Results 111 to 120 of about 382,034 (365)

Sex differences in genomics, immune microenvironment and immunotherapy response in adult grade 4 gliomas

open access: yesClinical and Translational Discovery
Purpose Sex differences in the prevalence of gliomas have been reported; however, whether there are sex differences in the development and immunotherapy of gliomas remains poorly understood.
Feng Tang   +4 more
doaj   +1 more source

cIMPACT-NOW Update 3: Recommended diagnostic criteria for “Diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV”

open access: yesActa Neuropathologica, 2018
Working Committee 1 concluded that histologic grade II and III IDH-wildtype diffuse astrocytic gliomas that contain high-level EGFR amplification, the combination of whole chromosome 7 gain and whole chromosome 10 loss (+7/−10), or TERT promoter ...
D. Brat   +11 more
semanticscholar   +1 more source

IN4MER Biomaterial Ink: A Phosphorescent Biosensing Biomaterial Ink for Multiple Analytes (Glucose, Lactate, Oxygen) Measurements and Temperature Sensing Applications

open access: yesAdvanced Functional Materials, EarlyView.
Multianalyte, real‐time monitoring of bioprinted scaffolds remains challenging. Phosphorescence‐lifetime–based, optically responsive microparticles are embedded in diverse printable hydrogels (κ‐carrageenan, GelMA, PEGDA) to form biomaterial inks that report oxygen, glucose, lactate, and temperature.
Waqas Saleem   +11 more
wiley   +1 more source

The Glioma Stem Cell Model in the Era of Single-Cell Genomics.

open access: yesCancer Cell, 2020
Glioma stem cells (GSCs) are thought to underlie glioma initiation, evolution, and resistance to existing therapies. Although functional evidence for GSCs is abundant, tumor heterogeneity and intrinsic limitations in GSC assays have represented barriers ...
M. Suvà, I. Tirosh
semanticscholar   +1 more source

Glioma-associated mutations identified in cell lines used in this study.

open access: yes, 2018
Glioma-associated mutations identified in cell lines used in this study.
Mindy K. Graham (5759450)   +11 more
core   +1 more source

Inhibition of HIV-1 replication by small interfering RNAs directed against Glioma Pathogenesis Related Protein (GliPR) expression [PDF]

open access: yes, 2010
Background: Previously, we showed that glioma pathogenesis related protein (GliPR) is induced in CEM T cells upon HIV-1 infection in vitro. To examine whether GliPR plays a role as HIV dependency factor (HDF), we tested the effect of GliPR suppression by
Scheuring Urban J   +17 more
core   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Neutrophil extracellular traps mediate the crosstalk between glioma progression and the tumor microenvironment via the HMGB1/RAGE/IL-8 axis

open access: yesCancer Biology and Medicine, 2020
Objective: Neutrophil extracellular traps (NETs) produced by tumor-infiltrating neutrophils (TINs) are associated with poor prognosis in patients with several types of cancer.
Caijun Zha   +10 more
semanticscholar   +1 more source

Glioma-associated region co-localizes with a selective sweep.

open access: yes, 2016
A view of the most associated region for glioma (A) and inspection of minor allele frequencies shows that low minor allele frequencies (indicative of selection) in breeds related to an ancestral Bulldog (B) co-localize with the associated region.
Kartika Jayashankar (546862)   +16 more
core   +1 more source

Engineering of Glioblastoma‐Derived Biomimetic Vesicles and Their Structural and Molecular Features

open access: yesAdvanced Healthcare Materials, EarlyView.
ABSTRACT Biomimetic nanosystems and vesicles have arisen as a novel approach to design vesicular transport systems with diverse therapeutic potential. The ‘biomimetic’ strategy involves the integration of cell membrane components into lipid bilayers, conferring them with biological properties originating from the cell of origin. Until now, most studies
Noelia Hernández‐Lobato   +6 more
wiley   +1 more source

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