Results 51 to 60 of about 15,696 (249)

Selected ginsenosides of the prptopanaxdiol series are novel positive allosteric modulators of P2X7 receptors [PDF]

, 2015
Background and Purpose The P2X7 receptor is an ATP-gated ion channel predominantly expressed in immune cells and plays a key role in inflammatory processes.
Adinolfi, Adinolfi, Alexander, Alexander, Attele, Bartlett, Bhaskaracharya, Choi, Choi, Choi, Chotjumlong, Ferrari, Ham, Han, Hanley, Huang, Jung, Jursik, Kilkenny, Kim, Kim, Kumagai, Lee, Lee, Lee, Leung, Leung, Leung, Li, Mackenzie, McGrath, Nah, Noh, Norenberg, Nörenberg, Pawson, Rivera, Sanz, Scaglione, Sengupta, Song, Song, Song, Surprenant, Tomasinsig, Virginio, Zhang, Zhang, Zheng   +48 more
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

The glycaemic effects of single doses of Panax ginseng in young healthy volunteers [PDF]

, 2006
The results of two acute placebo-controlled, double-blind cross-over studies assessing the effect of Panax ginseng (G115) on blood glucose levels are reported.
Kennedy, David, Reay, Jonathon, Scholey, Andrew   +2 more
core   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Ginseng: A panacea linking East Asia and North America? [PDF]

, 2015
The Supplement title: The Art and Science of Traditional Medicine Part 3: The Global Impact of Traditional ...
Chang, IM, Choi, R, Fan, TP, Jia, W, Kim, YS, Wong, AST, Wong, RNS   +6 more
core  

Time‐Controlled Refrigerated Stem Cell Therapy Mitigates Scleroderma Fibrosis via Modulation of Mitochondrial Autophagy and Gut Metabolism

Advanced Science, EarlyView.
This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia, Chenfei Kong, Xiaoming Zhao, Naixu Shi, Jinlan Jiang, Ping Li   +5 more
wiley   +1 more source

American Ginseng Modifies 137Cs-Induced DNA Damage and Oxidative Stress in Human Lymphocytes [PDF]

, 2009
The multifold bioactive medicinal properties of ginseng have been closely linked to its antioxidative ability, which is related to its ginsenoside content.
Allison, Ron R., Johnke, Roberta M., Lee, Tung-Kwang, O'Brien, Kevin F., Sheng, Chao, Wang, Tao, Wang, Weidong   +6 more
core   +1 more source

Almond (Amygdalus communis L.) Peptides Improve Scopolamine‐Induced Learning and Memory Impairment in Mice

Food Safety and Health, EarlyView.
Figure Schematic showing the improvement of almond peptides on learning and memory impairment induced by scopolamine in mice. Almond peptides (APs) could improve the learning and memory in scopolamine‐induced mice by maintaining cholinergic system homeostasis and regulating Nrf2/Keap1 signaling pathway, via activating the Nrf2 transcription factor and ...
Xin Shang, Wenjing Gao, Caiyun Zhao, Bin Li, Jintian Guo, Jingteng Wang, Minwei Zhang, Yinghua Fu   +7 more
wiley   +1 more source

Dynamic changes of multi-notoginseng stem-leaf ginsenosides in reaction with ginsenosidase type-I

Journal of Ginseng Research, 2019
Background: Notoginseng stem-leaf (NGL) ginsenosides have not been well used. To improve their utilization, the biotransformation of NGL ginsenosides was studied using ginsenosidase type-I from Aspergillus niger g.848.
Yongkun Xiao, Chunying Liu, Wan-Teak Im, Shuang Chen, Kangze Zuo, Hongshan Yu, Jianguo Song, Longquan Xu, Tea-Hoo Yi, Fengxie Jin   +9 more
doaj   +1 more source

Neuroprotective effects of ginsenosides

Acta Neurobiologiae Experimentalis, 2006
Ginseng, the root of the Panax species, is a well-known herbal medicine. Traditionally it has been used in Korea, China and Japan for thousands of years. Nowadays it has become a popular and worldwide known health drug. Current scientific studies demonstrate in vivo and in vitro its beneficial effects in a wide range of pathological conditions such as ...
Wolf-Dieter, Rausch, Shu, Liu, Gabriele, Gille, Khaled, Radad   +3 more
openaire   +2 more sources