Genome sequencing reveals the prevalence of Fabry disease-causing variants in Japan: Evidence from the Tohoku Medical Megabank. [PDF]
Susukita K +13 more
europepmc +1 more source
Cancer Cell Metastasis: From Molecular Mechanisms to Therapeutic Strategies
The schematic representation of intrinsic and extrinsic influences of cancer cell metastasis. Genomic evolution of metastatic tumor cells (MTCs) promotes their metastatic phenotypes and reconstruct the primary tumor microenvironment. During MTCs migration along different routes (blood circulation, lymphatic vessels, and perineuronal spaces), the ...
Yupeng Zhao +7 more
wiley +1 more source
Characterization of two key cytochrome P450 enzymes in <i>Isodon amethystoides</i> and <i>de novo</i> production of 3α,15β-dihydroxy-<i>ent-</i>kaurene in yeast. [PDF]
Chen Y +11 more
europepmc +1 more source
Advertisement - Join GLA to Save on Georgia Libraries Conference Registration [PDF]
GLQ, GLA
core +1 more source
ABSTRACT Objective Concurrent use of antidepressants, particularly cytochrome P450 2D6 (CYP2D6) inhibitors, may reduce tamoxifen bioactivation and effectiveness. However, the clinical significance of this potential interaction remains inconclusive. This study examined whether concurrent antidepressant use is associated with increased metastasis risk ...
Shaimaa Elshafie +4 more
wiley +1 more source
Fabry cardiomyopathy presenting as hypertrophic phenotype with left ventricular outflow tract obstruction: a case series. [PDF]
Hosyanto FF, Li Y, Luo S, Huang B.
europepmc +1 more source
ABSTRACT The Marias River flows from Glacier National Park through northcentral Montana, and into the Missouri River. Annual flows gradually declined from 1902 to 2024 (~3.2%/decade) and the 1952 Tiber Dam and Lake Elwell reservoir were operated to attenuate peak flows and stabilize downstream flows year‐round.
Stewart B. Rood, Lori A. Goater
wiley +1 more source
Tri-Parametric Assessment of α-Galactosidase A Activity, lysoGb3 and X-Inactivation Aids Genotype-Phenotype Categorization of Fabry Disease Female Patients. [PDF]
Kuchar L +13 more
europepmc +1 more source
The here presented compounds Rb3Ln[AsS4]2 with Ln = Gd–Ho represent an extension of the nonisotypic Rb3Ln[AsS4]2 series (Ln = La–Nd, Sm, Gd–Ho). The crystal structures of all representatives of this series contain one‐dimensional chains separated by Rb+ cations.
Katja Engel, Thomas Schleid
wiley +1 more source
Licensed and investigational TLR4 agonists as vaccine adjuvants: structural basis, clinical progress, and future directions. [PDF]
Zhou J +10 more
europepmc +1 more source

