Results 151 to 160 of about 424,107 (362)
OBSERVATIONS ON A CASE OF CEREBRAL CORTICO-MEDULLARY GLIOMA [PDF]
, 1883 David Ferrier
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Advanced Science, EarlyView.FA directly binds to residue H378 of DDX6 and promotes its interaction with HSC70, leading to CMA degradation of DDX6, thereby impairing GSK‐3β/β‐catenin signaling, inhibiting ABC transporter proteins, and enhancing chemosensitivity. Abstract ABC transporter protein‐mediated drug efflux is a significant contributor to induced resistance in breast ...
Xiaxia Fan +5 more
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INTEGRATIVE ANALYSIS OF OMICS DATA IN ADULT GLIOMA AND OTHER TCGA CANCERS TO GUIDE PRECISION MEDICINE [PDF]
, 2017 Transcriptomic profiling and gene expression signatures have been widely applied as effective approaches for enhancing the molecular classification, diagnosis, prognosis or prediction of therapeutic response towards personalized therapy for cancer ...
hu, Xin, hu, xin
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Advanced Science, EarlyView.This study identifies ZDHHC12 as a critical mediator of PA‐induced HCC progression. Mechanistically, PA upregulates ZDHHC12 expression through SMARCA4 activation, leading to HDAC8 palmitoylation at Cys244 which blocks HSC70‐mediated lysosomal degradation of HDAC8, thereby promoting HCC development. These findings provide novel mechanistic insights into
Xin Jin +7 more
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Glioma Treated by Intra-Ocular Insertion of Radium [PDF]
, 1930 R. Foster Moore
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Homologous self-organising scale-invariant properties characterise long range species spread and cancer invasion [PDF]
, 2007 The invariance of some system properties over a range of temporal and/or spatial scales is an attribute of many processes in nature1, often characterised by power law functions and fractal geometry2.
Bo Hu +4 more
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From Bench to Bedside: Emerging Paradigms in CAR‐T Cell Therapy for Solid Malignancies
Advanced Science, EarlyView.This review discusses emerging paradigms in CAR‐T cell therapy for solid tumors, emphasizing strategies to overcome therapeutic barriers through synthetic biology, immune engineering, and combinatorial approaches. It highlights advancements in logic gating, modulation of the immune microenvironment, and innovative cell designs, providing valuable ...
Yang Chen +7 more
wiley +1 more source
Advanced Science, EarlyView.This study identifies that RBM10 represses the transcriptional activity of RORB in liquid condensates, resulting in down‐regulation of NR1D1 and RIOK3 that further activates NF‐κB activity to facilitate lysosomal biogenesis and aggressive features of NB cells.
Yanhua Guo +9 more
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Advanced Science, EarlyView.This figure is a candidate for the cover image. It shows a whole‐mount fluorescent image of lymphatic vessels (red) in the heart of an adult Cdh5‐Dre; Prox1‐RSR‐CreER; Rosa26‐tdT mouse. Image courtesy of Ximeng Han. Abstract Cell fate determination is a fundamental process in multicellular development.
Hui Chen +3 more
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