Results 41 to 50 of about 25,297 (234)

Microbial conversion of major ginsenosides in ginseng total saponins by Platycodon grandiflorum endophytes

Journal of Ginseng Research, 2016
Background: In this study, we screened and identified an endophyte JG09 having strong biocatalytic activity for ginsenosides from Platycodon grandiflorum, converted ginseng total saponins and ginsenoside monomers, determined the source of minor ...
Lei Cui, Song-quan Wu, Cheng-ai Zhao, Cheng-ri Yin   +3 more
doaj   +1 more source

Effects of gut microbiota on the pharmacokinetics of protopanaxadiol ginsenosides Rd, Rg3, F2, and compound K in healthy volunteers treated orally with red ginseng

Journal of Ginseng Research, 2020
Background: It is well recognized that gut microbiota is involved in the biotransformation of ginsenosides by converting the polar ginsenosides to nonpolar bioactive ginsenosides.
Jeon-Kyung Kim, Min Sun Choi, Woonhee Jeung, Jehyeon Ra, Hye Hyun Yoo, Dong-Hyun Kim   +5 more
doaj   +1 more source

Ginsenosides Rc, as a novel SIRT6 activator, protects mice against high fat diet induced NAFLD

Journal of Ginseng Research, 2023
Background: Hepatic lipid disorder impaired mitochondrial homeostasis and intracellular redox balance, triggering development of non-alcohol fatty liver disease (NAFLD), while effective therapeutic approach remains inadequate.
Zehong Yang, Yuanyuan Yu, Nannan Sun, Limian Zhou, Dong Zhang, HaiXin Chen, Wei Miao, Weihang Gao, Canyang Zhang, Changhui Liu, Xiaoying Yang, Xiaojie Wu, Yong Gao   +12 more
doaj   +1 more source

Biotransformation of major ginsenosides in ginsenoside model culture by lactic acid bacteria

Journal of Ginseng Research, 2017
Background: Some differences have been reported in the biotransformation of ginsenosides, probably due to the types of materials used such as ginseng, enzymes, and microorganisms.
Seong-Eun Park, Chang-Su Na, Seon-A Yoo, Seung-Ho Seo, Hong-Seok Son   +4 more
doaj   +1 more source

Changes of Ginsenoside Composition in the Creation of Black Ginseng Leaf

Molecules, 2020
Ginseng is an increasingly popular ingredient in supplements for healthcare products and traditional medicine. Heat-processed ginsengs, such as red ginseng or black ginseng, are regarded as more valuable for medicinal use when compared to white ginseng ...
Wei Chen, Prabhu Balan, David G. Popovich   +2 more
doaj   +1 more source

Classification of three types of ginseng samples based on ginsenoside profiles: appropriate data normalization improves the efficiency of multivariate analysis

Heliyon, 2022
Background: It is well known that ginsenosides are the main active ingredients in ginseng, and they have also been important indexes for assessing the quality of ginseng.
Yahui Li, Bingkun Yang, Wei Guo, Panpan Zhang, Jianghua Zhang, Jing Zhao, Qiao Wang, Wei Zhang, Xiaowei Zhang, Dezhi Kong   +9 more
doaj   +1 more source

Advances in the Production of Minor Ginsenosides Using Microorganisms and Their Enzymes

BIO Integration, 2020
Minor ginsenodes are of great interest due to their diverse pharmacological activities such as their anti-cancer, anti-diabetic, neuroprotective, immunomodulator, and anti-inflammatory effects. The miniscule amount of minor ginsenosides in ginseng plants
Almando Geraldi
doaj   +1 more source

Carbon nanodots constructed by ginsenosides and their high inhibitory effect on neuroblastoma

Journal of Nanobiotechnology, 2023
Background Neuroblastoma is one of the common extracranial tumors in children (infants to 2 years), accounting for 8 ~ 10% of all malignant tumors. Few special drugs have been used for clinical treatment currently.
Yingnan Jiang, Lizhi Xiao, Jifeng Wang, Tenghui Tian, Guancheng Liu, Yu Zhao, Jiajuan Guo, Wei Zhang, Jiawen Wang, Changbao Chen, Wenyi Gao, Bai Yang   +11 more
doaj   +1 more source

Effect of ginsenosides on microbial community and enzyme activity in continuous cropping soil of ginseng

Frontiers in Microbiology, 2023
Root exudates contain plant metabolites secreted by the roots into the soil, such as ginsenosides secreted by the ginseng root. However, little is known about ginseng root exudate and its impact on the chemical and microbial properties of soil.
Xinyue Miao, Ergang Wang, Yi Zhou, Yu Zhan, Ning Yan, Changbao Chen, Qiong Li   +6 more
doaj   +1 more source

Additive interaction of intrathecal ginsenosides and neostigmine in the rat formalin test [PDF]

Korean Journal of Anesthesiology, 2013
BackgroundThe authors evaluated the effect of intrathecal mixture of ginsenosides with neostigmine on formalin-induced nociception and made further clear the role of the spinal muscarinic (M) receptors on the activity of ginsenosides.MethodsA catheter ...
Cheon-Hee Park, Park-Ne Kim, Seong-Heon Lee, Myung Ha Yoon   +3 more
doaj   +1 more source