Results 61 to 70 of about 922 (163)

Deletion of two-component system QseBC weakened virulence of Glaesserella parasuis in a murine acute infection model and adhesion to host cells [PDF]

PeerJ, 2022
The widespread two-component system (TCS), QseBC, involves vital virulence regulators in Enterobacteriaceae and Pasteurellaceae. Here we studied the function of QseBC in Glaesserella parasuis. A ΔqseBC mutant was constructed using a Glaesserella parasuis
Xuefeng Yan, Ke Dai, Congwei Gu, Zehui Yu, Manli He, Wudian Xiao, Mingde Zhao, Lvqin He   +7 more
doaj   +2 more sources

Haemophilus parasuis (Glaesserella parasuis) as a Potential Driver of Molecular Mimicry and Inflammation in Rheumatoid Arthritis [PDF]

Frontiers in Medicine, 2021
Background:Haemophilus parasuis (Hps; now Glaesserella parasuis) is an infectious agent that causes severe arthritis in swines and shares sequence similarity with residues 261–273 of collagen type 2 (Coll261−273), a possible autoantigen in rheumatoid arthritis (RA).Objectives/methods: We tested the presence of Hps sequencing 16S ribosomal RNA in ...
Gabriele Di Sante, Elisa Gremese, Elisa Gremese, Barbara Tolusso, Paola Cattani, Paola Cattani, Clara Di Mario, Simona Marchetti, Stefano Alivernini, Maria Tredicine, Luca Petricca, Ivana Palucci, Ivana Palucci, Chiara Camponeschi, Virginia Aragon, Andrea Gambotto, Andrea Gambotto, Andrea Gambotto, Francesco Ria, Francesco Ria, Gianfranco Ferraccioli   +20 more
openaire   +6 more sources

Association between virulence genes and serovars, sequence types of glaesserella (haemophilus) parasuis isolates from the nasal cavity of live piglets [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi, 2022
Th is study analyzed the 19 virulence genes (VGs) of 117 Glaesserella (Haemophilus) parasuis (G. parasuis) isolates from the nasal cavities of live piglets from the south of China and assessed the associations between VGs and serovars, sequence types ...
Ling PENG, Di-yan LIANG, Jia-yuan CHEN, Ling-hui LI, Xiao-yan XI   +4 more
doaj   +1 more source

Baicalin Alleviates Piglet Immunosuppression Induced by Glaesserella parasuis via Promoting CD163/Tumor Necrosis Factor-like Weak Inducer of Apoptosis-Mediated Autophagy [PDF]

Biomolecules
Glaesserella parasuis (G. parasuis) causes vascular inflammation in piglets, resulting in vascular damage. However, the mechanism causing vascular inflammation remains unclear. Baicalin possesses an anti-inflammatory function.
Shulin Fu, Ronghui Luo, Jingyang Li, Yunjian Fu, Qiaoli Dong, Siyu Liu, Yamin Sun, Ling Guo, Jin Hu, Yinsheng Qiu   +9 more
doaj   +2 more sources

Development of a new multiplex quantitative PCR for the detection of Glaesserella parasuis, Mycoplasma hyorhinis, and Mycoplasma hyosynoviae [PDF]

, 2023
Glaesserella parasuis, Mycoplasma hyorhinis, and Mycoplasma hyosynoviae are important porcine pathogens responsible for polyserositis, polyarthritis, meningitis, pneumonia, and septicemia causing significant economic losses in the swine industry.
Sophie Peterhans, Peter Kuhnert, Kuhnert, Peter, Stephan, Roger, Giovanni Ghielmetti, Scherrer, Simone, Simone Scherrer, Sarah Schmitt, Roger Stephan, Schmitt, Sarah, Peterhans, Sophie, Fenja Rademacher, Ghielmetti, Giovanni, Rademacher, Fenja   +13 more
core   +3 more sources

Exploration of clinical breakpoint of Danofloxacin for Glaesserella parasuis in plasma and in PELF [PDF]

Antibiotics, 2021
Abstract Background To establish the clinical breakpoint (CBP) of danofloxacin to G. parasuis , three cutoff values, including epidemiological cutoff value (ECV), pharmacodynamic cutoff value (CO PD )
Zihui Xu, Anxiong Huang, Xun Luo, Peng Zhang, Lingli Huang, Xu Wang, Kun Mi, Shiwei Fang, Xiao Huang, Jun Li, Zonghui Yuan, Haihong Hao   +11 more
openaire   +4 more sources

The Glaesserella parasuis phosphoglucomutase is partially required for lipooligosaccharide synthesis [PDF]

Veterinary Research, 2020
AbstractLipooligosaccharides (LOSs) are virulence determinants of Glaesserella parasuis, a pathogen of the respiratory tract of pigs. We previously reported that disruption of the galU or galE gene in G. parasuis results in increased sensitivity to porcine serum, indicating that the galactose catabolism pathway is required for polysaccharide formation ...
Saixiang Feng, Aihua Chen, Xiaobing Wang, Zhichao Pan, Siqi Xu, Huiwen Yu, Bin Zhang, Ming Liao   +7 more
openaire   +4 more sources

The Molecular Mechanism by Which miR-129a-3p Targets the TLR4/NF-κB Signaling Pathway to Regulate Inflammatory Damage in 3D4/21 Cells Infected with Glaesserella parasuis [PDF]

Animals
Glaesserella parasuis (G. parasuis) is the primary pathogen responsible for Glässer’s disease and poses a significant threat to the global pig industry. MicroRNAs are a class of short, endogenous, single-stranded noncoding RNAs that play crucial roles in
Zhongbo Guo, Yuanyuan Zhou, Na Li, Aobo Shen, Yongchao Jia, Ronglan Yin, Junjie Yang, Jing Yuan, Ronghuan Yin   +8 more
doaj   +2 more sources

Importance of strain selection in the generation of heterologous immunity to Glaesserella (Haemophilus) parasuis [PDF]

Veterinary Immunology and Immunopathology, 2021
Glaesserella (Haemophilus) parasuis is a part of the microbiota of healthy pigs and also causes the systemic condition called Glässer's disease. G. parasuis is categorized by it capsular polysaccharide into 15 serovars. Because of the serovar and strain specific immunity generated by whole cell vaccines and the rapid onset of disease, G.
Samantha J. Hau, Kirsten C. Eberle, Susan L. Brockmeier   +2 more
openaire   +2 more sources

Transcriptome Analysis of miRNA and mRNA in Porcine Skeletal Muscle following Glaesserella parasuis Challenge [PDF]

Genes (Basel)
Glaesserella parasuis (G. parasuis) causes systemic infection in pigs, but its effects on skeletal muscle and underlying mechanisms are poorly understood. We investigated G.
Xiaoyu Zhang, Xinqi Zeng, Huanhuan Zhou, Hongbo Chen, Ke Xu, Xuexue Chen, Xiangwei Deng   +6 more
core   +2 more sources