Results 121 to 130 of about 382,034 (365)
BMC CancerBackground Gliomas are the deadliest malignant tumors of the adult central nervous system. We previously discovered that beta2-microglobulin (B2M) is abnormally upregulated in glioma tissues and that it exerts a range of oncogenic effects.
Zhen-Yuan Liu +6 more
doaj +1 more source
Molecular and clinical characterization of TIM-3 in glioma through 1,024 samples
OncoImmunology, 2017 Background: Researches on immunotherapy of glioma has been increasing exponentially in recent years. However, autoimmune-like side effects of current immune checkpoint blockade hindered the clinical application of immunotherapy in glioma.
Guanzhang Li +15 more
doaj +1 more source
Adult Glioma Incidence and Survival by Race or Ethnicity in the United States From 2000 to 2014
JAMA Oncology, 2018 Importance Glioma is the most commonly occurring malignant brain tumor in the United States, and its incidence varies by age, sex, and race or ethnicity. Survival after brain tumor diagnosis has been shown to vary by these factors.
Q. Ostrom +4 more
semanticscholar +1 more source
Ivosidenib in Isocitrate Dehydrogenase 1–Mutated Advanced Glioma
Journal of Clinical Oncology, 2020 PURPOSE Diffuse gliomas are malignant brain tumors that include lower-grade gliomas (LGGs) and glioblastomas. Transformation of low-grade glioma into a higher tumor grade is typically associated with contrast enhancement on magnetic resonance imaging ...
I. Mellinghoff +20 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang +17 more
wiley +1 more source
MicroRNA-based chemoresistance in glioblastoma
Glioma, 2019 Glioblastoma (GBM) is the most common malignant tumor of the central nervous system in adults. GBM is characterized by violent invasion and poor prognosis.
Zhenghui Ma +3 more
doaj +1 more source
Leptin Induces Migration and Invasion of Glioma Cells through Mmp-13 Production
, 2010 Leptin, the product of the obese gene, plays an important role in the regulation of body weight by coordinating metabolism, feeding behavior, energy balance, and neuroendocrine responses.
葉威蘭;盧大宇;李銘仁;符文美 +1 more
core +1 more source
Microengineered Gradient Hydrogels for Mechanobiology
Advanced Healthcare Materials, EarlyView.Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong +4 more
wiley +1 more source
Exosomal noncoding RNAs in Glioma: biological functions and potential clinical applications
Molecular Cancer, 2020 Gliomas are complex and heterogeneous brain tumors with poor prognosis. Glioma cells can communicate with their surroundings to create a tumor-permissive microenvironment.
Jian Cheng +3 more
semanticscholar +1 more source