Results 251 to 260 of about 70,938 (290)
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The endless story of the glial fibrillary acidic protein
Journal of Cell Science, 1994ABSTRACT All intermediate filament proteins consist of an α-helical rod domain flanked by non-helical N-terminal head and C-terminal tail domains. The roles of the non-helical domains of various intermediate filament proteins in the assembly and co-assembly of higher-order filamentous structures have been studied by many groups but with ...
W J, Chen, R K, Liem
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Glial fibrillary acidic protein and Alzheimer's disease
Neurochemical Research, 1985A major protein associated with Alzheimer's disease (AD) was detected by an electrophoretic study of temporal cortex obtained at autopsy from patients affected with AD, non-AD dementia, and normal controls matched for age and sex. A markedly increased amount of a 50,000 dalton molecular weight protein, which has been identified as glial fibrillary ...
S S, Panter +4 more
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Measurement of Glial Fibrillary Acidic Protein
Current Protocols in Toxicology, 2002AbstractToxicant‐induced injury of the adult or developing central nervous system results in hypertrophy of astrocytes at the site of injury. The hallmark of this response is enhanced expression of the major intermediate filament protein of astrocytes, glial fibrillary acid protein (GFAP).
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Ammonia Induced Decrease in Glial Fibrillary Acidic Protein in Cultured Astrocytes
Journal of Neuropathology and Experimental Neurology, 1990 Previous studies of human hepatic encephalopathy (HE) have shown decreased levels of glial fibrillary acidic protein (GFAP) in Alzheimer type II astrocytes.
Joseph T Neary +2 more
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Localization of the glial fibrillary acidic protein in astrocytes by immunofluorescence
Brain Research, 1972Abstract The glial fibrillary acidic (GFA) protein, a brain specific protein extracted from severely gliosed human tissue, is not species specific; cross-reaction occurs between anti-human GFA protein antibodies and brain extracts of rabbit, guinea pig, rat and dog.
A, Bignami +3 more
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Assembly, disassembly, and exchange of glial fibrillary acidic protein
Glia, 1991AbstractThe kinetics and dynamics of glial fibrillary acidic protein (GFAP) assembly was explored by a fluorescence energy transfer assay method. Purified GFAP was stoichiometrically labeled at a single cysteine residue with fluorescein‐maleimide.
Y, Nakamura +5 more
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Dynamics of bovine glial fibrillary acidic protein phosphorylation
Neuroscience Letters, 1996Recently, the dynamic features of the intermediate filaments (IF) have been revealed. The effect of phosphorylation on the dynamics of bovine glial fibrillary acidic protein (GFAP), the astroglial IF, was studied in vitro with fluorescently labeled GFAP.
Y, Nakamura, M, Takeda, T, Nishimura
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Glial fibrillary acidic protein in the fish optic nerve
Glia, 1991AbstractThe intermediate filament glial fibrillary acidic protein (GFAP) is the predominant cytoskeletal protein of mature glial cells in the mammalian nervous system. The nervous systems of lower vertebrates, such as fish, have been examined for the presence of GFAP and several investigators have shown that goldfish (Carassius auratus) brain contains ...
E, Blaugrund +3 more
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[The glial fibrillary acidic protein].
Presse medicale (Paris, France : 1983), 1991Since it was discovered, twenty years ago, the glial fibrillary acidic protein has been the subject of more than 500 publications. The huge interest it has raised up is probably due partly to its abundance in the central nervous system and also, above all, to its cellular specificity which makes it the universally recognized marker of astrocytes.
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Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy
Neurology India, 2023Yuxin, Deng, Mingguo, Xie, Lichuan, Zeng
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