Results 111 to 120 of about 58,440 (301)

Epileptogenic lesions in the Australian epilepsy project: A harmonized 3‐T magnetic resonance imaging protocol and its diagnostic yield

open access: yesEpilepsia, EarlyView.
Abstract Objective Detection of epilepsy‐causing structural brain lesions on magnetic resonance imaging (MRI) is critical for diagnosis, prognosis, and treatment planning in people with epilepsy. We aimed to establish an epilepsy‐directed multisite harmonized 3‐T MRI acquisition protocol for the Australian Epilepsy Project (AEP) and describe the ...
David N. Vaughan   +19 more
wiley   +1 more source

Exposure to a nanoplastic-enriched diet for fourteen days increases microglial immunoreactivity in the zebrafish telencephalon

open access: yesFrontiers in Molecular Neuroscience
Microscopic plastic particles (micro- and nanoplastics) are an emerging environmental contaminant detected in air, soil, water, and human food supplies.
Robert A. Mans   +8 more
doaj   +1 more source

Ventral anterior thalamic dysfunction distinguishes seizure generalization in temporal lobe epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Focal‐to‐bilateral tonic–clonic seizures (FBTCS) in temporal lobe epilepsy (TLE) involve thalamocortical networks, yet the functional integrity and role of specific thalamic subregions in seizure generalization remain unclear. In this cross‐sectional study, we investigated whether thalamic subregion functional connectivity patterns ...
Stacy N. Hudgins   +3 more
wiley   +1 more source

[Myelination gliosis and reactive gliosis in the developing optic nerve of the rat].

open access: yesReproduction, nutrition, developpement, 1983
Our radioautographic results obtained with light and electron microscopy confirmed that the oligodendrocytes are the only cells involved in the formation of the myelin sheath in the developing primary visual system of the rat. The oligodendrocyte, whose differentiation requires the intervention of an axonal signal, causes myelination gliosis, allowing,
J, Fulcrand, J, Valat, A, Privat
openaire   +1 more source

Does stereoelectroencephalographic depth electrode insertion alter seizure frequency? A baseline versus endpoint analysis

open access: yesEpilepsia, EarlyView.
Abstract The implantation effect refers to a transient reduction in seizure frequency following intracranial electrode insertion in patients with epilepsy, independent of therapeutic intervention. This retrospective study examined potential clinical and demographic predictors of the implantation effect in 51 patients who underwent ...
Shreyashish Roy‐Chowdhury   +8 more
wiley   +1 more source

Does age influence diagnostic outcomes in an adult cohort referred to a first‐seizure clinic?

open access: yesEpilepsia, EarlyView.
Abstract Objective The aging Danish population is associated with increasing morbidity and healthcare utilization. This study examines age‐related differences in resource utilization and diagnostic outcomes between older (65–95 years) and younger adults (18–64 years) evaluated for suspected epilepsy, including clinical management, diagnostic yield, and
Anne Line Lund Birkmose   +3 more
wiley   +1 more source

Translocator protein positron emission tomography as a biomarker for posttraumatic epilepsy and behavioral comorbidities following traumatic brain injury

open access: yesEpilepsia, EarlyView.
Abstract Objective Traumatic brain injury (TBI) induces widespread and persistent neuroinflammation, which is increasingly recognized as a key contributor to chronic sequelae including posttraumatic epilepsy (PTE), cognitive deficits, and neuropsychiatric disturbances. However, reliable biomarkers for identifying individuals at risk for these long‐term
Mohit Javalgekar   +14 more
wiley   +1 more source

Clinical significance of subclinical seizures in epilepsy presurgical evaluation: A systematic review and meta‐analysis

open access: yesEpilepsia, EarlyView.
Abstract Objective Subclinical seizures (SCSs) remain an understudied aspect of presurgical evaluation in patients with drug‐resistant epilepsy (DRE), with uncertain prevalence, distribution among epilepsy types, and predictive value for surgical outcomes.
Pilar Bosque‐Varela   +6 more
wiley   +1 more source

Automated segmentation of postsurgical resection cavities on magnetic resonance imaging in focal epilepsy: A Multicentre Epilepsy Lesion Detection study

open access: yesEpilepsia, EarlyView.
Abstract Objective Quantitative assessment of extent of tissue resection following epilepsy surgery requires accurate delineation of the resection cavity on postoperative magnetic resonance imaging (MRI). Current methods for resection cavity masking are time‐consuming and labor‐intensive, and existing automated approaches exhibit variable segmentation ...
Jieun Seo   +91 more
wiley   +1 more source

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