Results 51 to 60 of about 725 (132)

Dosing Regimen of Aditoprim and Sulfamethoxazole Combination for the Glaesserella parasuis Containing Resistance and Virulence Genes

Pharmaceutics, 2022
Glaesserella parasuis (G. parasuis) causes Glasser’s disease in pigs and causes high mortality in piglets. The new drug Aditoprim (ADP) alone or combined with Sulfamethoxazole (SMZ) is one of the good choices for treating respiratory infections.
Anxiong Huang, Xiao Huang, Zhihao Zhang, Zonghui Yuan, Lingli Huang, Yulian Wang, Yanfei Tao, Dongmei Chen, Zhenli Liu, Haihong Hao   +9 more
doaj   +1 more source

Baicalin inhibited PANX-1/P2Y6 signaling pathway activation in porcine aortic vascular endothelial cells infected by Glaesserella parasuis

Heliyon
Glaesserella parasuis can induce endothelial barrier damage in piglets, although the mechanism by which this pathogen triggers inflammatory damage remains unclear. Baicalin possesses anti-inflammatory and anti-oxidant activities.
Shulin Fu, Xinyue Tian, Chun Peng, Dan Zhang, Linglu Zhou, Yuzhen Yuan, Jing He, Ling Guo, Yinsheng Qiu, Chun Ye, Yu Liu, Bingbing Zong   +11 more
doaj   +1 more source

EspP2 Regulates the Adhesion of Glaesserella parasuis via Rap1 Signaling Pathway. [PDF]

Int J Mol Sci
Different levels of EspP2 expression are seen in strains of Glaesserella parasuis with high and low pathogenicity. As a potential virulence factor for G. parasuis, the pathogenic mechanism of EspP2 in infection of host cells is not clear. To begin to elucidate the effect of EspP2 on virulence, we used G. parasuis SC1401 in its wild-type form and SC1401,
Tang X, Xu S, Yang Z, Wang K, Dai K, Zhang Y, Hu B, Wang Y, Cao S, Huang X, Yan Q, Wu R, Zhao Q, Du S, Wen X, Wen Y.   +15 more
europepmc   +3 more sources

Genomic insight into the diversity of <i>Glaesserella parasuis</i> isolates from 19 countries. [PDF]

mSphere
ABSTRACT Glaesserella parasuis is a commensal bacterial organism found in the upper respiratory tract of healthy pigs and the etiological agent of Glässer’s disease, which causes severe economic losses in the swine industry.
Gong X, Cui Q, Zhang W, Shi Y, Zhang P, Zhang C, Hu G, Sahin O, Wang L, Shen Z, Fu M.   +10 more
europepmc   +4 more sources

Deletion of Polyamine Transport Protein PotD Exacerbates Virulence in Glaesserella (Haemophilus) parasuis in the Form of Non-biofilm-generated Bacteria in a Murine Acute Infection Model

Virulence, 2021
Polyamines are small, polycationic molecules with a hydrocarbon backbone and multiple amino groups required for optimal cell growth. The potD gene, belonging to the ABC (ATP-binding cassette) transport system potABCD, encodes the bacterial substrate ...
Ke Dai, Zhen Yang, Xiaoyu Ma, Yung-Fu Chang, Sanjie Cao, Qin Zhao, Xiaobo Huang, Rui Wu, Yong Huang, Jing Xia, Qigui Yan, Xinfeng Han, Xiaoping Ma, Xintian Wen, Yiping Wen   +14 more
doaj   +1 more source

Investigating the relationship between antimicrobial susceptibility and serovar of Glaesserella parasuis

, 2023
Abstract Background Glaesserella parasuis (G. parasuis) is the causative agent of Glässer’s disease and causes severe economic losses in the swine industry. Vaccination and antimicrobial therapy are crucial to Glässer’s disease prevention and control, and antimicrobial resistance (AMR) is an important issue.
Wei-Hao Lin, Cheng-Yao Yang, Chuen-Fu Lin, Chao-Nan Lin, Ming-Tang Chiou   +4 more
openaire   +1 more source

Rapid and simple detection of Glaesserella parasuis in synovial fluid by recombinase polymerase amplification and lateral flow strip

BMC Veterinary Research, 2019
Background Glaesserella parasuis (G. parasuis) is an influential pathogen of the pig, which induces high morbidity and mortality in naive pig populations in the pig industry. Accurate and rapid detection of the agent is important for disease control.
Ting-ting Zhang, Meng-zhi Liu, Rong-huan Yin, Long-quan Yao, Bao-shan Liu, Ze-liang Chen   +5 more
doaj   +1 more source

The Role of Antibodies Against the Crude Capsular Extract in the Immune Response of Porcine Alveolar Macrophages to In Vitro Infection of Various Serovars of Glaesserella (Haemophilus) parasuis

Frontiers in Immunology, 2021
In Glässer’s disease outbreaks, Glaesserella (Haemophilus) parasuis has to overcome the non-specific immune system in the lower respiratory tract, the alveolar macrophages.
Katarína Matiašková, Lenka Kavanová, Pavel Kulich, Jan Gebauer, Kateřina Nedbalcová, Hana Kudláčková, Radek Tesařík, Martin Faldyna, Martin Faldyna   +8 more
doaj   +1 more source

The molecular diversity of transcriptional factor TfoX is a determinant in natural transformation in Glaesserella parasuis

Frontiers in Microbiology, 2022
Natural transformation is a mechanism by which a particular bacterial species takes up foreign DNA and integrates it into its genome. The swine pathogen Glaesserella parasuis (G. parasuis) is a naturally transformable bacterium. The regulation of competence, however, is not fully understood. In this study, the natural transformability of 99 strains was
Xiaoyu Tang, Zhen Yang, Ke Dai, Geyan Liu, Yung-Fu Chang, Xinwei Tang, Kang Wang, Yiwen Zhang, Bangdi Hu, Sanjie Cao, Xiaobo Huang, Qigui Yan, Rui Wu, Qin Zhao, Senyan Du, Yifei Lang, Xinfeng Han, Yong Huang, Xintian Wen, Yiping Wen   +19 more
openaire   +3 more sources

PD-1/PD-L1 axis induced host immunosuppression via PI3K/Akt/mTOR signalling pathway in piglets infected by Glaesserella Parasuis

BMC Veterinary Research
Glaesserella parasuis, an important respiratory bacterial pathogen, causes Glässer’s disease in piglets, with potential immunosuppression. We established a piglet infection model and explored the immunosuppression mechanism to improve our understanding ...
Jingyang Li, Siyu Liu, Qiaoli Dong, Yunjian Fu, Yamin Sun, Ronghui Luo, Xinyue Tian, Ling Guo, Wei Liu, Yinsheng Qiu, Qirong Lu, Chun Ye, Bingbing Zong, Shulin Fu   +13 more
doaj   +1 more source