Results 121 to 130 of about 11,938 (227)

Gasdermin‐Mediated Pyroptosis: Novel Strategies Against Colorectal Cancer

Cancer Science, Volume 117, Issue 8, Page 2064-2084, August 2026.
Pyroptosis is a double‐edged sword in colorectal cancer (CRC): chronic low‐grade pyroptosis promotes tumor progression, whereas acute induction of pyroptosis in cancer cells triggers antitumor immunity and enhances therapeutic response. Targeting gasdermin‐mediated pyroptosis represents a promising strategy for CRC treatment.
Kaibo Guo, Yuqian Feng, Jiamin Lu, Nuerbiye Abudurexiti, Xinlei Zhou, Mengfan Wei, Song Zheng   +6 more
wiley   +1 more source

MicroRNAs mediate the anti-tumor and protective effects of ginsenosides [PDF]

, 2019
MicroRNAs (miRs(, as short non-coding RNAs, regulate important biological processes and mainly are associated with regulation of gene expression. The miRs are beneficial targets for diagnosis of various disorders, particularly cancer, since their ...
Mohammadinejad, R., Farkhondeh, T., Ahmadi, Z., Ashrafizadeh, M., Samarghandian, S.   +4 more
core  

Ginsenosides Extracted from Nanoscale Chinese White Ginseng Enhances Anticancer Effect [PDF]

, 2012
Ginsenosides, the major chemical composition of Chinese white ginseng (Panax ginseng C. A. Meyer), can inhibit tumor, enhance body immune function, prevent neurodegeneration.
Yanxia Ji, Chunying Chen, Jinlei Cui, Ziyu Rao, Jian Ru Gong, Chunying Shu, Fondren Library, Haiying Bao   +7 more
core  

Biotransformation of Ginsenoside Rb1 to Ginsenoside Rd and 7 Rare Ginsenosides Using Irpex lacteus with HPLC-HRMS/MS Identification

ACS Omega
The biotransformation of ginsenosides using microorganisms represents a promising and ecofriendly approach for the production of rare ginsenosides. The present study reports on the biotransformation of ginsenoside Rb1 using the fungus Irpex lacteus, resulting in the production of ginsenoside Rd and seven rare ginsenosides with novel structures ...
Yue Gao, Yadong Feng, Yanyan Chang, Zhu Zhu, Huanxi Zhao, Wei Xu, Mengya Zhao, Yusheng Xiao, Lu Tian, Yang Xiu   +9 more
openaire   +3 more sources

Positive allosteric modulator activity of ginsenosides is restricted to P2X7 and P2X4 receptors. [PDF]

Purinergic Signal
Allum E, Stokes L.
europepmc   +2 more sources

Ginsenosides C-Mc1 and C-O Unique to Wild Ginseng: Novel Senotherapeutic Agents to Regulate Cellular Senescence

Natural Product Communications
Background Senotherapeutics, agents targeting cellular senescence, have recently shown great promise in anti-aging applications by removing senescent cells or attenuating the senescence-associated secretory phenotype (SASP).
Dohyun Kim, Seongsu Kang, Seung-Hyun Jun, Nae-Gyu Kang   +3 more
doaj   +1 more source

Ginsenosides for the Management of Metabolic Dysfunction-Associated Fatty Liver Disease: A Research Update. [PDF]

Nutrients
Zhang K, Qin Z, Guo Q, Lu J, Luo H, Zha L.   +5 more
europepmc   +1 more source

Effects of Long-Term Administration of Ginsenosides on the Structure of Intestinal Microflora and the Absorption and Utilization of Saponins in Rats. [PDF]

Metabolites
Dou G, Bi X, Wang N, Li S, Huang Y, Lu S, Wang Z, Ji W, Hong Y, Dong W.   +9 more
europepmc   +1 more source

Ginsenosides: potential therapeutic agents against hepatic fibrosis. [PDF]

J Ginseng Res
Wu Z, Liu Y.
europepmc   +1 more source

Research Progress on the Mechanism of Ginsenosides in the Treatment of Parkinson's Disease. [PDF]

Int J Mol Sci
Wang S, Chen Z, Tang H, Gong J, Xu K, Wang K.   +5 more
europepmc   +1 more source