Results 131 to 140 of about 82,505 (300)

Case Reports: Three cases of autoimmune glial fibrillary acidic protein astrocytosis in disguise

Frontiers in Immunology
Autoimmune glial fibrillary acidic protein astrocytosis (GFAP-A), a novel inflammatory autoimmune disorder of the central nervous system, manifests with insidious onset and demonstrates protean clinical manifestations, which frequently leads to ...
Wen Zhao, Luyao Gong, Junbin Wang, Zhiguang Chen, Zhiguang Chen, Zhe Li, Zhe Li, Qiaozhen Su, Qiaozhen Su, Youbi Shen, Youbi Shen, Chunye Zheng, Chunye Zheng   +12 more
doaj   +1 more source

Differential detection of impact site versus rotational site injury by magnetic resonance imaging and microglial morphology in an unrestrained mild closed head injury model. [PDF]

, 2016
Seventy-five percent of all traumatic brain injuries are mild and do not cause readily visible abnormalities on routine medical imaging making it difficult to predict which individuals will develop unwanted clinical sequelae. Microglia are brain-resident
Carson, Monica J, Donovan, Virgina, Grinberg, Yelena Y, Hernandez, Alfredo, Obenaus, Andre   +4 more
core  

Supratentorial hydrocephalus with an anti-glial fibrillary acidic protein (GFAP) antibody-positive status: A case report. [PDF]

CNS Neurosci Ther, 2022
Tang L, Zhang L, Zhang M, Zeng Y, Li Y.
europepmc   +1 more source

Perampanel Blocks Transsynaptic α‐Synuclein Propagation and Neurodegeneration in a Mouse Model of Lewy Body Disease

Movement Disorders, EarlyView.
Abstract Background Transsynaptic α‐synuclein propagation plays a crucial role in the progression of Lewy body disease. We previously demonstrated that an α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor antagonist, perampanel, blocks neuronal uptake of α‐synuclein preformed fibrils (PFFs) in an activity‐dependent manner.
Jun Ueda, Norihito Uemura, Jiarui Chang, Tetsuya Hirato, Tomoyuki Ishimoto, Miki Oono, Shuichi Matsuzawa, Riki Matsumoto, Hodaka Yamakado, Ryosuke Takahashi   +9 more
wiley   +1 more source

Peripheral nervous system involvement accompanies central nervous system involvement in anti-glial fibrillary acidic protein (GFAP) antibody-related disease. [PDF]

J Neurol, 2023
Theuriet J, Cluse F, Gravier-Dumonceau A, Picard G, Closs S, Rogemond V, Timestit N, Bouhour F, Petiot P, Davy V, Chanson E, Arzalluz-Luque J, Marignier R, Honnorat J, Pegat A.   +14 more
europepmc   +1 more source

Unilateral mastication‐induced memory deficits linked to disrupted hippocampal cholesterol metabolism in rats

VIEW, EarlyView.
Unilateral mastication, a common oral habit, induces cognitive decline in rats by disrupting hippocampal cholesterol metabolism. It triggers astrocyte hyperplasia, enhances cholesterol synthesis, impairs transport/degradation, and reduces 24‐hydroxycholesterol (24‐OHC), ultimately damaging synaptic function.
Xiaoting Zhai, Yifan Hu, Rongchen Xu, Xinyu Xu, Bowen Ma, Dongzong Huang, Hongchen Liu, Hongbo Li, Yuan Hu, Hua Jiang   +9 more
wiley   +1 more source

Mode Characterization and Sensitivity Evaluation of a Surface Acoustic Wave (SAW) Resonator Biosensor: Application to the Glial-Fibrillary-Acidic-Protein (GFAP) Biomarker Detection. [PDF]

Micromachines (Basel), 2023
Passeri AM, Lunardelli F, Cavariani D, Cecchini M, Agostini M.   +4 more
europepmc   +1 more source

14‐3‐3σ up‐regulation in the temporal cortex associates with tau pathology and reactive astroglia in Lewy body disorders

Brain Pathology, EarlyView.
14‐3‐3 protein homeostasis is disrupted in Lewy body pathology, showing a diminution of six isotypes and overexpression of stratifin. The latter was associated with stratifin colocalization with tau pathology and reactive astrocytes. Platelets, as a peripheral biomarker source, mirrored inversely cortical 14‐3‐3 gene expression patterns in dementia ...
Laura Marsal‐García, Jorge Mena, Carol‐Ann Lao, David Adamuz, Laura Arnaldo, Cristina Carrato, Alex Menendez, Daniela Samaniego, Dolores Vilas, Lourdes Ispierto, Anna Planas, Ramiro Alvarez, Pau Pastor, Katrin Beyer   +13 more
wiley   +1 more source

Maturation of astrocytes in the rat hippocampus : potential behavioral implications [PDF]

Diversos trabajos han mostrado que la astroglía juega un papel relevante en la fisiología del sistema nervioso central. Sin embargo, aún existen pocos estudios que se hayan centrado en el análisis de la población astroglial durante el desarrollo ...
Arias Pérez, Jorge Luis, Cimadevilla Redondo, José Manuel, Conejo Jiménez, Nélida María, González Pardo, Héctor, Vallejo Seco, Guillermo   +4 more
core  

Ultrasensitive Determination of Glial-Fibrillary-Acidic-Protein (GFAP) in Human Serum-Matrix with a Label-Free Impedimetric Immunosensor. [PDF]

Biosensors (Basel), 2022
Ozcelikay G, Mollarasouli F, Unal MA, Gucuyener K, Ozkan SA.   +4 more
europepmc   +1 more source