Results 101 to 110 of about 15,696 (249)
Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.ABSTRACT Kaempferol has been shown to be beneficial in the treatment of Alzheimer's disease (AD) in animal models. However, the action mechanism remains unclear. AKR1B1 has been identified as a target of kaempferol, initially suggested by the Therapeutic Target Database, DrugBank, and PubChem, and subsequently confirmed through experimental validation.
Le Li +5 more
wiley +1 more source
Regulated Cell Death in Idiopathic Pulmonary Fibrosis
The FASEB Journal, Volume 40, Issue 9, 15 May 2026.This graphical abstract illustrates regulated cell death (RCD) across key pulmonary cell types—including alveolar epithelial cells, fibroblasts, macrophages, and endothelial cells—modulated through a dynamic death modulation network within the IPF microenvironment.
Xiaoyue Pan +10 more
wiley +1 more source
Ginsenosides act as positive modulators of P2X4 receptors [PDF]
, 2018 We investigated the selectivity of protopanaxadiol ginsenosides from Panax ginseng acting as positive allosteric modulators on P2X receptors. ATP-induced responses were measured in stable cell lines overexpressing human P2X4 using a YOPRO-1 dye uptake ...
Asatryan +23 more
core +3 more sources
Advanced Science, Volume 13, Issue 25, 4 May 2026.This study presents a DNA hydrogel‐mediated delivery system, in which ginsenoside (GS) molecules are incorporated into small extracellular vesicles (sEV) secreted by mesenchymal stem cells (MSCs) and the formed complexes are then anchored in DNA hydrogels via aptamer‐CD63 affinity as “GS/sEV@DNAgels”, to improve diabetic wound repair.
Jianming Xing +14 more
wiley +1 more source
Non-clinical pharmacokinetic behavior of ginsenosides
Journal of Ginseng Research, 2019 Ginsenosides, the major active ingredients of ginseng and other plants of the genus Panax, have been used as natural medicines in the East for a long time; in addition, their popularity in the West has increased owing to their various beneficial ...
Hyo-Joong Won +12 more
doaj +1 more source
Division of Biofunctional Evaluation(Research Center for Ethomedicine) [PDF]
, 2006 この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されまし
佐藤 亜希子 +2 more
core +2 more sources
Panax ginseng C.A Meyer root extract for moderate Chronic Obstructive Pulmonary Disease (COPD): study protocol for a randomised controlled trial [PDF]
, 2011 Background: Chronic obstructive pulmonary disease (COPD) impairs quality of life and leads to premature mortality. COPD sufferers experience progressive deterioration of lung function and decreased ability to undertake day-to-day activities.
Anthony L Zhang +7 more
core +1 more source
Advanced Science, Volume 13, Issue 25, 4 May 2026.Diabetic Wound Healing This cover highlights an aptamer‐functionalized DNA hydrogel (GS/sEV@DNAgel) forming hexagonal networks that precisely capture and immobilize ginsenoside‐loaded extracellular vesicles. The DNA‐engineered scaffold achieves controlled vesicle retention and sustained drug release through its programmable architecture, effectively ...
Jianming Xing +14 more
wiley +1 more source
Antiallergic Activity of Ginsenoside Rh2
Biological & Pharmaceutical Bulletin, 2003 The antiallergic activities of ginsenosides, which were isolated from acid-treated ginseng (Panax ginseng, Araliaceae), and their metabolites by human intestinal bacteria were measured. Ginsenoside Rh2, which is a main metabolite, had the most potent inhibitory activity on beta-hexosaminidase release from RBL-2H3 cells and in the passive cutaneous ...
Eun-Kyung, Park +4 more
openaire +3 more sources
Cancer Reports, Volume 9, Issue 5, May 2026.ABSTRACT Background Bladder cancer (BCa) is the most common and representative type of adult urinary tract urothelial cancer, characterized by high incidence and mortality rates. It has become a major disease threatening public health, highlighting the urgent need for the development of comprehensive treatment strategies, including traditional Chinese ...
Di Liu, Qing‐Yu Zhang
wiley +1 more source