Results 71 to 80 of about 2,526,213 (304)

Loss of CYLD on Chromosome 16q Impairs Homologous Recombination and Genomic Stability Through TIRR Degradation

Advanced Science, EarlyView.
Chromosome 16q loss drives genomic instability through disruption of the CYLD–TIRR–53BP1 axis. CYLD preserves homologous recombination by stabilizing TIRR and limiting 53BP1 accumulation at DNA double‐strand breaks. CYLD deficiency redirects repair toward error‐prone non‐homologous end joining, promotes mutational burden and homologous recombination ...
Mingming Lu, Jialu Kang, Qi Ye, Zixi Wang, Lei Li, Yuzeshi Lei, Leihong Ye, Tianjie Liu, Bin Wang, Tao Liu, Shan Xu, Ke Wang, Yong Zhang, Jian Ma, Lei Li   +14 more
wiley   +1 more source

A Modular Synthesis of C5‐Sulfenyl Thiazoles via an Intermolecular Pummerer Rearrangement: An Underexplored Scaffold for Medicinal Chemistry

Angewandte Chemie, EarlyView.
Modular access to underexplored C5‐sulfenyl thiazoles via an intermolecular Pummerer rearrangement is reported. The methodology exhibits a broad functional group tolerance enabling the seamless design of trisubstituted thiazole cores bearing a sulfur handle for further elaboration.
Joe L. Smy, Theo C. Webb, Barnaby W. Greenland, S. Mark Roe, John Spencer, Storm Hassell‐Hart   +5 more
wiley   +2 more sources

Calving rate linearly dependent on sub-aerial terminus cliff height at tidewater glaciers around the Antarctic Peninsula

Annals of Glaciology
Calving is the process of ice loss through the breaking of ice from a glacier’s terminus. Ice-flow models describe calving in various ways, although no consensus exists on the optimal approach.
Richard Parsons, Sainan Sun, Gudmundur Hilmar Gudmundsson   +2 more
doaj   +1 more source

Kinematics and geomorphological changes of a destabilising rock glacier captured from close-range sensing techniques (Tsarmine rock glacier, Western Swiss Alps)

Frontiers in Earth Science, 2022
Accurately assessing landform evolution and quantifying rapid environmental changes are gaining importance in the context of monitoring techniques in alpine environments.
Sebastián Vivero, Sebastián Vivero, Hanne Hendrickx, Amaury Frankl, Amaury Frankl, Reynald Delaloye, Christophe Lambiel   +6 more
doaj   +1 more source

Spectral roughness of glaciated bedrock geomorphic surfaces: Implications for glacier sliding [PDF]

, 2000
A microroughness meter (MRM) was used to measure the high-frequency roughness of a number of geomorphic surfaces in the forefield of Glacier de Tsanfleuron, Switzerland.
Martin J. Siegert, Danny McCarroll, Hubbard, B., McCarroll, D., Bryn Hubbard, Siegert, M. J.   +5 more
core   +1 more source

Atmospheric Water Harvesting Through Polymer Hydrogel Sorbents: Materials Chemistry, Design Strategies, and Applications

Advanced Science, EarlyView.
Polymer‐based hydrogels have emerged as promising materials for atmospheric water harvesting (AWH) due to their high water affinity, tunable network structure, and excellent moisture adsorption‐desorption performance. Functional hydrogel systems enable efficient water capture and controlled release under low‐energy conditions, offering a sustainable ...
Swagata Datta, Sushmit Sen, Nilanjan Dey, Amrita Chatterjee, Ananya Sadhu, Sudipta Sarkar, Pradip K. Maji   +6 more
wiley   +1 more source

Sub-debris melt rates on southern Inylchek Glacier, central Tian Shan [PDF]

, 2008
Melt rates of glacier surfaces are strongly influenced by the existence of a debris cover. Dependent on thickness and other physical parameters the debris layer can enhance or reduce ablation as compared to bare ice conditions.
Lambrecht, Astrid, Wilfried Hagg, Christoph Mayer, Helm, Achim, Astrid Lambrecht, Mayer, Christoph, Hagg, Wilfried, Achim Helm   +7 more
core   +1 more source

Freestanding Hierarchical‐Porous BCZT Thin Films Enable Efficient Ultrasonic Energy Harvesting in Soft Tissue

Advanced Science, EarlyView.
Freestanding hierarchical‐porous BCZT thin films integrate a compliant porous surface with a dense piezoceramic backbone to balance mechanical reliability, voltage sensitivity, and acoustic coupling. The films enable stable wearable pulse‐wave monitoring and enhanced tissue‐coupled ultrasonic energy harvesting, offering a promising route toward soft ...
Zifan Li, Shengwei Gao, Wang Hong, Yuxin Chen, Yiyang Gu, Xu Wang, Chen Tang, Ying Hong, Xuemu Li, Xiaodong Yan, Yi Zheng, Yiming Liu, Junchen Liao, Biao Wang, Shiyuan Liu   +14 more
wiley   +1 more source

The distribution of basal motion beneath a High Arctic polythermal glacier [PDF]

, 2003
The longitudinal pattern of surface velocity of a large, predominantly colds polythermal glacier (John Evans Glacier, Ellesmere Island, Canada) was measured over summer and winter periods.
Nienow, Peter W., Copland, L, Nienow, P, Bingham, RG, Sharp, M.J., Bingham, Robert George, Copland, L., Copland, Luke, Bingham, R.G., Sharp, Martin J., Sharp, MJ, Nienow, P., Bingham, Robert G.   +12 more
core   +1 more source

Space Jam‐Ming: Generating Interstitial Space Using Fragmented Granular GelMA to Investigate Novel Paradigms of Cancer Metastasis

Advanced Science, EarlyView.
Microgels enable independent control of stiffness and interstitial space, overcoming limitations of conventional 3D hydrogels. Using fragmented gelatin methacryloyl microgels, we show that stiffness does not restrict non‐metastatic breast cancer growth, contrary to bulk hydrogels, and reveal the role of adherent‐to‐suspension transition in cancer ...
Danielle Vahala, Zhuang Min Lee, Sebastian E. Amos, Dong Woo Son, Jong Hwa Byun, Farzan Navaeipour, Jiayue Li, Kai L. Metzner, Ji Hoon Jeong, Juyeon Kim, Yongsung Hwang, Brendan F. Kennedy, Khoon S. Lim, Hee Seung Lee, Hyun Woo Park, Yu Suk Choi   +15 more
wiley   +1 more source