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Changes in Glial Fibrillary Acidic Protein (GFAP) Immonureactivity Reflect Neuronal States
Neurochemical Research, 2008The astroglial marker, glial fibrillary acidic protein (GFAP) was investigated by immunohistochemistry in various brain areas in order to see its fluctuations in various functional states. Different neuronal states were either experimentally induced or studied under physiological conditions.
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Veterinary Record, 2007
To establish clinical markers for canine necrotising meningoencephalitis ( nme ) and to elucidate its pathogenesis, glial fibrillary acidic protein ( gfap ) and anti‐ gfap autoantibodies were measured in the ...
Y, Toda +5 more
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To establish clinical markers for canine necrotising meningoencephalitis ( nme ) and to elucidate its pathogenesis, glial fibrillary acidic protein ( gfap ) and anti‐ gfap autoantibodies were measured in the ...
Y, Toda +5 more
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Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1994
S100 protein, a subfamily of Ca(2+)-binding proteins of the EF-hand type, was recently shown to bind to and to inhibit the polymerization of the glial fibrillary acidic protein (GFAP), the intermediate filament component of astroglial cells, in the presence of micromolar levels of Ca2+ (J. Biol. Chem. 268, 12669-12674).
BIANCHI, Roberta +4 more
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S100 protein, a subfamily of Ca(2+)-binding proteins of the EF-hand type, was recently shown to bind to and to inhibit the polymerization of the glial fibrillary acidic protein (GFAP), the intermediate filament component of astroglial cells, in the presence of micromolar levels of Ca2+ (J. Biol. Chem. 268, 12669-12674).
BIANCHI, Roberta +4 more
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The Journal of Gene Medicine, 2007
AbstractGlial fibrillary acidic protein (GFAP) is an intermediate filament protein abundantly expressed in malignant gliomas. We have constructed a novel oncolytic adenovirus, Ad5‐gfa2(B)3‐E1, for treatment of these tumors. In this construct, the E1 region is under control of the tissue‐specific GFAP promoter (gfa2) with three additional copies of the ...
Horst, Maarten +7 more
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AbstractGlial fibrillary acidic protein (GFAP) is an intermediate filament protein abundantly expressed in malignant gliomas. We have constructed a novel oncolytic adenovirus, Ad5‐gfa2(B)3‐E1, for treatment of these tumors. In this construct, the E1 region is under control of the tissue‐specific GFAP promoter (gfa2) with three additional copies of the ...
Horst, Maarten +7 more
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Journal of Neuroimmunology, 1985
The glial fibrillary acidic protein (GFA protein or GFAP) is the major protein constituent of glial intermediate filaments in differentiated fibrous and protoplasmic astrocytes of the central nervous system. Proteins having similar molecular weights, isoelectric points, and immunoreactivity with GFAP have been found in cells of neural crest and ...
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The glial fibrillary acidic protein (GFA protein or GFAP) is the major protein constituent of glial intermediate filaments in differentiated fibrous and protoplasmic astrocytes of the central nervous system. Proteins having similar molecular weights, isoelectric points, and immunoreactivity with GFAP have been found in cells of neural crest and ...
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Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease
Nature Genetics, 2001Alexander disease is a rare disorder of the central nervous system of unknown etiology. Infants with Alexander disease develop a leukoencephalopathy with macrocephaly, seizures and psychomotor retardation, leading to death usually within the first decade; patients with juvenile or adult forms typically experience ataxia, bulbar signs and spasticity ...
M, Brenner +5 more
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Infection, 1996
Glial fibrillary acidic protein (GFAp), the main protein constituent of the intermediate filaments of astrocytes, was analysed in the cerebrospinal fluid (CSF) of 20 patients with Lyme neuroborreliosis as a marker of the astroglial reaction. The mean GFAp level before antibiotic treatment in the study group was significantly elevated (592 pg/ml +/- 596
L, Dotevall, L E, Rosengren, L, Hagberg
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Glial fibrillary acidic protein (GFAp), the main protein constituent of the intermediate filaments of astrocytes, was analysed in the cerebrospinal fluid (CSF) of 20 patients with Lyme neuroborreliosis as a marker of the astroglial reaction. The mean GFAp level before antibiotic treatment in the study group was significantly elevated (592 pg/ml +/- 596
L, Dotevall, L E, Rosengren, L, Hagberg
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Glial fibrillary acidic protein (GFAP) immunoreactivity in enteric ganglia of the chick embryo
Brain Research, 1998We examined by immunohistochemistry the expression of glial fibrillary acidic protein (GFAP) in enteric ganglia of the chick embryo, using a polyclonal antibody. The morphology of enteric ganglion cells was examined by electron microscopy. Faint GFAP immunoreactivity was detected in ganglion cells and cell processes from around day 7 in ovo.
C, Balaskas, G, Gabella
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Expression of glial fibrillary acidic protein (GFAP) in goldfish optic nerve following injury
Glia, 1990AbstractBy using an antibody to goldfish glial fibrillary acidic protein (GFAP), the reaction of goldfish optic nerve to injury has been studied by immunoblotting and immunohistochemical methods. Goldfish optic nerve, which normally lacks GFAP immunoreactivity (Nona et al.: Glia, 2:189–200, 1989), expresses GFAP following injury. This immunoreactivity,
C A, Stafford +3 more
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The contemporary management of cancers of the sinonasal tract in adults
Ca-A Cancer Journal for Clinicians, 2023Rajat Thawani
exaly