Results 111 to 120 of about 261,478 (313)

Real-world management and survival outcomes of patients with newly diagnosed gliomas from a single institution in China: A retrospective cohort study

Glioma, 2019
Background and Aim: Guidelines recommend adjuvant treatment for patients with high-grade gliomas and low-grade gliomas with high risk of progression. In clinical practice, however, treatments may not conform to these suggested guidelines.
Depei Li, Yinsheng Chen, Chengcheng Guo, Xiangheng Zhang, Ke Sai, Chao Ke, Ji Zhang, Xiaobing Jiang, Zhenghe Chen, Fuhua Lin, Qunying Yang, Jian Wang, Yonggao Mu, Zhongping Chen   +13 more
doaj   +1 more source

Gliomas [PDF]

BioMed Research International, 2014
Lombardi, Giuseppe, Della Puppa, Alessandro, Di Stefano, Anna Luisa, Pace, Andrea, Rudà, Roberta, Tabouret, Emeline, Zagonel, Vittorina   +6 more
openaire   +2 more sources

Strategies of eradicating glioma cells : a multi-scale mathematical model with miR-451-AMPK-mTOR control [PDF]

, 2015
The cellular dispersion and therapeutic control of glioblastoma, the most aggressive type of primary brain cancer, depends critically on the migration patterns after surgery and intracellular responses of the individual cancer cells in response to ...
Gibin Powathil, Trucu Dumitru, Kang Hyunji, Kim Hyeongi, Chaplain Mark, Lawler Sean, Mark Chaplain, Gibin Powathil (687047), Powathil, Gibin, Hyeongi Kim, Trucu, Dumitru, Kim, Hyeongi, Dumitru Trucu, Sean Lawler (191146), Kim, Yangjin, Hyunji Kang, Hyeongi Kim (687050), Yangjin Kim, Lawler, Sean, Kim Yangjin, Sean Lawler, Kang, Hyunji, Hyunji Kang (687048), Trucu, Dumitru; id_orcid, Dumitru Trucu (687049), Mark Chaplain (249544), Powathil Gibin, Chaplain, Mark, Yangjin Kim (191134)   +28 more
core   +1 more source

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Advanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake, Md Shahriar A. Hossain, Chia‐Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud   +5 more
wiley   +1 more source

The delta-like ligand 4-notch signaling inhibits tumor angiogenesis but promotes tumor growth in primary glioblastoma: An immunohistochemical study

Glioma, 2018
Background: Delta-like ligand 4 (DLL4) is a key Notch ligand implicated in tumor angiogenesis. However, previous studies have shown that the DLL4-Notch signaling inhibits tumor angiogenesis but promotes tumor progression in primary glioblastoma.
Yao Chen, Zhi-Xiong Lin, Jin-Tao Chen, Ming-Cheng Zheng   +3 more
doaj   +1 more source

Psychiatric symptoms in glioma patients: from diagnosis to management [PDF]

, 2015
Florien W Boele,1 Alasdair G Rooney,2 Robin Grant,2 Martin Klein1 1Department of Medical Psychology, VU University Medical Center, Amsterdam, the Netherlands; 2Department of Clinical Neurosciences, Western General Hospital, Edinburgh, UK Abstract ...
Grant, R, Grant R, Rooney, AG, Grant, R., Rooney, A.G., Klein M, Boele FW, Rooney AG, Klein, M, Boele, FW, Boele, F.W., Klein, M.   +11 more
core   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source

Nur77 knock-down suppresses glioma by regulating CXCR4

, 2020
Introduction The aim of this study is to explain the effects and mechanisms of Nur77 in glioma development. Material and methods Nur77 protein and gene expression were measured by immunohistochemistry and real-time quantitative polymerase chain reaction
Jing Zheng, Zheng, Jing, Ni, Hongbin, Jing Wang, Yu, Cheng, Wei Zhou, Zhou, Wei, Wang, Jing, Cheng Yu, Dai, Yuxiang, Yuxiang Dai, Yu Ding, Zhang, Liexiang, Hongbin Ni, Liexiang Zhang, Ding, Yu   +15 more
core   +1 more source

Redirecting Monocyte Differentiation With Engineered Extracellular Vesicles for Glioma Immunotherapy. [PDF]

Adv Sci (Weinh)
A dual‐targeting engineered extracellular vesicles (M1‐CS‐EVs) platform is developed to redirect monocytes differentiation into anti‐tumor macrophages for glioma immunotherapy. This nanoplatform combines CAR‐mediated tumor recognition with localized CD47 blockade, leading to synergistic immune activation and potent suppression of tumor progression in ...
Pan Y, Liu X, Meng QF, Cao L, Li R, Xu Y, Zhang J, Zhao C, Rao L, Yu C.   +9 more
europepmc   +2 more sources

Blood–Brain Barrier Regulation: Evolving From Classic Strategies to Electrochemical Ion and Reactive Oxygen Species Control

Advanced Healthcare Materials, EarlyView.
Conventional therapies suffer from poor blood–brain barrier (BBB) penetration and disordered ion/reactive oxygen species (ROS) homeostasis, hindering precise neurological treatment. Electrochemical strategies achieve accurate spatiotemporal regulation of neural homeostasis.
Xiaokang Hu, Caiyu Liu, Meijun Pang, Zhiyuan Shi, Dong Ming, Xiuyun Liu   +5 more
wiley   +1 more source