Results 111 to 120 of about 2,719 (158)

Baicalin Attenuated PANX-1/P2X7 Axis, P2Y6, and NLRP3/Caspase-1 Signaling Pathways in Peritonitis Induced by Glaesserella parasuis

Microbiology Research, 2023
Glaesserella parasuis (G. parasuis) can cause peritonitis in piglets. However, the pathogenesis of peritonitis remains unclear. Baicalin has been shown to possess anti-inflammatory and anti-oxidant functions.
Shulin Fu, Xinyue Tian, Jingyang Li, Yuzhen Yuan, Xiaoyi Li, Mingxing Ren, Ling Guo, Chun Ye, Bingbing Zong, Yu Liu, Qirong Lu, Yinsheng Qiu   +11 more
doaj   +1 more source

Use of Subtherapeutic Tylvalosin Against Mycoplasma hyopneumoniae: Implications For Respiratory Microbiome Dysbiosis and Swine Lung Health

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Enzootic pneumonia (EP) caused by Mycoplasma hyopneumoniae (M. hyopneumoniae) has a significant impact on swine production. Subtherapeutic exposures of tylvalosin in swine, often due to inconsistent dosing in feed or water, promote antimicrobial resistance.
Leonardo Teófilo Toledo, Richard Costa Polveiro, Caio Augustus Diamantino, Gustavo Manoel Rigueira Simão, Carlos Eduardo Real Pereira, Eduardo de Freitas Costa, Maria Aparecida Scatamburlo Moreira, Fernanda Simone Marks, Orhan Sahin   +8 more
wiley   +1 more source

Characterization and protective activity of monoclonal antibodies directed against Fe (3+) ABC transporter substrate-binding protein of Glaesserella parasuis

Veterinary Research, 2021
Glässer’s disease is caused by the agent Glaesserella parasuis and is difficult to prevent and control. Candidate screening for subunit vaccines contributes to the prevention of this disease. Therefore, in this study, the inactivated G.
Kexin Zhu, Dong Yu, Jiahui An, Yufeng Li
doaj   +1 more source

Comprehensive lung microbial gene and genome catalogs assist the mechanism survey of Mesomycoplasma hyopneumoniae strains causing pig lung lesions

iMeta, Volume 3, Issue 6, December 2024.
In this study, we utilized 744 metagenomic sequencing data from lower respiratory tract microbial samples of 675 well‐phenotyped pigs across five cohorts. From these, we constructed a microbial gene catalog containing 10,031,593 nonredundant genes and 356 metagenome‐assembled genomes (MAGs), which were further clustered into 256 species‐level genome ...
Jingquan Li, Fei Huang, Yunyan Zhou, Tao Huang, Xinkai Tong, Mingpeng Zhang, Jiaqi Chen, Zhou Zhang, Huipeng Du, Zifeng Liu, Meng Zhou, Yiwen Xiahou, Huashui Ai, Congying Chen, Lusheng Huang   +14 more
wiley   +1 more source

A field evaluation of a new porcine circovirus type 2d and Mycoplasma hyopneumoniae bivalent vaccine in herds suffering from subclinical PCV2d infection and enzootic pneumonia

Veterinary Medicine and Science, Volume 10, Issue 5, September 2024.
This study investigates the efficacy of a new bivalent vaccine targeting porcine circovirus type 2d (PCV2d) and Mycoplasma hyopneumoniae across three pig farms with histories of subclinical PCV2 infections and enzootic pneumonia. Vaccinated pigs showed higher average daily weight gains, an increased production of neutralizing anti‐PCV2 antibodies and a
Sehyeong Ham, Jeongmin Suh, Chonghan Kim, Byoung‐Joo Seo, Gyeong‐Seo Park, Chanhee Chae   +5 more
wiley   +1 more source

Baicalin attenuates PD-1/PD-L1 axis-induced immunosuppression in piglets challenged with Glaesserella parasuis by inhibiting the PI3K/Akt/mTOR and RAS/MEK/ERK signalling pathways

Veterinary Research
Infection of piglets with Glaesserella parasuis ( G. parasuis ) induces host immunosuppression. However, the mechanism underlying the immunosuppression of piglets remains unclear.
S. Fu, Jingyang Li, Jiarui You, Siyu Liu, Qiaoli Dong, Yunjian Fu, Ronghui Luo, Yamin Sun, Xinyue Tian, Wei Liu, Jingyi Zhang, Yu Ding, Yitian Zhang, Wutao Wang, Ling Guo, Yinsheng Qiu   +15 more
semanticscholar   +1 more source

Field efficacy of a novel porcine reproductive and respiratory syndrome modified‐live virus vaccine with an emphasis on growth performance

Veterinary Medicine and Science, Volume 10, Issue 4, July 2024.
This field evaluation tested a new PRRSV‐2 modified live virus vaccine's efficacy on three pig farms affected by PRRSV‐2. Forty 18‐day‐old pigs per farm were randomly assigned to vaccinated or unvaccinated groups. Vaccinated pigs had higher body weight, better daily weight gain and showed immune responses with PRRS antibodies and PRRSV‐2‐specific ...
Sehyeong Ham, Hyunjoon Lee, Jeongmin Suh, Chonghan Kim, Woo Ju Kwon, Gyeong‐Seo Park, Chanhee Chae   +6 more
wiley   +1 more source

Biofilm formation in Streptococcus suis: in vitro impact of serovars and assessment of coinfections with other porcine respiratory disease complex bacterial pathogens [PDF]

[EN] Streptococcus suis is a worldwide pathogen that impacts the swine industry, causing severe clinical signs, including meningitis and arthritis, in postweaning piglets. A key virulence mechanism of S.
Delgado García, Mario, González Fernández, Alba, Gutiérrez Martín, César Bernardo, Martínez Martínez, Sonia, Mencía Ares, Óscar, Miguélez Pérez, Rubén, Rilo, Máximo Petrocchi   +6 more
core   +1 more source

The establishment and application of a one‐step multiplex real‐time polymerase chain reaction assay for the detection of Streptococcus suis, Streptococcus suis serotype 2, and Glaesserella parasuis

Animal Research and One Health, Volume 2, Issue 1, Page 59-70, February 2024.
This article aims to establish a multiplex real‐time polymerase chain reaction (PCR) assay for the simultaneous detection of Streptococcus suis (SS), Streptococcus suis serotype 2 (SS2), and Glaesserella parasuis (GPS). In this study, three pairs of primers and three probes were designed based on the specific sequences of SS (gdh), SS2 (cps2j), and GPS
Lingxiang Xin, Haojie Wang, Yunhao Hu, Yan Liu, Wensheng Yao, Xiuli Wang, Jian Li, Yuanjie Liu, Rendong Tong, Qi Wang, Youlong Lu, Liangquan Zhu   +11 more
wiley   +1 more source

Investigating the relationship between antimicrobial susceptibility and serovar of Glaesserella parasuis

, 2023
Abstract Background Glaesserella parasuis (G. parasuis) is the causative agent of Glässer’s disease and causes severe economic losses in the swine industry. Vaccination and antimicrobial therapy are crucial to Glässer’s disease prevention and control, and antimicrobial resistance (AMR) is an important issue.
Wei-Hao Lin, Cheng-Yao Yang, Chuen-Fu Lin, Chao-Nan Lin, Ming-Tang Chiou   +4 more
openaire   +1 more source