Results 1 to 10 of about 6,552 (233)

Gliadin Nanoparticles Induce Immune Tolerance to Gliadin in Mouse Models of Celiac Disease [PDF]

Gastroenterology, 2020
Celiac disease could be treated, and potentially cured, by restoring T-cell tolerance to gliadin. We investigated the safety and efficacy of negatively charged 500-nm poly(lactide-co-glycolide) nanoparticles encapsulating gliadin protein (TIMP-GLIA) in 3 mouse models of celiac disease. Uptake of these nanoparticles by antigen-presenting cells was shown
Tobias L. Freitag, Joseph R. Podojil, Ryan M. Pearson, Frank J. Fokta, Cecilia Sahl, Marcel Messing, Leif C. Andersson, Katarzyna Leskinen, Päivi Saavalainen, Lisa I. Hoover, Kelly Huang, Deborah Phippard, Sanaz Maleki, Nicholas J.C. King, Lonnie D. Shea, Stephen D. Miller, Seppo K. Meri, Daniel R. Getts   +17 more
openaire   +3 more sources

Analysis of expressed sequence tags from a single wheat cultivar facilitates interpretation of tandem mass spectrometry data and discrimination of gamma gliadin proteins that may play different functional roles in flour

BMC Plant Biology, 2010
Background The gamma gliadins are a complex group of proteins that together with other gluten proteins determine the functional properties of wheat flour.
Altenbach Susan B, Vensel William H, DuPont Frances M   +2 more
doaj   +1 more source

Quantification of gliadin levels to the picogram level by flow cytometry [PDF]

, 2005
Celiac disease is a widely prevalent enteropathy caused by intolerance to gliadin, one of the gluten proteins. We developed two methods for the analysis of gliadin levels. Both methods use flow cytometry and rat antibodies against a 16-residue peptide of
CAPPARELLI R, IANNELLI D., LONGOBARDO, LUIGI, VENTIMIGLIA L   +3 more
core   +1 more source

Microcellular foams made from gliadin [PDF]

Colloid and Polymer Science, 2014
We have generated closed-cell microcellular foams from gliadin, an abundantly available wheat storage protein. The extraction procedure of gliadin from wheat gluten, which involves only the natural solvents water and ethanol, respectively, is described with emphasis on the precipitation step of gliadin which results in a fine dispersion of mostly ...
Quester, S., Dahesh, Mohsen, Strey, R.
openaire   +4 more sources

Genetic diversity for gliadin patterns of durum wheat landraces in the Northwest of Iran and Azerbaijan

Pesquisa Agropecuária Brasileira, 2010
The objective of this study was to identify gliadin band patterns and the extent of genetic diversity in durum wheat genotypes from Northwestern Iran and the Republic of Azerbaijan.
Mohammad Zaefizadeh, Shahzad Jamaati-e-Somarin, Javid Ojaghi, Seyed Mehdi Seyedi, Roghayyeh Zabihi-e-Mahmoodabad, Mehran Ochi   +5 more
doaj   +1 more source

Celiac Immunogenic Potential of α-Gliadin Epitope Variants from Triticum and Aegilops Species [PDF]

, 2019
The high global demand of wheat and its subsequent consumption arise from the physicochemical properties of bread dough and its contribution to the protein intake in the human diet.
Barro Losada, Francisco, Comino Montilla, Isabel María, López Casado, Miguel Ángel, Moreno Amador, María de Lourdes, Ozuna Serafini, Carmen Victoria, Ruiz Carnicer, Ángela, Segura Montero, Verónica, Sousa Martín, Carolina, Torres López, María Isabel   +8 more
core   +1 more source

A PCR-based method for discriminating between high molecular weight glutenin subunits Bx7 and Bx7* in Triticum aestivum L [PDF]

, 2012
The correct assignment of high molecular weight glutenin subunit variants is a key task in wheat breeding. However, the traditional analysis by protein electrophoresis is sometimes difficult and not very precise.
Carrillo Becerril, Jose Maria, Espí Plaza, Araceli, Giraldo Carbajo, Patricia, Rodriguez de Quijano Urquiaga, Marta   +3 more
core   +2 more sources

Proteomic Profiling and Epitope Analysis of the Complex α-, γ-, and ω-Gliadin Families in a Commercial Bread Wheat

Frontiers in Plant Science, 2018
Wheat gliadins are a complex group of proteins that contribute to the functional properties of wheat flour doughs and contain epitopes that are relevant for celiac disease (CD) and wheat-dependent exercise-induced anaphylaxis (WDEIA).
Kyoungwon Cho, Hye-Rang Beom, You-Ran Jang, Susan B. Altenbach, William H. Vensel, Annamaria Simon-Buss, Sun-Hyung Lim, Min G. Kim, Jong-Yeol Lee   +8 more
doaj   +1 more source

Evaluation of novel serological markers and autoantibodies in dogs with inflammatory bowel disease

Journal of Veterinary Internal Medicine, 2020
Background The use of serological markers to diagnose inflammatory bowel disease (IBD) in humans is well‐established. Because of the frequency of IBD in dogs and resources required for its diagnosis with current methods, new approaches are desired ...
Juan J. Estruch, Derren Barken, Nicole Bennett, Donald K. Krawiec, Gregory K. Ogilvie, Barbara E. Powers, Benjamin J. Polansky, Michael T. Sueda   +7 more
doaj   +1 more source

Retracted: Utility of the combined use of 3 serologic markers in the diagnosis and monitoring of chronic enteropathies in dogs

Journal of Veterinary Internal Medicine, 2021
Background Dogs with chronic enteropathies (CE) displayed elevated IgA seropositivity against specific markers that can be used to develop a novel test.
Juan Estruch, Jacqueline Johnson, Sarah Ford, Sean Yoshimoto, Tracy Mills, Philip Bergman   +5 more
doaj   +1 more source