Results 121 to 130 of about 319,103 (346)

Intraventricular glioblastoma

open access: yesPan African Medical Journal, 2014
Glioblastoma represents 15%-20% of all intracranial tumors and approximately 50 % of gliomas in adults. Although capable of arising anywhere in the central nervous system, these tumors mainly present as a frontotemporal lesion (63%) of the cerebral cortex.
El Mostarchid B, Mandour C
openaire   +4 more sources

Advances in local therapy for glioblastoma — taking the fight to the tumour

open access: yesNature Reviews Neurology, 2022
T. S. van Solinge   +3 more
semanticscholar   +1 more source

Current Challenges and Opportunities in Treating Glioblastoma

open access: yesPharmacological Reviews, 2018
Glioblastoma multiforme (GBM), the most common and aggressive primary brain tumor, has a high mortality rate despite extensive efforts to develop new treatments.
Andrea G Shergalis   +4 more
semanticscholar   +1 more source

Advanced Multipurpose Spectroscopic Nanobio‐Device for Concurrent Lab‐on‐a‐Chip Label‐Free Separation and Detection of Extracellular Vesicles as Key‐Biomarkers for Point‐of‐Care Cardiovascular Disease Diagnostics

open access: yesAdvanced Healthcare Materials, EarlyView.
AIMSPec‐LoC is a novel lab‐on‐a‐chip platform integrating size‐based extracellular vesicle (EVs) separation with label‐free Raman spectroscopy and AI‐powered classification via SKiNET. This high‐throughput, portable system enables real‐time, multiplexed molecular fingerprinting of EVs from biofluids, offering transformative potential for early, non ...
Emma Buchan   +3 more
wiley   +1 more source

Aging on Chip: Harnessing the Potential of Microfluidic Technologies in Aging and Rejuvenation Research

open access: yesAdvanced Healthcare Materials, EarlyView.
This review highlights recent advances in microfluidic technologies for modeling human aging and age‐related diseases. It explores how organ‐on‐chip platforms improve physiological relevance, enable rejuvenation strategies, facilitate drug screening, detect senescent cells, and identify biomarkers.
Limor Zwi‐Dantsis   +5 more
wiley   +1 more source

Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization

open access: yesNature Neuroscience, 2021
Ana Rita Pombo Antunes   +27 more
semanticscholar   +1 more source

Multifunctional Biomedical Devices with Closed‐Loop Systems for Precision Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores two major types of closed‐loop therapeutic systems: self‐sustained and externally triggered. It highlights recent advances in stimuli‐responsive materials, integrated bioelectronics, and data‐driven control strategies, offering insight into emerging strategies for personalized, responsive drug delivery.
Yixuan Leng, Rujie Sun
wiley   +1 more source

Tumor Microenvironment‐responsive Nanocatalyst for Targeted Chemodynamic Cancer Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
An Tumor microenvironment‐responsive nanocatalyst system composed of PLGA‐encapsulated Ca–Fe peroxide and polyarginine enables sustainable Fenton reaction in tumors. Low levels of H2O2 (50–100 µm) initiate the nanoparticle degradation, while polyarginine‐derived nitric oxide accelerates Fe3+ reduction, leading to self‐amplifying •OH generation for ...
Jun Ma, Jingjing Qiu, Shiren Wang
wiley   +1 more source

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