Results 101 to 110 of about 5,635,835 (408)

Howden Moss: a study of vegetational history in Upper Teesdale [PDF]

open access: yes, 1976
The peat deposits at Howden Moss, Upper Teesdale, have been examined stratigraphically and pollen analytically. The present state of the bog in described and pollen diagrams are presented for three sites. The results show that peat formation had begun by
Simpson, Caroline Anne
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

The Middle Pleistocene Transition by frequency locking and slow ramping of internal period [PDF]

open access: yes, 2019
The increase in glacial cycle length from approximately $41$ to on average $100$ thousand years around $1$ million years ago, called the Middle Pleistocene Transition (MPT), lacks a conclusive explanation. We describe a dynamical mechanism which we call Ramping with Frequency Locking (RFL), that explains the transition by an interaction between the ...
arxiv   +1 more source

“The Astronomical Theory of the Glacial Period“ [PDF]

open access: yesNature, 1896
As it was my two letters which initiated the interesting and not unfruitful discussion now going on in your pages on the above subject, I think it right to say a few words in reply.
openaire   +3 more sources

Sea surface temperature changes in the southern California borderlands during the last glacial-interglacial cycle [PDF]

open access: yes, 1996
A variety of evidence suggests that average sea surface temperatures (SSTs) during the last glacial maximum in the California Borderlands region were significantly colder than during the Holocene.
Bandy   +52 more
core   +2 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Mudanças climáticas e impactos sócio-territoriais dos desastres glaciais na Cordilheira Branca, Peru

open access: yesConfins, 2020
This article discusses the history of natural disasters in the Cordillera Blanca, Peru, during the 1970–2011 period. The study analyzed general disaster data over this timeframe and more broadly about glacial disasters from 1725 to 2010 AD. Historically,
Anderson Ribeiro de Figueiredo   +3 more
doaj   +1 more source

III.—On the Cause of the Glacial Period [PDF]

open access: yesGeological Magazine, 1883
In concluding an article on “The Climate Controversy” in the Geol. Mag. for September and October, 1876, I observed (p.451) that it had long appeared to me that the “Glacial period proper” was due neither to a change in the earth’s axis, nor to any variation in the eccentricity of the earth’s orbit, nor to any changes in the distribution of land and ...
openaire   +2 more sources

Potential atmospheric impact of the Toba Mega‐Eruption ∼71,000 years ago [PDF]

open access: yes, 1996
An ∼6‐year long period of volcanic sulfate recorded in the GISP2 ice core about 71,100 ± 5000 years ago may provide detailed information on the atmospheric and climatic impact of the Toba mega‐eruption. Deposition of these aerosols occur at the beginning
Mayewski, Paul A.   +5 more
core   +3 more sources

Integrated Summer Insolation Forcing and 40,000-Year Glacial Cycles: The Perspective from an Ice-Sheet/Energy-Balance Model [PDF]

open access: yes, 2008
Although the origins of the 40,000-year glacial cycles during the early Pleistocene are readily attributed to changes in Earth's obliquity (also having a 40,000-year period), the lack of ice-volume variability at precession periods (20,000 years) is ...
Huybers, Peter, Tziperman, Eli
core   +1 more source

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