Results 61 to 70 of about 787 (149)

Evolutionary Origins and Virulence Determinants of ST25 Hypervirulent Klebsiella pneumoniae in Swine: Genomic Insights and Functional Validation

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The global spread of multidrug‐resistant hypervirulent Klebsiella pneumoniae (MDR‐HvKp), among which carbapenem‐resistant strains are of major concern, poses a severe threat to public health due to its high mortality rate and extremely limited treatment options.
Zheng Chen, Yang Liu, Congyang Du, Shengguo Gao, Lufeng Zhai, Stefan Schwarz, Weicheng Liu, Qiong Li, Longyu Li, Runhao Yu, Yuzhe Zhao, Hong Yao, Lei Luo, Xue Liu, Chunyan Xu, Xiang-Dang Du, Zongfu Wu   +16 more
wiley   +1 more source

The molecular diversity of transcriptional factor TfoX is a determinant in natural transformation in Glaesserella parasuis

Frontiers in Microbiology, 2022
Natural transformation is a mechanism by which a particular bacterial species takes up foreign DNA and integrates it into its genome. The swine pathogen Glaesserella parasuis (G. parasuis) is a naturally transformable bacterium. The regulation of competence, however, is not fully understood. In this study, the natural transformability of 99 strains was
Xiaoyu Tang, Zhen Yang, Ke Dai, Geyan Liu, Yung-Fu Chang, Xinwei Tang, Kang Wang, Yiwen Zhang, Bangdi Hu, Sanjie Cao, Xiaobo Huang, Qigui Yan, Rui Wu, Qin Zhao, Senyan Du, Yifei Lang, Xinfeng Han, Yong Huang, Xintian Wen, Yiping Wen   +19 more
openaire   +3 more sources

The Role of Antibodies Against the Crude Capsular Extract in the Immune Response of Porcine Alveolar Macrophages to In Vitro Infection of Various Serovars of Glaesserella (Haemophilus) parasuis

Frontiers in Immunology, 2021
In Glässer’s disease outbreaks, Glaesserella (Haemophilus) parasuis has to overcome the non-specific immune system in the lower respiratory tract, the alveolar macrophages.
Katarína Matiašková, Lenka Kavanová, Pavel Kulich, Jan Gebauer, Kateřina Nedbalcová, Hana Kudláčková, Radek Tesařík, Martin Faldyna, Martin Faldyna   +8 more
doaj   +1 more source

Development and Field Validation of a Double‐Antigen Sandwich Colloidal Gold Immunochromatographic Strip for Detection of Toxoplasma gondii Antibodies in Multiple Host Species

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Toxoplasmosis, a globally prevalent zoonosis caused by Toxoplasma gondii (T. gondii), poses major threats to both human and animal health, leading to reproductive losses in livestock and severe disease in immunocompromised individuals. Although enzyme‐linked immunosorbent assay (ELISA) and PCR are widely used for diagnosis and surveillance, they may be
Xin Mu, Chen Chen, Xianglin Pu, Lixin Xu, Mingmin Lu, Ruofeng Yan, Xiangrui Li, Xiaokai Song, Kamani Joshua   +8 more
wiley   +1 more source

The Quadruplex Real‐Time PCR Assay for Simultaneous Detection of GETV, PRRSV, JEV, and PCV2 in Swine

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
This study aimed to establish a quadruplex real‐time PCR assay for the simultaneous detection of Getah virus (GETV), Porcine reproductive and respiratory syndrome virus (PRRSV), Japanese encephalitis virus (JEV), and Porcine circovirus type 2 (PCV2).
Haojie Wang, Lihong Xue, Bowen Shan, Shuyan Wu, Tongqin An, Changqing Yu, Changyou Xia, He Zhang, Taotao Yang   +8 more
wiley   +1 more source

PD-1/PD-L1 axis induced host immunosuppression via PI3K/Akt/mTOR signalling pathway in piglets infected by Glaesserella Parasuis

BMC Veterinary Research
Glaesserella parasuis, an important respiratory bacterial pathogen, causes Glässer’s disease in piglets, with potential immunosuppression. We established a piglet infection model and explored the immunosuppression mechanism to improve our understanding ...
Jingyang Li, Siyu Liu, Qiaoli Dong, Yunjian Fu, Yamin Sun, Ronghui Luo, Xinyue Tian, Ling Guo, Wei Liu, Yinsheng Qiu, Qirong Lu, Chun Ye, Bingbing Zong, Shulin Fu   +13 more
doaj   +1 more source

Characterization and protective activity of monoclonal antibodies directed against Fe (3+) ABC transporter substrate-binding protein of Glaesserella parasuis

Veterinary Research, 2021
Glässer’s disease is caused by the agent Glaesserella parasuis and is difficult to prevent and control. Candidate screening for subunit vaccines contributes to the prevention of this disease. Therefore, in this study, the inactivated G.
Kexin Zhu, Dong Yu, Jiahui An, Yufeng Li
doaj   +1 more source

Generation of an Etiology Index Based on Confirmed Tissue Diagnosis Data to Assess Endemic Swine Etiology Activity in the United States of America

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Global pork production has increased substantially over the past few decades, making swine a critical source of animal protein. However, endemic diseases in pigs continue to pose significant challenges to animal health, productivity, and food security. Several etiologies affect farm‐level performance and have broader implications for zoonotic risks and
Guilherme A. Cezar, Danyang Zhang, Rodger G. Main, Eric R. Burrough, Rafael R. Nicolino, Maria Rodrigues da Costa, Gustavo Silva, Daniel C. L. Linhares, Giovani Trevisan, Kamani Joshua   +9 more
wiley   +1 more source

Effect of Vaccination against Glässer’s Disease in a Farm Suffering from Polyserositis in Weaned Pigs

Veterinary Sciences, 2022
Polyserositis mostly affects 4–8 weeks old piglets and is usually caused by Glaesserella parasuis, and/or Streptococcus suis, and/or Mycoplasma hyorhinis. The present study aimed to investigate the prevalence and etiology of polyserositis in a tricky pig
Jasmine Hattab, Giuseppe Marruchella, Abigail Rose Trachtman, Luigino Gabrielli, Nicola Bernabò, Francesco Mosca, Pietro Giorgio Tiscar   +6 more
doaj   +1 more source

Characterization of Pilin A and Thioredoxin A Mutant Strains of Acinetobacter baumannii, From a Transposon Insertion Library, for Pili Production and Virulence‐Associated Properties

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Acinetobacter baumannii transposon insertion mutant strains ΔpilA and ΔtrxA display marked reductions of surface pili. The PilA (a major pilin protein) and TrxA (thioredoxin A) deficient bacteria also show attenuation in pathogenesis including the reduction of intestinal bacterial attachment, increased phagocytic uptake and decreased mortality from ...
Jadelynn Aki, Sara B. Papp, Bayley Polk, Sean Jeffreys, Megan P. Tompkins, Anwar A. Kalalah, Mark Eppinger, Guoquan Zhang, M. N. Guentzel, James P. Chambers, Bernard P. Arulanandam, Jieh‐Juen Yu   +11 more
wiley   +1 more source