Antisense suppression of glial fibrillary acidic protein as a treatment for Alexander disease
Tracy L. Hagemann +7 more
semanticscholar +1 more source
CDC42‐Effector Proteins Regulate Higher Order Structure of Septins Required for CNS Myelin Integrity
CDC42‐effector proteins 1/2 are present in CNS myelin. They facilitate the higher order structure of myelin septin filaments. Their loss impairs septin‐dependent scaffolding of myelin. Myelin outfoldings do not cause secondary neuropathology per se. ABSTRACT The regular structure of CNS myelin requires specialized structural proteins, including septin ...
Sophie Hümmert +14 more
wiley +1 more source
Plasma Glial Fibrillary Acidic Protein Correlates With Brain Metal Burden in Wilson's Disease. [PDF]
Fan SP +12 more
europepmc +1 more source
ABSTRACT One of the great triumphs of mass spectrometry‐based peptide and protein characterization is the characterization of their modifications as most modifications have a characteristic mass shift. What happens when the modification does not change the mass of the peptide?
Samuel Okyem, Jonathan V. Sweedler
wiley +1 more source
Moderating effects of plasma glial fibrillary acidic protein along the Alzheimer's disease continuum. [PDF]
Lee SY +35 more
europepmc +1 more source
x‐ray phase‐contrast tomography enabled three‐dimensional, label‐free visualization and quantification of protein aggregates in neurodegenerative diseases with isotropic submicrometer resolution. The study revealed distinct electron density patterns in Lewy bodies, Hirano bodies, granulovacuolar degeneration, and amyloid plaques, highlighting their ...
Jonas Franz +9 more
wiley +1 more source
Glial Fibrillary Acidic Protein Astrocytopathy Based on a Two-Center Chinese Cohort Study. [PDF]
Wu T +13 more
europepmc +1 more source
Plasma Glial Fibrillary Acidic Protein in the Differential Diagnosis of Intracerebral Hemorrhage
A. Katsanos +13 more
semanticscholar +1 more source
Calponin‐3 is associated with epilepsy through the regulation of astrocyte activity
Increased calponin‐3 expression correlates with astrocyte activation in epileptic mice, modulating adenosine metabolism regulators ADK and ENT1. Calponin‐3 overexpression increased susceptibility to epileptic seizures, while its downregulation reduces spontaneous recurrent seizures, identifying it as a potential therapeutic target for epilepsy ...
Lu Chen +12 more
wiley +1 more source
Genetic and epigenetic analysis of plasma glial fibrillary acidic protein (GFAP) levels in PTSD. [PDF]
Miller MW +5 more
europepmc +1 more source

