui Wang, Tingting Zhou, Yikai Wang, Jinxu Dong, Yutao Bai, Xin Huang, Changbao Chen   +6 more
doaj   +1 more source

Evaluation of Ginsenosides and Their Derivatives From <i>Panax ginseng</i> as Aromatase Inhibitors for Breast Cancer Treatment-An <i>in silico</i> study. [PDF]

Biomed Res Int
Madhan JG, Sekaran S, Akshaya RN, Venkatesan K, Kirupanandasamy K, Vijayakumar K, Jenifer N, Paul BC.   +7 more
europepmc   +1 more source

RETRACTION: Ginseng and Its Active Components Ginsenosides Inhibit Adipogenesis in 3T3-L1 Cells by Regulating MMP-2 and MMP-9. [PDF]

Evid Based Complement Alternat Med
And Alternative Medicine EC.
europepmc   +1 more source

Preventive and therapeutic effects of ginsenosides on myocardial ischemia-reperfusion injury in animal models: a systematic review and meta-analysis. [PDF]

BMC Cardiovasc Disord
Yue H, Jia Y, Sun R, Song Z, Li W.
europepmc   +1 more source

Antibodies as Tools for Characterization, Isolation and Production Enhancement of Anti-Cancer Drugs and Steroidal Hormones from Ginsenoside and Solasodine Glycoside: A Review. [PDF]

Antibodies (Basel)
Shoyama Y.
europepmc   +1 more source

In silico identification of bilobetin and ginsenoside as dual CK2 and ULK2 inhibitors targeting triple-negative breast cancer. [PDF]

Sci Rep
Hossain MA, Tamanna IJ, Hossain MS, Parvez A, Afrin S, Sobuj DR, Islam MT, Al Noman A, Ahmed M, Sultana S, Srivastava S, Rao GSNK, Khan SR, Babu MR, Tariq M, Saiyad MT, Hamzah Z, Jain M.   +17 more
europepmc   +1 more source