Panax ginseng as an adjuvant treatment for Alzheimer's disease
Journal of Ginseng Research, 2018 Longevity in medicine can be defined as a long life without mental or physical deficits. This can be prevented by Alzheimer's disease (AD). Current conventional AD treatments only alleviate the symptoms without reversing AD progression.
Hyeon-Joong Kim +7 more
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Journal of Ginseng Research, 2023 Background: Gintonin (GT), a Panax ginseng-derived lysophosphatidic acid receptor (LPAR) ligand, has positive effects in cultured or animal models for Parkinson's disease, Huntington's disease, and so on. However, the potential therapeutic value of GT in
Jong Hee Choi +4 more
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Journal of Ginseng Research, 2022 Background: Gintonin-enriched fraction (GEF), a non-saponin fraction of ginseng, is a novel glycolipoprotein rich in hydrophobic amino acids. GEF has recently been shown to regulate lipid metabolism and browning in adipocytes; however, the mechanisms ...
Heegu Jin +3 more
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Neuroprotective Effects of a Traditional Multi-Herbal Medicine Kyung-Ok-Ko in an Animal Model of Parkinson's Disease: Inhibition of MAPKs and NF-κB Pathways and Activation of Keap1-Nrf2 Pathway [PDF]
, 2018 Kyung-Ok-Ko (KOK), a traditional multi-herbal medicine, has been widely used in Oriental medicine as a restorative that can enforce vitality of whole organs and as a medicine that can treat age-related symptoms including lack of vigor and weakened ...
Ik-Hyun Cho +8 more
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Lysophosphatidic acid receptors (LPARs): potential targets for the treatment of neuropathic pain [PDF]
, 2016 Neuropathic pain can arise from lesions to peripheral or central nerve fibres leading to spontaneous action potential generation and a lowering of the nociceptive threshold. Clinically, neuropathic pain can manifest in many chronic disease states such as
O'Sullivan, Catherine +2 more
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Atypical formations of gintonin lysophosphatidic acids as new materials and their beneficial effects on degenerative diseases. [PDF]
J Ginseng ResFresh ginseng is prone to spoilage due to its high moisture content. For long-term storage, most fresh ginsengs are dried to white ginseng (WG) or steamed for hours at high temperature/pressure and dried to form Korean Red ginseng (KRG). They are further processed for ginseng products when subjected to hot water extraction/concentration under pressure.
Kim JH +10 more
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Model organisms for investigating the functional involvement of NRF2 in non-communicable diseases [PDF]
Funding Information: Research in the authors\u2019 laboratories is funded as follows: AIR and AC by the Spanish Ministry of Science, Innovation and Universities (PID2019-110061RB-I00, PID-2021-122766OB-100, PDC2021-121421-I00, PDC2022-133765-I00 ...
Buttari, Brigitta +27 more
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Biomolecules, 2020 Obesity is a major health concern and is becoming an increasingly serious societal problem worldwide. The browning of white adipocytes has received considerable attention because of its potential protective effect against obesity-related metabolic ...
Kippeum Lee +6 more
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How natural therapies can combat neoplastic disease by targeting key survival mechanisms and signaling pathways [PDF]
Plant extracts are increasingly becoming an answer to expensive, high-dose, synthesized chemotherapy, with milder side effects and easier accessibility. Many botanical plants contain active ingredients, such as terpenoids and alkaloids, which may combat ...
Barker, James +11 more
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Rethinking the Use of Antidepressants to Treat Alcohol Use Disorders and Depression Comorbidity: The Role of Neurogenesis [PDF]
, 2019 Patients with alcohol use disorders (AUDs) are frequently treated with antidepressant drugs (ADs), but clinical evidence of their efficacy is contradictory.
Alén, Francisco +4 more
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