Results 71 to 80 of about 14,264 (186)

Glucagon-like peptide analogues for type 2 diabetes mellitus : systematic review and meta-analysis [PDF]

open access: yes, 2010
Background Glucagon-like peptide (GLP-1) analogues are a new class of drugs used in the treatment of type 2 diabetes. They are given by injection, and regulate glucose levels by stimulating glucose-dependent insulin secretion and biosynthesis ...
Deepson S Shyangdan   +18 more
core   +2 more sources

rDNA insulin glargine U300 – a critical appraisal

open access: yes, 2016
Fei Wang,1 Stefanie Zassman,1 Philip A Goldberg2 1Department of Pharmacy Practice, School of Pharmacy, University of Connecticut, Storrs, CT, USA; 2Department of Internal Medicine, Section of Endocrinology, Yale University School of Medicine, New Haven ...
Goldberg PA, Wang F, Zassman S
core  

Recombinant glargine insulin production process using Escherichia coli

open access: yes, 2016
Glargine insulin is a long-acting insulin analog that helps blood glucose maintenance in patients with diabetes. We constructed the pPT-GI vector to express prepeptide glargine insulin when transformed into Escherichia coli JM109. The transformed E. coli
C K Kim   +7 more
core   +1 more source

South Asian Consensus Guideline: Use of insulin in diabetes during Ramadan

open access: yesIndian Journal of Endocrinology and Metabolism, 2012
A person with diabetes mellitus (DM) has every right to perform the ritual of fasting during Ramadan. In daily practice we come across both type 1 and type 2 DM who wish to fast.
Md Faruque Pathan   +9 more
doaj   +1 more source

Forum for injection techniques, India: The first Indian recommendations for best practice in insulin injection technique

open access: yesIndian Journal of Endocrinology and Metabolism, 2012
Advances in the treatment of diabetes have led to an increase in the number of injectable therapies, such as human insulin, insulin analogues, and glucagon-like peptide-1 analogues.
Sanjay Kalra   +13 more
doaj   +1 more source

Long-term insulin glargine therapy in type 2 diabetes mellitus: a focus on cardiovascular outcomes

open access: yes, 2015
Joshua J Joseph, Thomas W Donner Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA Abstract: Cardiovascular disease is the leading cause of mortality in type 2 ...
Joseph JJ, Donner TW
core  

Effective use of saline-diluted subcutaneous glargine in very low birth weight babies with neonatal hyperglycemia

open access: yesJournal of Family Medicine and Primary Care
This case series documents two very low birth weight neonates who presented with spontaneous hyperglycemia even after discontinuation of steroids in a critical care setting.
Akhila Bhandarkar   +3 more
doaj   +1 more source

Insulin glargine: The first clinically useful extended-action insulin analogue

open access: yes, 2001
Insulin glargine is a new extended-action insulin analogue, created by recombinant DNA modification of human insulin. Extension of the C-terminal of the B-chain with two arginine residues and the substitution of glycine for asparagine at position A-21 ...
Home PD; Ashwell SG
core   +5 more sources

Insulin glargine in the treatment of type 1 and type 2 diabetes 59

open access: yes, 2006
Anthony H BarnettBirmingham Heartlands Hospital, Birmingham, West Midlands, England, UKAbstract: Insulin glargine is an analogue of human insulin that is modified to provide a consistent level of plasma insulin over a long duration.
Barnett, Anthony, Anthony H Barnett
core  

Study of the aggregation of insulin glargine by light scattering

open access: yes, 2006
Insulin glargine (Lantus1, Aventis Pharma, Deutschland, GmbH) is a new long-acting human insulin analog. Structural modification of the insulin molecule at two sites alters its pH, causing insulin glargine to precipitate in the neutral environment of ...
R Coppolino, S Coppolino, V Villari
core   +1 more source

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