Results 21 to 30 of about 21,105,669 (168)

Advanced Role of Neutrophils in Common Respiratory Diseases [PDF]

open access: yesJournal of Immunology Research, Volume 2017, Issue 1, 2017., 2017
Respiratory diseases, always being a threat towards the health of people all over the world, are most tightly associated with immune system. Neutrophils serve as an important component of immune defense barrier linking innate and adaptive immunity.
Fang Wang   +6 more
core   +3 more sources

Glaucocalyxin B Attenuates Ovarian Cancer Cell Growth and Cisplatin Resistance In Vitro via Activating Oxidative Stress. [PDF]

open access: yesOxid Med Cell Longev, 2022
Ovarian cancer is one of the fatal gynecological cancers around the world. Cisplatin is the first‐line chemotherapy drug for the clinical treatment of ovarian cancer. However, many patients with ovarian cancer are still suffering from resistance to cisplatin.
Zhang T   +11 more
europepmc   +2 more sources

Glaucocalyxin a protect liver function via inhibiting platelet over-activation during sepsis.

open access: yesPhytomedicine, 2022
Rabdosia japonica (Burm. f.) var. glaucocalyx (Maxim.) is a perennial herb, and is traditionally used as folk medicine for treating inflammatory diseases and cancer. Gaucocalyxin A (GLA) is an ent‑kaurane diterpenoid that is isolated from the aerial parts of R. japonica (Burm. f.) var. glaucocalyx (Maxim.). In a recent study, we found that GLA protects
Jiang Jiang   +7 more
semanticscholar   +3 more sources

Design, Synthesis and Biological Evaluation of Novel Thiazole-Fused Glaucocalyxin A Derivatives [PDF]

open access: yesChinese Journal of Organic Chemistry, 2021
Tao Zhang   +9 more
semanticscholar   +2 more sources

Effect of glaucocalyxin B on the protein expressions of PTEN, Beclin1 and LC3 in a mouse model of transplanted cervical cancer, and its significance [PDF]

open access: yes, 2022
Purpose: To determine the effect of glaucocalyxin B (GLB) on the protein expressions of PTEN, Beclin1 and LC3 in a mouse model of transplanted cervical cancer, and its significance.Methods: A mouse model of transplanted cervical cancer was established in
Han, Zhengyang   +3 more
core   +2 more sources

Anthocyanin attenuates oxygen-glucose deprivation/reperfusion-induced apoptosis of PC12 cells via inactivation of ASK1/JNK/p38 signaling pathway [PDF]

open access: yes, 2021
Purpose: To investigate whether the cytoprotective effect of anthocyanin (Anc) on oxygen-glucose deprivation/reperfusion (OGD/R)-induced cell injury is related to apoptosis signal-regulating kinase 1 (ASK1)/c-Jun N-terminal kinase (JNK)/p38 signaling ...
Guan, Bin   +6 more
core   +2 more sources

Melatonin Promotes BMSCs Osteoblastic Differentiation and Relieves Inflammation by Suppressing the NF‐κB Pathways

open access: yesStem Cells International, Volume 2023, Issue 1, 2023., 2023
Bone mesenchymal stem cells (BMSCs) play an important role in maintaining the dynamic balance of bone metabolism. Recent studies have reported that a decrease in the osteogenic function of MSCs is strongly associated with osteoporosis. Melatonin is a neuroendocrine hormone produced in the pineal gland and is essential in the physiological regulation ...
Yiqiang Hu   +12 more
wiley   +1 more source

Regulatory Mechanism of M1/M2 Macrophage Polarization in the Development of Autoimmune Diseases

open access: yesMediators of Inflammation, Volume 2023, Issue 1, 2023., 2023
Macrophages are innate immune cells in the organism and can be found in almost tissues and organs. They are highly plastic and heterogeneous cells and can participate in the immune response, thereby playing a crucial role in maintaining the immune homeostasis of the body.
Yuan Peng   +8 more
wiley   +1 more source

Computational profiling and prognostic modeling based on lysosome-related genes in colorectal cancer [PDF]

open access: yes, 2023
Background: Despite significant advances over the past decade, patients diagnosed with advanced colorectal cancer (CRC) continue to face unfavorable prognoses.
Jingbang Yang   +8 more
core   +1 more source

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