Effects of Gliadin on Autoimmune Responses of Central Nervous System of C57BL/6 Mice
Iranian Journal of Allergy, Asthma and Immunology, 2021 Gluten sensitivity contributes to various degrees of neurological manifestations and neurodegenerative immunological changes. We investigated the experimental features of anti-gliadin immune responses in the central nervous system (CNS) of mice.
Parisa Esmaeili +6 more
doaj +1 more source
The Dietary Intervention of Transgenic Low-Gliadin Wheat Bread in Patients with Non-Celiac Gluten Sensitivity (NCGS) Showed No Differences with Gluten Free Diet (GFD) but Provides Better Gut Microbiota Profile [PDF]
, 2018 The study evaluated the symptoms, acceptance, and digestibility of bread made from transgenic low-gliadin wheat, in comparison with gluten free bread, in Non-coeliac gluten sensitivity (NCGS) patients, considering clinical/sensory parameters and gut ...
Comino Montilla, Isabel María +10 more
core +1 more source
Novel mechanisms of gliadin immunotoxicity? [PDF]
Gut, 2010 These results open the way for alternative therapies for Coeliac Disease based on the use of antioxidants, TGt inhibitors (and PPARg modulators), or the re-induction of tolerance. Competing interests None.
Arranz Sanz, Eduardo +1 more
openaire +4 more sources
Chemosensors, 2022 User-friendly devices for detecting low gliadin content in commercial foods are of extreme importance for people with gluten diseases. With this concern, the present work proposes a rapid and sensitive optical nanostructured microarrays platform for the ...
Giuliocesare Casari Bariani +4 more
doaj +1 more source
Passage of Gliadin into Human Breast Milk [PDF]
Acta Paediatrica, 1986 ABSTRACT. Samples of breast milk were taken from 53 women following the ingestion of 20 g of gluten. The samples were analysed for the presence of gliadin by a double‐antibody sandwich enzyme immunoassay. Gliadin (5–95 ng/ml) was detected in 54/80 samples collected at various stages of lactation.
TRONCONE, RICCARDO +5 more
openaire +6 more sources
Celiac Immunogenic Potential of α-Gliadin Epitope Variants from Triticum and Aegilops Species [PDF]
, 2019 The high global demand of wheat and its subsequent consumption arise from the physicochemical properties of bread dough and its contribution to the protein intake in the human diet.
Barro Losada, Francisco +8 more
core +1 more source
Detection of secretory IgA antibodies against gliadin and human tissue transglutaminase in stool to screen for coeliac disease in children: validation study [PDF]
, 2006 Objective To evaluate two commercial stool tests for detection of secretory IgA antibodies against gliadin and human tissue transglutaminase for diagnosis of coeliac disease in children with symptoms.Setting Tertiary care children's hospital.Participants
Diehl, Veronika +4 more
core +2 more sources
Pharmaceutically modified subtilisins withstand acidic conditions and effectively degrade gluten in vivo [PDF]
, 2019 Detoxification of gluten immunogenic epitopes is a promising strategy for the treatment of celiac disease. Our previous studies have shown that these epitopes can be degraded in vitro by subtilisin enzymes derived from Rothia mucilaginosa, a natural ...
Darwish, Ghassan +4 more
core +1 more source
Gliadin Nanoparticles Induce Immune Tolerance to Gliadin in Mouse Models of Celiac Disease [PDF]
Gastroenterology, 2020 Celiac disease could be treated, and potentially cured, by restoring T-cell tolerance to gliadin. We investigated the safety and efficacy of negatively charged 500-nm poly(lactide-co-glycolide) nanoparticles encapsulating gliadin protein (TIMP-GLIA) in 3 mouse models of celiac disease. Uptake of these nanoparticles by antigen-presenting cells was shown
Tobias L. Freitag +17 more
openaire +4 more sources
BMC Immunology, 2009 Background Immunity to food antigens (gliadin, cow's milk proteins) is in the centre of the attention of modern medicine focused on the prevention of diseases, prevention which is based on the use of appropriate restriction diet.
Bonaci-Nikolic Branka +12 more
doaj +1 more source