Results 31 to 40 of about 922 (163)

Assessment of the Macrophage Scavenger Receptor CD163 in Mediating Glaesserella parasuis Infection of Host Cells

Veterinary Sciences, 2023
The macrophage CD163 surface glycoprotein is a member of the SRCR family class B, which has been identified as the key trigger in host–pathogen interactions, but its specific roles in sensing Glaesserella parasuis (G.
Xiangwei Deng, Shuilian Li, Ying Zhu, Bo Yu, Jing Zhang, Qianhai Fang, Zhimin Li, Hongbo Chen, Huanhuan Zhou   +8 more
doaj   +2 more sources

Design of B-Cell Multi-Epitope Subunit Vaccines Against <i>Glaesserella parasuis</i> by Reverse Vaccinology: An In Silico and In Vivo Study. [PDF]

Transbound Emerg Dis
Glässer’s disease caused by Glaesserella parasuis (GPS) is a severe disease that results in substantial economic losses to the swine industry worldwide. Here we describe a multiepitope vaccine cocktail (MEVC) that was designed using reverse vaccinology and immunoinformatics. The MEVC was comprised of three multiepitope subunits (MESs, designated as TB,
Gong Y, Li N, Li Z, Wang H, Zhang D, Chu H, Lu Z, Jia A, Li F, Lei L.   +9 more
europepmc   +2 more sources

Pathotyping and molecular serotyping of clinical isolates of Glaesserella parasuis in Taiwan. [PDF]

Braz J Microbiol
Glaesserella parasuis is a bacterial pathogen that causes severe economic losses in the swine industry worldwide. In this study, 262 G. parasuis isolates from pigs with Glässer's disease obtained between 2015 and 2022 in Taiwan were serotyped, pathotyped, and analyzed for virulence genes. The most prevalent serovars were 5 (29%), 4 (27.9%), 12 (12.2%),
Lin WH, Yen CH, Yang CY, Lin CF, Chang YF, Lin CN, Chiou MT.   +6 more
europepmc   +3 more sources

Serotyping and Antimicrobial Susceptibility Profiling of Glaesserella parasuis Isolated from Diseased Swine in Brazil

Pathogens, 2022
Glaesserella parasuis is one of the major pathogens in swine intensive production systems. To date, 15 serovars have been described, and the prevalence of these serotypes in different geographical regions has been identified by several methods.
Givago Faria Ribeiro Silva, Luisa Zanolli Moreno, Carlos Emílio Cabrera Matajira, Ana Paula Santos Silva, Kawany Miyazaki Araújo, Vasco Túlio Moura Gomes, Mikaela Renata Funada Barbosa, Maria Inês Zanolli Sato, Andrea Micke Moreno   +8 more
doaj   +2 more sources

Upregulation of TLR4-Dependent ATP Production Is Critical for Glaesserella parasuis LPS-Mediated Inflammation

Cells, 2023
Glaesserella parasuis (G. parasuis), an important pathogenic bacterium, cause Glässer’s disease, and has resulted in tremendous economic losses to the global swine industry. G. parasuis infection causes typical acute systemic inflammation.
Fei Liu, Yidan Gao, Jian Jiao, Yuyu Zhang, Jianda Li, Luogang Ding, Lin Zhang, Zhi Chen, Xiangbin Song, Guiwen Yang, Jiang Yu, Jiaqiang Wu   +11 more
doaj   +2 more sources

Pleural thickening induced by Glaesserella parasuis infection was linked to increased collagen and elastin

Frontiers in Cellular and Infection Microbiology, 2022
Glaesserella parasuis is well-known for causing Glässer’s disease, which costs the worldwide swine industry millions of dollars each year. It has been reported the symptom of pleural thickening during Glässer’s disease but this symptom has received ...
Huimin Gong, Huimin Gong, Huimin Gong, Liying Chen, Liying Chen, Liying Chen, Yanling He, Yanling He, Yanling He, Kexin Hua, Kexin Hua, Kexin Hua, Bin Ma, Bin Ma, Bin Ma, Yuan Gao, Yuan Gao, Yuan Gao, Xiaojuan Xu, Xiaojuan Xu, Xueying Hu, Hui Jin, Hui Jin, Hui Jin   +23 more
doaj   +3 more sources

Baicalin Protects Vascular Tight Junctions in Piglets During Glaesserella parasuis Infection [PDF]

Frontiers in Veterinary Science, 2021
Glaesserella parasuis (G. parasuis) can cause Glässer's disease and severely affect swine industry worldwide. This study is an attempt to address the issue of the capability of G.
Yu Liu, Xiaoyi Li, Zhaoran Zhang, Jiacheng Zhang, Jianfeng Xu, Yinsheng Qiu, Chun Ye, Shulin Fu, Zhongyuan Wu, Chien-An Andy Hu   +9 more
doaj   +3 more sources

Pig nasal and rectal microbiotas are involved in the antibody response to Glaesserella parasuis. [PDF]

Sci Rep
Abstract Vaccination stands as one of the most sustainable and promising strategies to control infectious diseases in animal production. Nevertheless, the causes for antibody response variation among individuals are poorly understood. The animal microbiota has been shown to be involved in the correct development and function of the host ...
Obregon-Gutierrez P, Mahmmod Y, Barba-Vidal E, Sibila M, Correa-Fiz F, Aragón V.   +5 more
europepmc   +6 more sources

Deletion of Polyamine Transport Protein PotD Exacerbates Virulence in Glaesserella (Haemophilus) parasuis in the Form of Non-biofilm-generated Bacteria in a Murine Acute Infection Model

Virulence, 2021
Polyamines are small, polycationic molecules with a hydrocarbon backbone and multiple amino groups required for optimal cell growth. The potD gene, belonging to the ABC (ATP-binding cassette) transport system potABCD, encodes the bacterial substrate ...
Ke Dai, Yung-Fu Chang, Sanjie Cao
exaly   +2 more sources

A novel function of RHOA as a host-dependent factor in Glaesserella parasuis infection of LLC-PK1 cells [PDF]

Veterinary Research
Glaesserella parasuis (G. parasuis), a lethal pathogen causing Glässer’s disease, poses severe threats to global swine health. While the small GTPase Ras homolog gene family member A (RHOA) is implicated in viral pathogenesis, its role in bacterial ...
Huanhuan Zhou, Xuexue Chen, Xinqi Zeng, Shengsong Xie, Xiaoyu Zhang, Jiayi Zeng, Ke Xu, Bo Yu, Hailong Liu, Hongbo Chen   +9 more
doaj   +2 more sources