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Glaesserella parasuis ClpX participates in stress tolerance and contributes to bacterial pathogenicity [PDF]

open access: yesMicrobiology Spectrum
The ClpX gene in bacteria, which plays a key role in adaptation to various environmental stresses, is associated with pathogenicity. However, its role in conferring external environmental stress resistance in Glaesserella parasuis remains unclear.
Manman Xu   +9 more
doaj   +5 more sources

Transcriptional profile of Glaesserella parasuis in swine serosal and joint fluids [PDF]

open access: yesFrontiers in Veterinary Science
Glaesserella parasuis is the causative agent of Glässer's disease and contributes to significant post-weaning mortality in the swine industry. Glässer's disease is characterized by meningitis, polyserositis, and polyarthritis.
Daniel W. Nielsen   +3 more
doaj   +4 more sources

Isolation and identification of two highly virulent Glaesserella parasuis serovar 7 strains in China [PDF]

open access: yesBMC Microbiology
Glaesserella parasuis (G. parasuis), the etiological agent of Glässer’ s disease, is a gram-negative bacterium and a common commensal in the upper respiratory tract of pigs, which can lead to fibrinous polyserositis, meningitis and polyarthritis. In this
Wang Zhendong   +4 more
doaj   +4 more sources

A novel function of RHOA as a host-dependent factor in Glaesserella parasuis infection of LLC-PK1 cells [PDF]

open access: yesVeterinary Research
Glaesserella parasuis (G. parasuis), a lethal pathogen causing Glässer’s disease, poses severe threats to global swine health. While the small GTPase Ras homolog gene family member A (RHOA) is implicated in viral pathogenesis, its role in bacterial ...
Huanhuan Zhou   +9 more
doaj   +2 more sources

Epidemiological and comparative genomic analysis of pathogenic Glaesserella parasuis from livestock agriculture in Shandong, China [PDF]

open access: yesFrontiers in Microbiology
Glaesserella parasuis (G. parasuis) is the causative agent of Glässer’s disease, posing a significant economic threat to the livestock agriculture. The present study aimed to investigate the prevalence of G.
Zetong Huang   +10 more
doaj   +2 more sources

LncRNA MEG3 Regulates Glaesserella parasuis-Induced Apoptosis of Porcine Alveolar Macrophages via Regulating ssc-miR-135/CASP8 Axis [PDF]

open access: yesMicroorganisms
Glaesserella parasuis (G. parasuis), a common pathogenic bacterium in the porcine respiratory tract, can cause porcine polyserositis, arthritis, and meningitis.
Yongchao Jia   +9 more
doaj   +2 more sources

Whole genome sequencing analyses of Chinese Glaesserella parasuis isolates reveal insights into their genomic characterization, virulence genes and antibiotic resistance genes [PDF]

open access: yesBMC Genomics
Background Glaesserella parasuis is a pathogen that frequently targets the upper respiratory tract of pigs, and it poses a considerable threat to the pig industry. The aim of this study is to enrich the genetic database of G.
Qi Sun   +12 more
doaj   +2 more sources

Antibacterial effects of cinnamaldehyde and hesperitin on resistant Glaesserella parasuis by suppressing QseBC two-component system [PDF]

open access: yesBMC Veterinary Research
Background Glaesserella parasuis (G. parasuis) is one of the most important porcine pathogens causing Glässer’s disease, and QseBC two-component system (TCS) is associated with various behaviors of G. parasuis.
Jingru Zuo   +8 more
doaj   +2 more sources

Cytolethal distending toxin from Glaesserella parasuis induces ferroptosis in porcine alveolar macrophages and mice [PDF]

open access: yesVeterinary Research
Glaesserella parasuis cytolethal distending toxin (GpCDT) is a bacterial genotoxin whose main action is to activate DNA damage responses, induce cell cycle arrest, and induce the apoptosis of host cells.
Shiyu Xu   +11 more
doaj   +2 more sources

Baicalin Relieves Glaesserella parasuis-Triggered Immunosuppression Through Polarization via MIF/CD74 Signaling Pathway in Piglets [PDF]

open access: yesBiomolecules
Glaesserella parasuis (G. parasuis) infection is responsible for Glässer’s disease in pigs. G. parasuis could trigger piglet immunosuppression, but the mechanism of inducing immunosuppression by G. parasuis remains unknown.
Shulin Fu   +9 more
doaj   +2 more sources

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