Results 101 to 110 of about 58,440 (301)
Abstract Objective Rasmussen's encephalitis (RE) is a rare and progressive, immune‐mediated epileptic encephalopathy characterized by drug‐resistant seizures and neurological decline. While hemispheric disconnection (HD) is the gold standard treatment for effective seizure control, this procedure carries significant risk of permanent neurological ...
Krish Nair +11 more
wiley +1 more source
Abstract Objective Surgical decision‐making in temporal lobe epilepsy (TLE) faces a critical challenge in determining whether the hippocampus can be safely spared during anterior temporal resection, particularly when surgery involves the language‐dominant hemisphere.
Guhan Seshadri NP +6 more
wiley +1 more source
Ultrafast oscillations in the human brain and their functional significance
Abstract Objective The upper frequency limit of human brain activity remains unknown. Using ultrahigh sampling rate (≥20 kHz) intracranial microelectroencephalography, this study aimed to systematically explore and quantitatively characterize brain field oscillations beyond the established high‐frequency oscillation range (>2 kHz), and to determine ...
Milan Brázdil +13 more
wiley +1 more source
Ionizing radiation induces astrocyte gliosis through microglia activation
The aim of this study was to investigate the role of microglia in radiation-induced astrocyte gliosis. We found that a single dose of 15 Gy radiation to a whole rat brain increased immunostaining of glial fibrillary acidic protein in astrocytes 6 h later,
오억수
core +2 more sources
Abstract Objective Meditation has widely recognized psychological and neuromodulatory benefits, yet its effects on epileptiform activity remain unclear. This study examined whether novice meditation modulates interictal epileptiform discharges (IEDs) in patients with drug‐resistant epilepsy using intracranial electroencephalography (iEEG).
Shweta Soni +5 more
wiley +1 more source
The dynamic functional connectivity peak index: Detection of interictal epileptic activity with fMRI
Abstract Objective Epileptogenic zone (EZ) localization is crucial for surgical treatment of patients with medication‐resistant epilepsy. Although simultaneous electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) can detect interictal discharges for EZ localization, clinical adoption is limited by the need for specialized ...
Lucas E. Sainburg +9 more
wiley +1 more source
Reactive gliosis in the injured brain: The effect of cell communication and Nrf2-mediated cellular defence [PDF]
Stroke and other brain injuries trigger an extensive glial cell response referred to as reactive gliosis. Reactive gliosis is characterized by hypertrophic and proliferating astrocytes, proliferating microglia and NG2-positive cells, which eventually ...
Andersson, Heléne +9 more
core +1 more source
Abstract Objective Accurate presurgical evaluation should assess not only the location but also the spatial extent of epileptic activity relative to the surgical cavity, a practical approximation of the epileptogenic zone. We evaluated how electromagnetic source imaging (EMSI) and hemodynamic responses to epileptic discharges relate to the surgical ...
Chifaou Abdallah +13 more
wiley +1 more source
Objectives: Gliosis becomes physical and mechanical barrier to axonal regeneration. Reactive gliosis induced by middle cerebral artery occlusion is involved with up-regulation of CD81 and GFAP (Glial fibrillary acidic protein).
Bong-Keun Song +5 more
doaj +1 more source

