Anakinra treatment for refractory cerebral autoinflammatory responses
Abstract Refractory cerebral autoinflammatory–autoimmune diseases are often associated with dysregulated innate immunity and are targeted by anakinra, an interleukin‐1 receptor antagonist. We analyzed the therapeutic effect of anakinra in refractory cerebral autoinflammatory response (CAIR) at a single institution from January 2017 to May 2021.
Yoonhyuk Jang +5 more
wiley +1 more source
Gliomatosis Cerebri: Current Understanding and Controversies
Gliomatosis cerebri (GC) is a rare, extensively infiltrating glioma involving multiple contiguous lobes of the brain. This lethal disease affects all age groups, and the majority of patients have a poor outcome despite aggressive treatment.
Surabhi Ranjan, Katherine E. Warren
doaj +1 more source
Prospective single-arm study of 72 Gy hyperfractionated radiation therapy and combination chemotherapy for anaplastic astrocytomas [PDF]
Background Despite intensive multimodal treatment, outcome of patients with malignant glioma remains poor, and a standard dose of radiotherapy for anaplastic astrocytoma has not been defined.
Takuma Nomiya +24 more
core +1 more source
A rare case of gliomatosis cerebri lurking beneath the shadows of a stroke mimic
Gliomatosis cerebri (GC) is a diffuse infiltrative neoplastic glial process with a devastating prognosis. Considering its rarity, unpredictable clinical manifestations, and lack of characteristic radiographic features, GC is a difficult diagnosis that is
Apoorv Prasad, MD +4 more
doaj +1 more source
The 2016 World Health Organization Classification of tumours of the Central Nervous System: what the paediatric neuroradiologist needs to know [PDF]
The recently published 2016 World Health Organization (WHO) classification of tumours of the Central Nervous System (CNS) introduces a number of significant changes from the previous edition.
Carney, O +4 more
core +1 more source
Gliomatosis cerebri mimicking diffuse demyelinating disease: Case Report
Gliomatosis Cerebri (GC) is a rareand rapidly progressive pattern of growth of diffusely infiltrating gliomas with limited treatment options. Imaging findings are usually nonspecific and can mimic other neurologic disorders, including demyelination ...
Erli Mingomataj, MD +3 more
doaj +1 more source
Clinical characteristics and radiological features of glioblastoma, IDH-wildtype, grade 4 with histologically lower-grade gliomas [PDF]
The 2021 World Health Organization (WHO) classification of central nervous system tumors applied molecular criteria and further integrated histological and molecular diagnosis of gliomas.
Aoki, Kosuke +5 more
core +1 more source
Bevacizumab and temozolomide in secondary gliomatosis from gemistocytic astrocytoma: a case report
Gliomatosis cerebri is a rare diffuse glioma with a growth pattern consisting of exceptionally extensive infiltration of the CNS with involvement of at least three lobes. It may appear de novo (primary gliomatosis) or result from the spreading of a focal
Elisa Trevisan +3 more
doaj +1 more source
Gliomatosis cerebri with blindness: A case report with literature review
Cerebral gliomatosis (GC) is a rare diffuse infiltrative growth pattern of glioma with nonspecific clinical manifestations like visual impairment that may involve bilateral temporal lobes.
Amirreza Jahanshahi, MD +8 more
doaj +1 more source
Severe and prolonged myelosuppression during concomitant temozolomide and radiotherapy treatment in a patient with glioblastoma multiforme [PDF]
Aims: We describe the case of a patient with glioblastoma (GBM) who developed severe and prolonged myelosuppression during concomitant daily temozolomide (TMZ) and radiotherapy (RT) treatment.
ALOE SPIRITI, Maria Antonietta +12 more
core +1 more source

