Results 81 to 90 of about 6,191 (305)

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Glacier Velocity Monitoring by Maximum Likelihood Texture Tracking [PDF]

IEEE Transactions on Geoscience and Remote Sensing, 2009
The performance of a tracking algorithm considering remotely sensed data strongly depends on a correct statistical description of the data, i.e., its noise model. The objective of this paper is to introduce a new intensity tracking algorithm for synthetic aperture radar (SAR) data, considering its multiplicative speckle/noise model.
Esra Erten, Andreas Reigber, Olaf Hellwich, Pau Prats   +3 more
openaire   +1 more source

High‐elevation endemic plants predicted to lose habitat from changing climate in Washington State

American Journal of Botany, EarlyView.
Abstract Premise High‐elevation plants face unique challenges from potential climate change impacts that will likely require upslope migration into increasingly smaller suitable habitat. This situation is particularly acute for endemic species that by definition occupy small geographic ranges.
Nicholas L. Gjording, Erik W. Ertsgaard, David E. Giblin, Iris H. Dimpsey, Owen B. Bard   +4 more
wiley   +1 more source

Interpreting a Legacy Fossil Assemblage Excavated From Waribruk (New Guinea II Cave), GunaiKurnai Aboriginal Country, Snowy River National Park, Southeastern Australia

Archaeology in Oceania, EarlyView.
ABSTRACT In this paper we report on faunal remains recovered from a legacy archaeological excavation undertaken in the rockshelter entrance of Waribruk (New Guinea II Cave), a GunaiKurnai site located on the west bank of the Snowy River, East Gippsland, southeastern Australia.
Matthew C. McDowell, Bruno David, Jean‐Jacques Delannoy, Russell Mullett, Fiona Petchey, Helen Green, Joanna Fresløv, GunaiKurnai Land and Waters Aboriginal Corporation   +7 more
wiley   +1 more source

Glacier speed-up as a possible precursor to volcanic eruptions at Mount Veniaminof, Alaska

Journal of Glaciology
Identifying early indicators of volcanic eruptions is a fundamental part of natural hazard management but is notoriously difficult. Here we consider whether monitoring changes in glacier velocity can help.
Michael Dieter Martin, Iestyn Barr, Benjamin Edwards, Matteo Spagnolo, Elias Symeonakis, Joseph Mallalieu, Kathryn Adamson, Donal Mullan, Maximillian Van Wyk de Vries   +8 more
doaj   +1 more source

Magnetoelastic Cell Monitoring System for Evaluating the Effects of Surface Chemistry on the Performance of Mesenchymal Stem Cell Growth

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The recent clinical adoption of cell therapies has increased the need for more efficient, robust, and reproducible manufacturing technologies. Human mesenchymal stromal cells (hMSCs), a major component of the cell and immunotherapeutic market, remain challenging to manufacture at scale because they require surface attachment and are highly ...
William S. Skinner, Carolina Rivera‐Crespo, Eyerusalem A. Gebreyesus, Said Cifuentes, Samantha Tan, Tristen Douglas, Maribella Domenech‐Garcia, Keat Ghee Ong   +7 more
wiley   +1 more source

A New Method for Automatic Glacier Extraction by Building Decision Trees Based on Pixel Statistics

Remote Sensing
Automatic glacier extraction from remote sensing images is the most important approach for large scale glacier monitoring. Commonly used band calculation indices to enhance glacier information are not effective in identifying shadowed glaciers and debris-
Xiao Liu, Hongyi Cheng, Jiang Liu, Xianbao Su, Yuchen Wang, Bin Qiao, Yipeng Wang, Nai’ang Wang   +7 more
doaj   +1 more source

Vertical profile reconstruction with Pol-InSAR data of a subpolar glacier

, 2007
The last decade has seen an increasing demand for accurate mapping and wide-coverage monitoring of glaciers and ice sheets in order to measure and predict their response to global climate change and their contribution to sea level rise.
Konstantinos P. Papathanassiou, Sharma, Jayanti, Hajnsek, Irena, Papathanassiou, Konstantinos, Jayanti J. Sharma, Irena Hajnsek   +5 more
core   +1 more source

InSAR observations of ice elevation and velocity fluctuations at the Flade Isblink ice cap, eastern North Greenland [PDF]

, 2010
The 8500 km(2) Flade Isblink ice cap (FIIC) (81 degrees 15'N, 15 degrees 0'W) is the largest ice cap in Greenland. We use repeat-pass interferometric synthetic aperture radar (InSAR) techniques to investigate the form and flow of the FIIC.
Rinnem, Eero, Nienow, Peter, Peter Nienow, Andrew Shepherd, Palmer, Steven J., Shepherd, Andrew, Eero Rinnem, Aud Sundal, Sundal, Aud, Steven J. Palmer   +9 more
core   +1 more source

A nanoplatform that induces dual‐amino acid deprivation to reverse tumor immunosuppression and enhance metabolic immunotherapy

BMEMat, EarlyView.
ZIF‐8‐based nanoparticles co‐delivering CB‐839 (glutaminase inhibitor) and 1‐MT (IDO1 inhibitor), dual‐targeting glutamine/tryptophan metabolism to induce immunogenic cell death, activate STING, block kynurenine production, reverse immunosuppression, and enhance cancer immunotherapy to suppress primary/distant tumors.
Wenli Ning, Yunhan Sun, Mingyang Li, Shilu Liu, Fangjie Yi, Hongfei Wang, Ruibing Bai, Dongdong Liu, Fen Zhao, Guiqiang Zhang, Xiao Fu   +10 more
wiley   +1 more source