Results 141 to 150 of about 2,719 (158)
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Neuraminidase and pH responsive nano-drug against resistant Glaesserella parasuis.
International Journal of Biological MacromoleculesGlaesserella parasuis (GPS) infection leads to significant economic losses in livestock, with antibiotic resistance exacerbating the issue. The lengthy development cycle of new drugs further complicates timely intervention. Neuraminidase, a virulence factor of GPS, plays a critical role in infection progression.
Zhixin Lei +4 more
semanticscholar +3 more sources
Multi-epitope vaccines Xlc and Ddc against Glaesserella parasuis infection in mice.
Veterinary MicrobiologyGlaesserella parasuis (synonym Haemophilus parasuis) is the pathogenic agent of Glässer's disease and causes huge economic losses in the world's swine industry. Glaesserella parasuis (G. parasuis) can be divided into 15 serotypes, and the cross-protection effect of existing vaccines is not satisfactory.
Lu Dai +9 more
semanticscholar +3 more sources
Development of a Luminex microbead-based serotyping assay for Glaesserella parasuis
Journal of Microbiological Methods, 2021Glaesserella parasuis consists of 15 serovars with some of them highly virulent and some of them avirulent. As killed vaccines do not provide crossprotection across serovars, serotyping is of importance. Serotyping, previously done by gel diffusion, is now done by multiplex PCR followed by electrophoresis.
Sarah, Yee +5 more
openaire +2 more sources
Preventive Veterinary Medicine, 2020
Haemophilus parasuis, a gram-negative bacterium as an early commensal colonizer in the upper respiratory tract of weaning pigs (Sus scrofa), is one of the most important bacterial pathogens affecting pig populations. It is the causative agent of Glässer's disease, causing systemic infection and polyserositis, meningitis, and arthritis. H.
Hong-Bo, Ni +4 more
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Haemophilus parasuis, a gram-negative bacterium as an early commensal colonizer in the upper respiratory tract of weaning pigs (Sus scrofa), is one of the most important bacterial pathogens affecting pig populations. It is the causative agent of Glässer's disease, causing systemic infection and polyserositis, meningitis, and arthritis. H.
Hong-Bo, Ni +4 more
openaire +2 more sources
Pathotyping and molecular serotyping of clinical isolates of Glaesserella parasuis in Taiwan
Brazilian Journal of MicrobiologyGlaesserella parasuis is a bacterial pathogen that causes severe economic losses in the swine industry worldwide. In this study, 262 G. parasuis isolates from pigs with Glässer's disease obtained between 2015 and 2022 in Taiwan were serotyped, pathotyped, and analyzed for virulence genes. The most prevalent serovars were 5 (29%), 4 (27.9%), 12 (12.2%),
Wei-Hao Lin +6 more
semanticscholar +3 more sources
PK/PD modelling of enrofloxacin againstGlaesserella parasuisinfection in pigs
Journal of Veterinary Pharmacology and Therapeutics, 2022AbstractA pharmacokinetic/pharmacodynamic (PK/PD) model was developed to optimize the dosing regimen of enrofloxacin (EN) againstGlaesserella parasuisin pigs. EN (2.5 mg/kg) was administered intramuscularly to eight healthy pigs and eight pigs that were experimentally infected withG. parasuisSW124.
Bo Yang +7 more
openaire +2 more sources
Virulence assessment of four Glaesserella parasuis strains isolated in Liaoning province of China
Research in Veterinary Science, 2023Glaesserella parasuis (G. parasuis) is a part of the normal upper respiratory microbiota of healthy swine. In many studies, the serovars 1, 4, 5, and 12 of G. parasuis are considered to be highly virulent and its serovars 3, 6, 7, 9, and 11 are considered to be non-virulent. Until now, researchers have found that non-virulent strains of G.
Ping, Yan +11 more
openaire +2 more sources
ACS Infectious Diseases, 2021
Pathogens utilize various mechanisms to escape host immunological surveillance, break down different tissue barriers, and cause infection. Sialylation is an important surface modification of bacterial outer membrane components, especially the lipooligosaccharide of Gram-negative bacteria.
Huan Wang +10 more
openaire +2 more sources
Pathogens utilize various mechanisms to escape host immunological surveillance, break down different tissue barriers, and cause infection. Sialylation is an important surface modification of bacterial outer membrane components, especially the lipooligosaccharide of Gram-negative bacteria.
Huan Wang +10 more
openaire +2 more sources
Microbial Drug Resistance, 2023
Glässer's disease is caused by Glaesserella parasuis , a common bacterium in the upper respiratory tract of pigs. Antibiotics are widely used to control this disease. A G. parasuis isolate with amoxicillin (AMX) resistance was identified in our previous
Jiahui, An, Chao, Zhang, Yufeng, Li
openaire +2 more sources
Glässer's disease is caused by Glaesserella parasuis , a common bacterium in the upper respiratory tract of pigs. Antibiotics are widely used to control this disease. A G. parasuis isolate with amoxicillin (AMX) resistance was identified in our previous
Jiahui, An, Chao, Zhang, Yufeng, Li
openaire +2 more sources
Veterinary Microbiology
Glaesserella parasuis (GPS) is the causative agent of Glässer's disease, leading to significant economic losses in the global swine industry. During post-mortem inspection, the main observation in pigs affected by Glässer's disease is the presence of serofibrinous or fibrinopurulent exudate on the mucosal surface.
Bin, Ma +9 more
openaire +2 more sources
Glaesserella parasuis (GPS) is the causative agent of Glässer's disease, leading to significant economic losses in the global swine industry. During post-mortem inspection, the main observation in pigs affected by Glässer's disease is the presence of serofibrinous or fibrinopurulent exudate on the mucosal surface.
Bin, Ma +9 more
openaire +2 more sources