Results 151 to 160 of about 55,381 (288)

Graded traumatic brain injury severity differentially modulates microglial and astrocytic polarization states and response to minocycline

Neuroprotection, EarlyView.
Schematic diagram of the experimental design and key findings of traumatic brain injury (TBI) with varying severities. Mild, moderate, and severe TBI were induced in the right motor cortex of mice using the controlled cortical impact (CCI) method, with impact depths of 0.5, 1.0, and 2.0 mm, respectively. A subset of severe TBI mice received minocycline
Yan Yu, Chen Wang, Jinyu Zhu, Jiahui Du, Hao Li, Shuyi Ning, Rui Yang, Yiwen Ma, Mengyuan Yuan, Wei Shen, Huailin Wang, Huihui Jiang, Liping Chen, Haitao Wu   +13 more
wiley   +1 more source

Circadian rhythms and chronotherapy in Alzheimer's disease: Mechanisms and therapeutic implications

Neuroprotection, EarlyView.
Circadian dysregulation contributes to Alzheimer's disease through sleep disruption, clock‐gene dysfunction, neuroinflammation, impaired proteostasis, and metabolic imbalance. These alterations promote cognitive decline and disease progression, while circadian biomarkers and chronotherapeutic interventions offer opportunities for precision diagnosis ...
Bivek Singh, Filippo Pigazzani, Roberto Manfredini   +2 more
wiley   +1 more source

Fetal Brain Abnormalities Following Laser Surgery for Twin‐to‐Twin Transfusion Syndrome: Imaging Patterns and Evolution

Prenatal Diagnosis, EarlyView.
ABSTRACT Introduction Severe brain injury has been reported following fetoscopic laser ablation (FLA) for twin‐to‐twin transfusion syndrome (TTTS), but imaging patterns and temporal evolution remain poorly defined. This study aimed to characterize the progression of severe brain injury after FLA. Methods We conducted a retrospective case series of TTTS
Yada Kunpalin, Elka Miller, Ingrid Larsen, Kamini Raghuram, Catherine Windrim, Nimrah Abbasi, Greg Ryan, Tim Van Mieghem, Shiri Shinar   +8 more
wiley   +1 more source

Human Blood‐Brain Tumor Barrier on a Chip to Investigate Personalized Treatment for Glioblastoma Patients

Small, EarlyView.
A microfluidic model of the glioblastoma (GBM) margin was developed to mimic patient‐specific blood‐brain tumor barrier (BBTB) function and drug response. The platform revealed inter‐patient variability in barrier integrity and drug sensitivity, offering a tool for personalized therapy evaluation in GBM.
Minsu Ryoo, Gaeun Lee, Jinwoo Jung, Sujin Cho, Sharon Jeeho Ham, Nayeong Kang, Hyeongjin Ahn, Yu Jin Kim, JeongMin Sim, Jeongman Park, Juwon Kim, Sohyun Hwang, Jihwan Yoo, Youn‐Jung Kang, Jaejoon Lim, Jungho Ahn, Song Ih Ahn   +16 more
wiley   +1 more source

Clinicoanatomic localization of iron-rich gliosis in aphasic presentations of globular glial tauopathy. [PDF]

Brain Commun
Irwin DJ, Emrani S, Ohm DT, Trotman W, Bahena A, Teunissen-Bermeo E, Sabatini P, Das SR, Mizsei G, Prabhakaran K, Ittyerah R, Coslett HB, Massimo L, Wolk DA, Detre JA, Gee JC, Lee EB, Yushkevich P, McMillan CT, Tisdall MD.   +19 more
europepmc   +1 more source

Gliosis

, 2015
Craig Hacking, Ashesh Ranchod, Nicholas Hammond   +2 more
openaire   +1 more source

Contrast‐Induced Encephalopathy Following Elective Endovascular Aneurysm Treatment: The Role of Dual‐Energy CT and Correlation With Delphi Diagnostic Criteria

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Introduction Contrast‐induced encephalopathy (CIE) is an increasingly recognised neurological complication of iodinated contrast administration during neurointerventional procedures. Recently published 2025 Delphi‐based diagnostic criteria and management algorithms aim to standardise clinical practice; however, optimal neuroimaging strategies ...
Kaiwen Cabbabe, Charles Li, Shuangyue Tan, Lisa Broadley, Gerard S. Goh, Cameron Williams, Conor Houlihan, Helen Kavnoudias, Steve Bush, Carlos Chung, Winston Chong   +10 more
wiley   +1 more source

Taenia solium development and host interactions in neurocysticercosis: a narrative mini review on mechanistic pathways to epileptogenesis. [PDF]

Acta Epileptol
Sikakulya FK, Lekuya HM, Kamabu LK, Manzekele MK, Ochen E, Sonia FD, Baanitse JM, Pascal FNB, Shah RA, Balarabe SH, Kavulikirwa OK, Kitya D, Jones MK.   +12 more
europepmc   +1 more source

The oscillatory response of the electroretinogram and neuronal adaptation

Acta Ophthalmologica, EarlyView.
Abstract After more than 50 years, there still remains a challenge and an interest to know more as well as extend and deepen our understanding of the small rapid wavelets, the oscillatory potentials (OPs), of the electroretinogram (ERG) and the neuronal adaptation of the retina.
Lillemor Wachtmeister, Anders Eklund
wiley   +1 more source

Cell-type-specific APOE4 cascade across the Alzheimer's disease continuum. [PDF]

Neuron
Shostak D, Liang Z, Huang Y.
europepmc   +1 more source