Results 21 to 30 of about 12,298 (216)

Gliadin Nanoparticles Induce Immune Tolerance to Gliadin in Mouse Models of Celiac Disease [PDF]

Gastroenterology, 2020
Celiac disease could be treated, and potentially cured, by restoring T-cell tolerance to gliadin. We investigated the safety and efficacy of negatively charged 500-nm poly(lactide-co-glycolide) nanoparticles encapsulating gliadin protein (TIMP-GLIA) in 3 mouse models of celiac disease. Uptake of these nanoparticles by antigen-presenting cells was shown
Tobias L. Freitag, Joseph R. Podojil, Ryan M. Pearson, Frank J. Fokta, Cecilia Sahl, Marcel Messing, Leif C. Andersson, Katarzyna Leskinen, Päivi Saavalainen, Lisa I. Hoover, Kelly Huang, Deborah Phippard, Sanaz Maleki, Nicholas J.C. King, Lonnie D. Shea, Stephen D. Miller, Seppo K. Meri, Daniel R. Getts   +17 more
openaire   +4 more sources

Different levels of humoral immunoreactivity to different wheat cultivars gliadin are present in patients with celiac disease and in patients with multiple myeloma

BMC Immunology, 2009
Background Immunity to food antigens (gliadin, cow's milk proteins) is in the centre of the attention of modern medicine focused on the prevention of diseases, prevention which is based on the use of appropriate restriction diet.
Bonaci-Nikolic Branka, Besu Irina, Radic Jelena, Ninkovic Aleksandra, Stankovic Ivan, Jelic Svetislav, Krstic Radmilo, Dodig Dejan, Konic-Ristic Aleksandra, Jojic Njegica, Djordjevic Milica, Popovic Dragan, Juranic Zorica   +12 more
doaj   +1 more source

ON THE ANALYTICAL ESTIMATION OF GLIADIN. [PDF]

Journal of the American Chemical Society, 1908
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openaire   +2 more sources

Trehalose Modulates Autophagy Process to Counteract Gliadin Cytotoxicity in an In Vitro Celiac Disease Model

Cells, 2019
Celiac disease (CD) is a chronic systemic autoimmune disorder that is triggered by the ingestion of gliadin peptides, the alcohol-soluble fraction of wheat gluten.
Federico Manai, Alberto Azzalin, Martina Morandi, Veronica Riccardi, Lisa Zanoletti, Marco Dei Giudici, Fabio Gabriele, Carolina Martinelli, Mauro Bozzola, Sergio Comincini   +9 more
doaj   +1 more source

Optimization of large-scale purification of omega gliadins and other wheat gliadins

Journal of Cereal Science, 2022
Among wheat storage proteins, omega-gliadins display a singular amino acid sequence only composed by re-petitive sequences. They have been described as a major wheat allergen and also contain T-cell epitopesimplicated in coeliac disease. To study the structural and biophysical properties of omega-gliadins and othergliadins (e.g., gluten network ...
Solé-Jamault, Véronique, Davy, Joëlle, Cochereau, Rémy, Boire, Adeline, Larré, Colette, Denery-Papini, Sandra   +5 more
openaire   +3 more sources

Involvement of gliadin, a component of wheat gluten, in increased intestinal permeability leading to non-steroidal anti-inflammatory drug-induced small-intestinal damage.

PLoS ONE, 2019
Gliadin, a component of wheat gluten known to be an important factor in the etiology of celiac disease, is related to several other diseases through its enhancing effect on intestinal paracellular permeability. We investigated the significance of gliadin
Sunao Shimada, Tetsuya Tanigawa, Toshio Watanabe, Akinobu Nakata, Naoki Sugimura, Shigehiro Itani, Akira Higashimori, Yuji Nadatani, Koji Otani, Koichi Taira, Shuhei Hosomi, Yasuaki Nagami, Fumio Tanaka, Noriko Kamata, Hirokazu Yamagami, Masatsugu Shiba, Yasuhiro Fujiwara   +16 more
doaj   +1 more source

Identification of gliadin-binding peptides by phage display

BMC Biotechnology, 2011
Background Coeliac disease (CD) is a common and complex disorder of the small intestine caused by intolerance to wheat gluten and related edible cereals like barley and rye.
Östman Sofia, Hoffmann Karolina, Chen Tingsu, Sandberg Ann-Sofie, Olsson Olof   +4 more
doaj   +1 more source

Allergenicity of Deamidated and/or Peptide-Bond-Hydrolyzed Wheat Gliadin by Transdermal Administration

Foods, 2020
Hydrochloric acid (HCl)-treated wheat protein (HWP) is widely used in various products, including foods, cosmetics and shampoos. Recently, immediate hypersensitivity towards facial soap containing HWP has been reported.
Ryosuke Abe, Narumi Matsukaze, Hayato Kobayashi, Yusuke Yamaguchi, Harumi Uto-Kondo, Hitoshi Kumagai, Hitomi Kumagai   +6 more
doaj   +1 more source

EVALUATION OF GRAIN QUALITY PROPERTIES OF SOME IRAQI AND ICARDA SELECTED DURUM WHEAT CULTIVARS [PDF]

Mesopotamia Journal of Agriculture, 2005
Four samples of Iraqi durum wheat cultivars and six selected varieties of ICARDA were involved in this study, for their grain quality tests and flour rheological properties comparison. Their gliadin electrophoresis was also conducted.
Ahmed Salih Khalaf
doaj   +1 more source

Markers of Celiac Disease and Gluten Sensitivity in Children with Autism. [PDF]

PLoS ONE, 2013
Gastrointestinal symptoms are a common feature in children with autism, drawing attention to a potential association with celiac disease or gluten sensitivity. However, studies to date regarding the immune response to gluten in autism and its association
Nga M Lau, Peter H R Green, Annette K Taylor, Dan Hellberg, Mary Ajamian, Caroline Z Tan, Barry E Kosofsky, Joseph J Higgins, Anjali M Rajadhyaksha, Armin Alaedini   +9 more
doaj   +1 more source